Springer eBooks, Год журнала: 2023, Номер unknown, С. 317 - 339
Опубликована: Янв. 1, 2023
Язык: Английский
Gut Microbes, Год журнала: 2024, Номер 16(1)
Опубликована: Ноя. 21, 2024
Human milk oligosaccharides (HMOs) are the third most important nutrient in human and gold standard for infant nutrition. Due to lack of an enzyme system capable utilizing HMOs intestine, cannot be directly utilized. Instead, they function as natural prebiotics, participating establishment intestinal microbiota a "bifidus factor." A crucial colonizer early intestine is
Язык: Английский
Процитировано
2
Опубликована: Июнь 3, 2024
The gut has been a focus of chronic disease research. microbiota produces metabolites that act as signaling molecules and substrates, closely influencing host health. Indigestible oli-gosaccharides (NDOs), common dietary fiber, play an important role in regulating the structure function microbiota. Their mechanism action is mainly attributed to their carbon source specific probiotics, producing related metabolites, mi-crobial community. However, due selective utilization oligosaccharides, some factors such types structures oligosaccharides have different impacts on composition microbial populations production colon ecosystem. This review systematically describes key microorganisms elaborates how affect host's immune system, inflam-mation levels energy metabolism by diversity metabolic function, which turn will onset progress diseases, especially diabetes, obesity, depression intestinal inflammatory constipation. In this review, we re-examine interaction mechanisms between its associated explore new strategies for promoting human health combating diseases through di-etary interventions.
Язык: Английский
Процитировано
1
Food Research International, Год журнала: 2024, Номер 197, С. 115236 - 115236
Опубликована: Окт. 21, 2024
Язык: Английский
Процитировано
1
Microorganisms, Год журнала: 2024, Номер 12(8), С. 1582 - 1582
Опубликована: Авг. 2, 2024
Probiotics are “live microorganisms which, when administered in adequate amount, confer health benefits on the host”. They can be found certain foods like yogurt and kefir dietary supplements. The introduction of bacterial derivatives has not only contributed to disease control but also exhibited promising outcomes, such as improved survival rates, immune enhancement, growth promotion effects. It is interesting note that efficacy probiotics goes beyond viability bacteria, giving rise concepts paraprobiotics, non-viable forms probiotics, postbiotics. Paraprobiotics offer various children with intestinal dysbiosis, contributing digestive health, function, overall well-being. In this review, potential these therapeutic applications alternatives pharmacological agents for treating pediatric dysbiosis will thoroughly evaluated. This includes an analysis their efficacy, safety, long-term benefits, ability restore gut microbiota balance, improve enhance reduce inflammation. aim determine if non-pharmacological interventions effectively safely manage children, reducing need conventional medications side
Язык: Английский
Процитировано
1
Опубликована: Янв. 8, 2024
Breastmilk provides valuable nutrients and immune protection for preventing several childhood mortality chronic disorders throughout the life course. Human Milk Oligosaccharides (HMOs), as a bioactive constituent in breastmilk, foster healthy microbiota infants due to their prebiotic effects. The complex interplay between HMOs beneficial bacteria, both directly indirectly, promotes growth of infants' gastrointestinal systems. Additionally, provide stereospecific against various pathogens by avoiding pathogenic adherence epithelial cells. This is effective viruses, parasites. review fills gap knowledge investigating relationship HMOs, infant microbiota, function. contributes development formula feeding HMOs-related drugs. Future studies could further investigate diverse gut microbial system specific mechanisms functional groups immunomodulation. More human-based randomized controlled trials are needed.
Язык: Английский
Процитировано
0
Food Science of Animal Products, Год журнала: 2024, Номер 2(1), С. 9240052 - 9240052
Опубликована: Март 1, 2024
Breast milk is the preferred gold standard food for infants. Human oligosaccharides (HMOs) are third most natural component in breast milk. But often insufficient, so they rely solely on substitutes. HMOs provide nutrients to beneficial gut microbiota such as Lactobacilli and Bifidobacteria, helping establish maintain a balance of microbial communities infant gut. mimic receptors pathogens, preventing them from attaching baby's intestinal cells, thereby pathogen infection. This function particularly crucial newborns How individually use important. We focused classification characteristics HMOs, their impact, intake, development/utilization mechanism health, aiming data support development. quite different (more than 200 kinds), it necessary make targeted selection, those associated with microorganisms (Bifidobacterium), which can utilize have greatest application potential. Oligosaccharide-binding protein (OBPs) an important medium ATP-binding cassette transporter channel transport; influence key OBPs Bifidobacterium recognition infants various countries has been explored, helpful accelerate establishment precise personalized powder future. The more significance results this review help consumers better choose promoting long-term health infants, especially early development immune system.
Язык: Английский
Процитировано
0
Springer eBooks, Год журнала: 2023, Номер unknown, С. 317 - 339
Опубликована: Янв. 1, 2023
Язык: Английский
Процитировано
0