Micro(nano)plastics in the Human Body: Sources, Occurrences, Fates, and Health Risks

Environmental Science & Technology, Год журнала: 2024, Номер unknown

Опубликована: Фев. 5, 2024

The increasing global attention on micro(nano)plastics (MNPs) is a result of their ubiquity in the water, air, soil, and biosphere, exposing humans to MNPs daily basis threatening human health. However, crucial data body, including sources, occurrences, behaviors, health risks, are limited, which greatly impedes any systematic assessment impact body. To further understand effects we must identify existing knowledge gaps that need be immediately addressed provide potential solutions these issues. Herein, examined current literature behaviors body as well risks. Furthermore, identified key resolved comprehensively assess Additionally, complexity lack efficient analytical methods main barriers impeding investigations necessitating development standard unified method. Finally, highlighted for interdisciplinary studies from environmental, biological, medical, chemical, computer, material scientists fill drive research. Considering inevitability occurrence exposure MNPs, more urgently required enhance our understanding negative

Язык: Английский

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Fate, abundance and ecological risks of microcystins in aquatic environment: The implication of microplastics

Water Research, Год журнала: 2024, Номер 251, С. 121121 - 121121

Опубликована: Янв. 8, 2024

Язык: Английский

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Photoaged Tire Wear Particles Leading to the Oxidative Damage on Earthworms (Eisenia fetida) by Disrupting the Antioxidant Defense System: The Definitive Role of Environmental Free Radicals

Environmental Science & Technology, Год журнала: 2024, Номер 58(10), С. 4500 - 4509

Опубликована: Фев. 28, 2024

Tire wear particles (TWPs) have caused increasing concerns due to their detrimental effects on the soil ecosystem. However, role of weathering in altering toxicity TWP organisms is poorly understood. In this study, original and photoaged was compared using earthworms (Eisenia fetida) as model organisms. The obtained results indicated that photoaging resulted an increase environmentally persistent free radicals (EPFRs) from 3.69 × 1017 5.20 spin/g. Meanwhile, induced changes toxic endpoint E. fetide, i.e., weight loss death ratio 0.0425 0.0756 g/worm 23.3 50% under a 10% concentration, respectively. Analyses transcriptomics, antioxidant enzyme activity, histopathology demonstrated enhanced mainly oxidative damage, which by disruption defense system. Free-radical quenching correlation analysis further suggested excessive production ex vivo reactive oxygen species, EPFRs, led exhaustion Overall, work provides new insights into potential hazard weathered environment has significant implications for recycling proper disposal spent tire particles.

Язык: Английский

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New insight into intestinal toxicity accelerated by aged microplastics with triclosan: inflammation regulation by gut microbiota-bile acid axis

Journal of Hazardous Materials, Год журнала: 2025, Номер 492, С. 138308 - 138308

Опубликована: Апрель 15, 2025

Язык: Английский

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Nanoplastics in aquatic environments: The hidden impact of aging on fate and toxicity

Environmental Chemistry and Ecotoxicology, Год журнала: 2025, Номер unknown

Опубликована: Фев. 1, 2025

Язык: Английский

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Ecological and Health Risk Mediated by Micro(nano)plastics Aging Process: Perspectives and Challenges

Environmental Science & Technology, Год журнала: 2025, Номер unknown

Опубликована: Март 19, 2025

Aged micro(nano)plastics (MNPs) are normally the ultimate state of plastics in environment after aging. The changes physical and chemical characteristics aged MNPs significantly influence their environmental behavior by releasing additives, forming byproducts, adsorbing contaminants. However, a systematic review is lacking on effects ecological human health regarding increasing but scattered studies results. This Review first summarizes unique methods for quantifying aging degree. Then we focused potential impacts organisms, ecosystems, health, including "Trojan horse" under real conditions. Through combining meta-analysis analytic hierarchy process (AHP) model, demonstrated that, compared to virgin MNPs, would result biomass decrease oxidative stress increase organisms lead total N/P greenhouse gas emissions ecosystems while causing cell apoptosis, antioxidant system reaction, inflammation health. Within framework risk assessment, used quotient (RQ) physiologically based pharmacokinetic (PBK) models as examples illustrate importance considering degree data acquisition, model building, formula evaluation. Given risks our urgent call more understand hazards real-world environments.

Язык: Английский

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Polystyrene and polyethylene perturb the structure of membrane: An experimental and computational study

Environmental Pollution, Год журнала: 2025, Номер unknown, С. 126317 - 126317

Опубликована: Апрель 1, 2025

Язык: Английский

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Photoaged polystyrene nanoplastics induce perturbation of glucose metabolism in HepG2 cells via oxidative stress

Environmental Pollution, Год журнала: 2025, Номер 379, С. 126534 - 126534

Опубликована: Май 25, 2025

Язык: Английский

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Polystyrene nanoplastics induced learning and memory impairments in mice by damaging the glymphatic system

Ecotoxicology and Environmental Safety, Год журнала: 2024, Номер 284, С. 116874 - 116874

Опубликована: Авг. 16, 2024

The excessive usage of nanoplastics (NPs) has posed a serious threat to the ecological environment and human health, which can enter brain then result in neurotoxicity. However, research on neurotoxic effects NPs based different exposure routes modifications functional groups is lacking. In this study, neurotoxicity induced by was studied using polystyrene (PS-NPs) (PS, PS-COOH, PS-NH

Язык: Английский

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The effects of nanoplastics and microcystin-LR coexposure on Aristichthys nobilis at the early developmental stages

Aquatic Toxicology, Год журнала: 2024, Номер 273, С. 107006 - 107006

Опубликована: Июнь 19, 2024

Язык: Английский

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