Acute
pesticide
poisoning
has
resulted
in
several
symptoms
that
threaten
life
safety.
Thus,
developing
a
rapid
detection
method
would
facilitate
the
identification
of
toxicants
as
soon
possible.
This
study
presented
an
affordable
and
straightforward
platform
based
on
core-shell
structure
nanocomposite
Prussian
blue/Fe-metal-organic
frameworks/Ce
material,
which
exhibited
peroxidase-like
activity
multiple
capture
sites
[marked
phosphate
buffer
(PB)/Fe-MOF/Ce
NPs].
Fe3+
Fe2+
are
located
at
core
PB
nanoparticles
(PB
NPs),
metal-porphyrin
metal-organic
framework
(MOF)
shell,
Ce
NPs
grown
shell.
A
practical,
economical,
accurate,
colorimetric
strategy
was
synthesized
to
detect
organophosphorus
pesticides
directly
fetal
bovine
serum.
The
solution-based
PB/Fe-MOF/Ce
NP
sensor
demonstrated
ultrasensitive
performance
excellent
reproducibility.
absorbance
variation
dichlorvos,
methamidophos,
dimethoate
follows
linear
equation
y
=
0.093x
+
0.024,
0.083x
0.017,
0.114x
0.117
under
low
content,
limit
(LOD)
determined
using
3s/slope,
5.6,
4.8,
6.5
μg/L,
respectively,
with
recovery
rates
ranging
from
83.4%
98.6%
RSD
less
than
6%.
provides
for
effectively
detecting
acute
samples
offers
profound
insights
further
improving
treatment
efficiency
poisoning,
it
prospects
clinical
point-of-care
testing.
Journal of Agricultural and Food Chemistry,
Год журнала:
2024,
Номер
72(8), С. 4405 - 4414
Опубликована: Фев. 15, 2024
The
photothermal
lateral
flow
immunoassay
(LFIA)
is
of
great
significance
to
suitable
for
on-site
semiquantitative
detection,
which
has
the
upper
hand
in
further
constructing
detection
methods
low-concentration
targets.
Herein,
we
presented
a
doping
engineering-powered
nanoheterostructure
with
an
enhanced
performance
strategy,
employing
bimetallic
nanocuboid
Pt3Sn
(PSNCs)
as
proof
concept.
With
help
finite
element
simulation
analysis,
contrast
direct
temperature
experiment,
and
evaluation
conversion
efficiency
(η),
distinguished
enthusiastic
feedback
PSNCs
proved.
Based
on
steady
bright
black
colorimetric
superior
performance,
were
employed
construct
ultrasensitive
model
LIFA
detecting
Salmonella
typhimurium
(S.
typhimurium),
achieved
double-signal
limit
reached
103
cfu
mL–1
(colorimetric
mode)
102
(photothermal
mode),
100
times
higher
than
that
traditional
colloidal
gold
method.
In
addition,
method
was
effective
targets
dairy
samples
only
through
simple
dilution
treatment,
completed
within
15
min.
Meanwhile,
this
dual-signal
LFIA
demonstrated
sensitive
S.
due
excellent
signal
significant
provides
broad
spectrum
future
foodborne
pathogens.
ACS Applied Bio Materials,
Год журнала:
2024,
Номер
7(5), С. 3346 - 3357
Опубликована: Май 2, 2024
Septicemia,
a
severe
bacterial
infection,
poses
significant
risks
to
human
health.
Early
detection
of
septicemia
by
tracking
specific
biomarkers
is
crucial
for
timely
intervention.
Herein,
we
developed
molecularly
imprinted
(MI)
TiO2–Fe–CeO2
nanozyme
array
derived
from
Ce[Fe(CN)6]
Prussian
blue
analogues
(PBA),
specifically
targeting
valine,
leucine,
and
isoleucine,
as
potential
indicators
septicemia.
The
synthesized
arrays
were
thoroughly
characterized
using
various
analytical
techniques,
including
Fourier
transform
infrared
spectroscopy,
X-ray
diffraction,
field-emission
scanning
electron
microscope,
energy-dispersive
X-ray.
results
confirmed
their
desirable
physical
chemical
properties,
indicating
suitability
the
oxidation
3,3′,5,5′-tetramethylbenzidine
serving
colorimetric
probe
in
presence
persulfate
oxidizing
agent,
further
highlighting
these
sensitive
accurate
applications.
MITiO2
shell
selectively
captures
partially
blocking
cavities
substrate
access
thereby
hindering
catalyzed
TMB
chromogenic
reaction.
demonstrated
excellent
performance
with
linear
ranges
5
μM
1
mM,
10–450
μM,
respectively.
Notably,
corresponding
limit
values
0.69,
1.46,
2.76
assay
exhibited
outstanding
selectivity,
reproducibility,
analytes
blood
samples,
C-reactive
protein
at
concentration
61
mg/L,
procalcitonin
870
ng/dL,
Pseudomonas
aeruginosa
bacteria.
utilization
Ce[Fe(CN)6]-derived
MITiO2–Fe–CeO2
holds
considerable
field
detection.
This
approach
offers
method
early
diagnosis
intervention,
contributing
improved
patient
outcomes.
Analytical Chemistry,
Год журнала:
2024,
Номер
96(36), С. 14706 - 14713
Опубликована: Авг. 29, 2024
Concerns
regarding
the
hazard
of
carcinogenic
ethyl
carbamate
(EC)
have
driven
attempts
to
exploit
efficient,
timely,
straightforward,
and
economic
assays
for
warning
early
food
safety.
Here,
we
proposed
a
novel
molecularly
imprinted
polymer
Co@MOF-MIP,
with
high
peroxidase
(POD)-like
activity
bright
blue
fluorescence
emission,
develop
versatile
visual
assay
colorimetric,
fluorescent,
photothermal
trimodal
detection
logic
gate
outputting
EC.
Briefly,
POD-like
Co@MOF-MIP
made
it
decompose
H2O2
into
·OH
oxidizing
colorless
3,3′,5,5′-tetramethylbenzidine
(TMB)
oxTMB,
resulting
in
660
nm
irradiated
effect
bursting
via
inner
filter
effect,
observing
decreased
signal
together
an
increased
colorimetric
signals.
However,
EC
could
specifically
fill
cavities
block
catalytic
substrates
TMB
out
further
reacting
inside
center
Co2+,
transformation
suppressing
yielding
concentration-dependent
responses
enhancement,
decreases.
Assisted
by
portable
devices
such
as
smartphones
hand-held
thermal
imagers,
onsite
analytical
platform
was
fast
accurate
low
limits
1.64,
1.24,
1.78
μg/L
modes,
respectively.
Interestingly,
these
reactive
events
be
programmed
classical
Boolean
analysis
offer
promising
avenue
big
data
Internet
Things
monitoring
residual
more
intelligent,
dynamical,
fast,
manner,
safeguarding
