Physical Chemistry Chemical Physics, Год журнала: 2024, Номер unknown
Опубликована: Янв. 1, 2024
The mechanism, regioselectivity, and chemoselectivity in a gold-catalyzed oxidative cyclization of diynones with alcohols to give furan-3-carboxylate derivatives were explored by density functional theory (DFT). obtained results revealed that the first step global reaction involves nucleophilic attack pyridine-
Язык: Английский
RSC Advances, Год журнала: 2024, Номер 14(29), С. 21047 - 21064
Опубликована: Янв. 1, 2024
Synthesis of quinoid heteroaryls via gold-catalyzed cascade protocols: recent advances and methodologies.
Язык: Английский
Процитировано
7
Asian Journal of Organic Chemistry, Год журнала: 2021, Номер 10(12), С. 3127 - 3165
Опубликована: Окт. 11, 2021
Abstract Isoxazoles are an important class of heterocycles with nitrogen and oxygen in a 1,2‐relationship. They find wide applications synthetic organic chemistry part several drug molecules. Since the last two decades, great progress has been achieved synthesis functionalization isoxazoles, which transition metal catalysis played pivotal role towards achieving this goal. In particular, (TM)‐mediated site‐selective functionalizations isoxazoles retain pharmacologically synthetically valuable isoxazole skeleton, highly appealing. This comprehensive review is solely dedicated to TM‐mediated wherein we have included as directing groups (DG) for TM‐catalyzed C−H reactions, direct functionalization, along cross‐coupling reactions annulation finally ring‐opening under TM‐catalysis also discussed. Also, incorporated discussions on reaction designs, their advantages limitations, mechanistic details challenges that need be addressed inspire medicinal chemists explore new arenas make use key scaffold.
Язык: Английский
Процитировано
30
Organic Letters, Год журнала: 2025, Номер unknown
Опубликована: Март 28, 2025
3-Allylindoles constitute a key structural feature in many natural products and bioactive compounds. In this work, we developed Mo-mediated reductive cyclization/allylation of 2-alkynyl nitroarenes with 1,3-dienes. Using Mo(CO)6 as both the reductant catalyst, broad range functionalized 3-allylindoles were prepared good to excellent yields from easily available 2-alkynylnitroarenes 1,3-dienes starting materials.
Язык: Английский
Процитировано
0
Organic & Biomolecular Chemistry, Год журнала: 2023, Номер 21(10), С. 2127 - 2137
Опубликована: Янв. 1, 2023
A new catalytic method for the construction of quinobenzoxazine core has been developed employing gold-catalyzed cyclization o-azidoacetylenic ketones in presence anthranils. The overall process comprises a 6-endo-dig cyclisation ketone leading to α-imino gold carbene and subsequent transfer anthranil 3-aryl-imino-quinoline-4-one intermediate, which undergoes 6π-electrocyclization aromatization form central core. This transformation provides approach diverse array structures, addition being scalable having mild reaction conditions.
Язык: Английский
Процитировано
4
Advanced Synthesis & Catalysis, Год журнала: 2022, Номер 364(6), С. 1122 - 1133
Опубликована: Фев. 1, 2022
Abstract The possibility of interrupting the gold‐catalysed intramolecular cyclization 2‐alkynylphenylazide derivatives, employing known nitrene transfer reagents such as anthranil and its isomer 1,2‐benzisoxazole, has been attempted in search developing simple tools for product diversification. With 1,2‐benzisoxazoles, intermolecular leading to quinazoline is competitive with azidoalkyne resulting spiro indol‐3‐ylidene derivatives. However, case reaction presence anthranil, both intra‐ processes result same indol‐3‐ylidene. magnified image
Язык: Английский
Процитировано
6
Progress in heterocyclic chemistry, Год журнала: 2023, Номер unknown, С. 425 - 468
Опубликована: Янв. 1, 2023
Язык: Английский
Процитировано
3
Organic & Biomolecular Chemistry, Год журнала: 2022, Номер 20(48), С. 9742 - 9745
Опубликована: Янв. 1, 2022
The direct conversion of aryl boronic acids and anthranils to acridines has been realized herein, via the catalysis copper species under acidic conditions.
Язык: Английский
Процитировано
4
DELETED, Год журнала: 2022, Номер 88(4), С. 501 - 527
Опубликована: Сен. 5, 2022
Gold catalysis has emerged as an important tool in the field of synthetic organic chemistry for selective functionalization C–C multiple bonds. The research India on gold focuses diverse fields starting from methodology developments to synthesis molecular scaffolds their potential application medicinal and material science. Herein, we present a comprehensive overview gold-catalyzed transformations that were reported last fifteen years.
Язык: Английский
Процитировано
3
Acta Crystallographica Section E Crystallographic Communications, Год журнала: 2024, Номер 80(3), С. 310 - 313
Опубликована: Фев. 20, 2024
An attempt to explore the reactivity of nitro group in presence gold catalysis comparison azide yielded intriguing results. Surprisingly, only exhibited reactivity, ultimately giving rise formation title isatogen, C 14 H 8 N 4 O 2 . In crystal structure, weak C—H...O hydrogen bonds and π–π stacking interactions link molecules. The structure exhibits disorder molecule.
Язык: Английский
Процитировано
0
Physical Chemistry Chemical Physics, Год журнала: 2024, Номер unknown
Опубликована: Янв. 1, 2024
The mechanism, regioselectivity, and chemoselectivity in a gold-catalyzed oxidative cyclization of diynones with alcohols to give furan-3-carboxylate derivatives were explored by density functional theory (DFT). obtained results revealed that the first step global reaction involves nucleophilic attack pyridine-
Язык: Английский
Процитировано
0