Health risk-oriented source apportionment of PM2.5-associated trace metals

Environmental Pollution, Год журнала: 2020, Номер 262, С. 114655 - 114655

Опубликована: Апрель 23, 2020

Язык: Английский

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Exposure to ultrafine particulate matter induces NF-κβ mediated epigenetic modifications

Environmental Pollution, Год журнала: 2019, Номер 252, С. 39 - 50

Опубликована: Май 21, 2019

Язык: Английский

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Hydrophobic Organic Components of Ambient Fine Particulate Matter (PM_2.5) Associated with Inflammatory Cellular Response

Environmental Science & Technology, Год журнала: 2019, Номер 53(17), С. 10479 - 10486

Опубликована: Авг. 9, 2019

Nowadays, knowledge regarding component-specific inflammatory effect of fine particulate matter (PM2.5) is limited. In this study, an omics approach based on time-of-flight mass spectrometry was established to identify the key hydrophobic components PM2.5 associated with pro-inflammatory cytokines released by macrophages after in vitro exposure. Of 764 compounds, 62 were robustly screened firmly identified 37 specific chemicals. addition polycyclic aromatic hydrocarbons (PAHs) and their methylated congeners, novel oxygen- nitrogen-containing PAHs and, especially, oxygenated (Oxy-PAHs) identified. Interleukin (IL)-6 Oxy-PAHs 1,8-naphthalic anhydride, xanthone, benzo[h]quinolone, whereas IL-1β tumor necrosis factor (TNF)-α most species. Most species related IL-1β, which significantly higher heating season, a monotonic dose–response pattern mainly for U-shaped primary On basis components, four sources pollution (coal combustion, traffic emissions, biomass burning, secondary formation, traced such as anhydride quinones) resolved positive matrix factorization model. TNF-α sources, IL-6 both suggesting different effects between when assessing toxicity-driven disparities known unknown components.

Язык: Английский

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Tris(2,4-di-tert-butylphenyl)phosphate: An Unexpected Abundant Toxic Pollutant Found in PM_2.5

Environmental Science & Technology, Год журнала: 2020, Номер 54(17), С. 10570 - 10576

Опубликована: Авг. 10, 2020

A novel pollutant, tris(2,4-di-tert-butylphenyl)phosphate (I168O), was identified in urban fine particulate matter (PM2.5) samples a nontargeted screening based on mass spectrometry for the first time. I168O detected all collected from two typical cities far away each other China. The concentrations of reached up to 851 (median: 153) ng/m3, indicating that it widespread and abundant pollutant air. antioxidant Irgafos 168 [I168, tris(2,4-di-tert-butylphenyl)phosphite] popularly added plastics most suspected source I168O. Simulation studies indicated heating, UV radiation, water contact might significantly (p < 0.05) transform I168 In particular, be magnificently evaporated into air at high temperatures. outdoor inhalation exposure may exert substantial health risks.

Язык: Английский

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Biological Aerosol Particles in Polluted Regions

Current Pollution Reports, Год журнала: 2020, Номер 6(2), С. 65 - 89

Опубликована: Фев. 22, 2020

Язык: Английский

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