SSRN Electronic Journal,
Год журнала:
2022,
Номер
unknown
Опубликована: Янв. 1, 2022
The
coupling
reaction
allows
simple
structural
fragments
to
be
constructed
and
sequentially
assembled
by
C-X
bond
synthesize
a
variety
of
active
molecular
frameworks.
Different
from
the
traditional
single-metal
catalyst,
synergistic
effect
bimetal
provides
special
catalytic
activity
that
cannot
obtained
thus
emerging
as
an
efficient
alternative
mode.
In
this
paper,
we
used
Cu-Al
bimetallic
heterogeneous
mesoporous
materials
participate
in
sequential
assembly
C-S
C-N
bonds,
which
effectively
catalyzed
synthesis
2-substituted
benzothiazole
heterocyclic
systems.
addition,
GW610
with
antitumor
was
synthesized
easily
efficiently
strategy.
Organic Chemistry Frontiers,
Год журнала:
2023,
Номер
10(13), С. 3252 - 3258
Опубликована: Янв. 1, 2023
A
novel
one-pot
method
for
synthesizing
polysubstituted
pyrrole
derivatives
via
three-component
reactions
of
alkenyl
bromides,
amines,
and
isocyanides
is
reported
by
Pd
catalysis,
without
additional
ligands,
with
the
orderly
insertion
three
isocyanide
molecules.
Organic Letters,
Год журнала:
2022,
Номер
24(3), С. 859 - 863
Опубликована: Янв. 12, 2022
Herein
a
novel
and
concise
approach
to
pyrrole
skeletons
via
Pd-catalyzed
tandem
cyclization
reactions
is
investigated.
The
substrates
for
the
transformation
could
be
readily
prepared
by
phosphoric
acid-catalyzed
Ugi
with
available
starting
materials.
In
this
strategy,
two
isocyanides
participate
in
sequential
isocyanide
insertion
reactions,
chemoselectivity
of
products
regulated
steric
hindrance
isocyanide.
A
plausible
mechanism
formation
corresponding
adducts
proposed.
Organic Chemistry Frontiers,
Год журнала:
2021,
Номер
8(19), С. 5296 - 5302
Опубликована: Янв. 1, 2021
A
visible-light-driven
photocyclization
reaction
of
aryl
azides
to
access
2
H
-indazole-3-carboxamides
in
moderate
excellent
yields
has
been
realized
efficiently
under
photocatalyst-free
and
external
additive-free
conditions.
New Journal of Chemistry,
Год журнала:
2021,
Номер
45(21), С. 9614 - 9620
Опубликована: Янв. 1, 2021
An
amazing
and
stable
carbonized
octahedral
frame
material
Cu-PC@OFM
was
synthesized
characterized
through
HRTEM,
SEM,
XRD,
XPS,
Raman
spectroscopy
nitrogen
adsorption/desorption
analysis.
Organic Chemistry Frontiers,
Год журнала:
2024,
Номер
11(6), С. 1775 - 1781
Опубликована: Янв. 1, 2024
We
have
successfully
demonstrated
an
efficient
and
practical
Pd-catalyzed
reaction
between
aziridine
isocyanide,
leading
to
the
synthesis
of
isoindoline
derivatives
in
moderate
good
yields.
Abstract
Herein,
a
straightforward
method
for
the
construction
of
tetrazole
derivatives
has
been
achieved
through
Pd‐catalyzed
isocyanide
insertion
reactions,
which
is
good
extension
response
multi‐molecule
isocyanides.
The
Ugi‐N
3
reaction
was
introduced
to
transformation
enrich
diversity
skeleton
structures.
commercially
available
starting
materials
and
moderate
yields
make
this
valuable
tool
generating
N‐containing
heterocyclic
compounds.
ChemistrySelect,
Год журнала:
2021,
Номер
6(45), С. 12921 - 12925
Опубликована: Дек. 2, 2021
Abstract
In
this
work,
an
efficient
synthesis
of
indole
derivatives
through
palladium‐catalyzed
double
isocyanide
insertion
reactions
has
been
developed.
The
reaction
intermediates
could
be
readily
obtained
by
Ugi
reactions.
transformation
features
broad
functional‐group
compatibility,
commercially
available
starting
materials,
and
moderate
to
good
yields.
Furthermore,
the
bioactivities
synthesized
compounds
were
evaluated
in
mycelial
growth
tests
against
Penicilium
digitatum
Colletotrichun
gloeosporioides,
showed
potential
antifungal
activities.
Synthesis,
Год журнала:
2021,
Номер
53(17), С. 3011 - 3018
Опубликована: Янв. 27, 2021
Abstract
Regioselective
coupling
reaction
of
N-substituted
imidazoles
with
isocyanates
in
the
presence
a
stoichiometric
amount
hydrosilanes
catalyzed
by
Ir4(CO)12
to
give
imidazole-2-carboxamides
is
reported.
Imidazoles
bearing
an
(O-silyl)carboximidate
group
at
2-position
appear
be
initially
formed
reaction;
these
are
then
hydrolyzed
final
products
situ.
The
addition
hydrosilane
was
essential
for
catalytic
proceed.
Substituents
on
imidazole
ring
had
no
effect
reaction,
except
certain
bulky
substituents
such
as
t
Bu
and
Ph
groups
4-position.
Triazoles
4-methyl-4H-1,2,4-triazole
1-methyl-1H-1,2,4-triazole
were
also
applicable
this
C–H
amidation,
latter
proceeded
regioselectively
carbon
atom
between
sp3
sp2
nitrogen
atoms
ring,
not
two
atoms.
