The Impact of Environmental Aging Processing on Bioaerosol Detection Using Circular Intensity Differential Scattering (CIDS)

Journal of Aerosol Science, Год журнала: 2025, Номер 186, С. 106555 - 106555

Опубликована: Фев. 25, 2025

Язык: Английский

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Dependence of aerosol-borne influenza A virus infectivity on relative humidity and aerosol composition

Frontiers in Microbiology, Год журнала: 2024, Номер 15

Опубликована: Окт. 16, 2024

We describe a novel biosafety aerosol chamber equipped with state-of-the-art instrumentation for bubble-bursting generation, size distribution measurement, and condensation-growth collection to minimize sampling artifacts when measuring virus infectivity in particles. Using this facility, we investigated the effect of relative humidity (RH) very clean air without trace gases (except ∼400 ppm CO 2 ) on preservation influenza A (IAV) saline characterized terms 99%-inactivation time, t 99 , metric consider most relevant airborne transmission. The viruses remained infectious long namely > 5 h, if RH < 30% particles effloresced. Under intermediate conditions (40% 70%), loss was rapid ( ≈ 15–20 min, up 35 min at 95% RH). This is more than an order magnitude faster suggested by many previous studies aerosol-borne IAV, possibly due use matrices containing organic molecules, such as proteins, protective effects virus. tested hypothesis adding sucrose our aerosolization medium and, indeed, observed protection IAV (55%). Interestingly, measurements are also systematically lower those 1-μL droplet organic-free solutions, which cannot be explained particle alone.

Язык: Английский

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Dependence of aerosol-borne influenza A virus infectivity on relative humidity and aerosol composition

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Май 28, 2024

Abstract We describe a novel biosafety aerosol chamber equipped with state-of-the-art instrumentation for bubble-bursting generation, size distribution measurement, and condensation-growth collection to minimize sampling artifacts when measuring virus infectivity in particles. Using this facility, we investigated the effect of relative humidity (RH) very clean air without trace gases (except ∼400 ppm CO 2 ) on preservation influenza A (IAV) saline characterized terms 99%-inactivation time, t 99 , metric consider most relevant airborne transmission. The viruses remained infectious long namely > 5 h, if RH < 30% particles effloresced. Under intermediate conditions (40% 70%), loss was rapid ( ≈ 15-20 min, up 35 min at 95% RH). This is more than an order magnitude faster suggested by many previous studies aerosol-borne IAV, possibly due use matrices containing organic molecules, such as proteins, protective effects virus. tested hypothesis adding sucrose our aerosolization medium and, indeed, observed protection IAV (55 %). Interestingly, measurements are also systematically lower those 1-μL droplet organic-free solutions, which cannot be explained particle alone.

Язык: Английский

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Implications of the spatiotemporal distribution of CO2 on indoor air quality: A field study with reduced-order modeling

Building and Environment, Год журнала: 2024, Номер 269, С. 112451 - 112451

Опубликована: Дек. 13, 2024

Язык: Английский

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Implications of the Spatiotemporal Distribution of Co2 on Indoor Air Quality: A Large-Scale Field Study with Reduced-Order Modeling

Опубликована: Янв. 1, 2024

Язык: Английский

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