Angewandte Chemie,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 21, 2025
Abstract
Oximes
are
important
intermediates
for
various
chemicals
synthesis
such
as
pharmaceuticals,
among
which
one
vital
precursor
producing
neurological
disease,
antimicrobial
and
anticancer
agents
is
piperidone
oxime
(PDO).
Compared
with
conventional
thermocatalytic
method,
it's
more
attractive
to
synthesize
PDO
via
green
electrocatalytic
technology
especially
utilizing
waste
nitrogen
oxides
gas
source.
However,
there
great
challenges
in
catalyst
design
high‐efficiency
electrosynthetic
due
the
low
electron
transport
rate
multiple
competing
reactions.
Herein,
we
propose
an
interfacial
coordination
strategy
based
on
metal–organic
frameworks
(MOF)
electrocatalyst
first
time
promote
electrosynthesis,
by
building
Zn−O
bridges
between
graphite
felt
(GF)
zeolitic
imidazolate
framework
(ZIF‐7/CGF).
Specially,
ZIF‐7/CGF
delivers
a
Faraday
efficiency
(FE)
of
75.9
%
yield
up
73.1
1‐methyl‐4‐piperidone
oxime,
far
superior
without
(a
FE
10.7
10.3
%).
In‐depth
mechanism
study
shows
that
introducing
can
transfer
induce
Zn
sites
transforming
into
distorted
tetrahedron
(Zn‐N
3
O)
mode,
benefits
adsorption
conversion.
The
developed
presents
wide
universalities
towards
oximes
electrosynthesis
adapts
other
MOF
materials
(ZIF‐8,
ZIF‐4).
This
work
provides
new
insights
organic
upgrading
cycle
through
rational
surficial
coordinated
electrocatalysts.
Chemical Society Reviews,
Год журнала:
2023,
Номер
52(23), С. 8106 - 8125
Опубликована: Янв. 1, 2023
This
tutorial
review
delves
into
the
unique
advantages
of
electrochemistry
in
context
asymmetric
catalysis,
first
providing
a
brief
introduction
to
electrosynthesis,
then
exploring
representative
case
studies
with
mechanistic
focus.
Nature Communications,
Год журнала:
2025,
Номер
16(1)
Опубликована: Янв. 2, 2025
Electrochemical
alcohol
oxidation
(EAO)
represents
an
effective
method
for
the
production
of
high-value
carbonyl
products.
However,
its
industrial
viability
is
hindered
by
suboptimal
efficiency
stemming
from
low
reaction
rates.
Here,
we
present
a
synergistic
electrocatalysis
approach
that
integrates
active
electrode
and
aminoxyl
radical
to
enhance
performance
EAO.
The
optimal
(4-acetamido-2,2,6,6-tetramethylpiperidine
1-oxyl)
Ni0.67V0.33-layered
double
hydroxide
(LDH)
are
screen
as
cooperative
electrocatalysts
integrating
theoretical
predictions
experiments.
Ni0.67V0.33-LDH
facilitates
adsorption
activation
N-(1-hydroxy-2,2,6,6-tetramethylpiperidin-4-yl)acetamide
(ACTH)
via
interactions
with
ketonic
oxygen,
thereby
improving
selectivity
yield
at
high
current
densities.
electrolysis
process
scaled
up
produce
200
g
steroid
product
8b
(19-Aldoandrostenedione),
achieving
91%
productivity
243
h-1.
These
results
represent
promising
accelerating
electron
transfer
oxidation,
highlighting
potential
practical
electrosynthesis
applications.
electrooxidation
due
authors
report
(Ni0.67V0.33-layered
hydroxide)
alcohols
Chemical Communications,
Год журнала:
2021,
Номер
58(5), С. 619 - 628
Опубликована: Дек. 17, 2021
This
article
summarizes
recent
examples
of
synthesis
active
ingredients
involving
electrochemical
steps
and
discusses
the
merits
electroorganic
in
terms
green
chemistry.
Advanced Synthesis & Catalysis,
Год журнала:
2022,
Номер
364(7), С. 1319 - 1325
Опубликована: Фев. 23, 2022
Abstract
An
atom
and
step
economy
cascade
trifluoromethylation/cyclization
of
unactivated
alkene
with
Langlois
reagent
as
a
CF
3
source
is
described.
A
variety
polycyclic
quinazolinones
were
successfully
synthesized
in
52–81%
yields
under
transition
metal‐
oxidant‐free
conditions.
The
used
this
strategy
possesses
the
advantages
bench‐stablity,
cost‐effectivity
high‐efficiency.
Additionally,
gram‐scale
reaction,
broad
substrate
scope
good
functional
group
tolerance
demonstrated
synthetic
usefulness
protocol.
magnified
image
Organic Letters,
Год журнала:
2022,
Номер
24(24), С. 4354 - 4359
Опубликована: Июнь 14, 2022
Electrosynthesis
is
effectively
employed
in
a
general
regio-
and
stereoselective
alkylation
of
Morita–Baylis–Hillman
compounds.
The
exposition
N-acyloxyphthalimides
(redox-active
esters)
to
galvanostatic
electroreductive
conditions,
following
the
sacrificial-anode
strategy,
proved
an
efficient
practical
method
access
densely
functionalized
cinnamate
oxindole
derivatives.
High
yields
(up
80%)
wide
functional
group
tolerance
characterized
methodology.
A
tentative
mechanistic
sketch
proposed
based
on
dedicated
control
experiments.
ACS Organic & Inorganic Au,
Год журнала:
2023,
Номер
4(2), С. 141 - 187
Опубликована: Ноя. 29, 2023
Electrosynthesis
is
a
popular,
environmentally
friendly
substitute
for
conventional
organic
methods.
It
involves
using
charge
transfer
to
stimulate
chemical
reactions
through
the
application
of
potential
or
current
between
two
electrodes.
In
addition
electrode
materials
and
type
reactor
employed,
strategies
controlling
have
an
impact
on
yields,
product
distribution,
reaction
mechanism.
this
Review,
recent
advances
related
electroanalysis
applied
in
electrosynthesis
were
discussed.
The
first
part
study
acts
as
guide
that
emphasizes
foundations
electrosynthesis.
These
essentials
include
instrumentation,
selection,
cell
design,
methodologies.
Then,
electroanalytical
techniques
organic,
enzymatic,
microbial
are
illustrated
with
specific
cases
studied
literature.
To
conclude,
discussion
future
possibilities
intend
advance
academic
industrial
areas
presented.
