Cited by Five-membered ring systems: pyrroles and benzo analogs

Modular Synthesis of Tetrasubstituted Pyrroles through a Four-Component Cyclization Strategy Using Ammonium Salt as the Nitrogen Source DOI

Chunlan Zhou,

Haolin Zheng,

Ya Chen

и другие.

The Journal of Organic Chemistry, Год журнала: 2023, Номер 88(3), С. 1533 - 1544

Опубликована: Янв. 19, 2023

A four-component synthesis of tetrasubstituted pyrroles was developed under metal-free conditions. The pyrrole ring formed in one pot through [2 + 1 1] condensation using ammonium salt as the nitrogen source. In this strategy, 1,4-naphthoquinones and maleimides were used versatile C2 fragments to provide substituted benzo[f]isoindole-4,9-diones pyrrolo[3,4-c]pyrrole-1,3-diones, respectively. This work is highlighted by source, readily available starting materials multibond formation (two C–C two C–N bonds) a single operation.

Язык: Английский

Процитировано

New Avenues for the Synthesis of Oxa‐Cycles Using Lewis/Brønsted Acid mediated Carboxygenation and Carboalkoxylation of Alkynes DOI

Santosh K. Nanda, Laxmi Narayan Nanda, Juhi Pal

и другие.

European Journal of Organic Chemistry, Год журнала: 2024, Номер 27(19)

Опубликована: Апрель 16, 2024

Abstract The cascade functionalizations of alkynes have provided many elegant methods for the synthesis useful scaffolds. Amongst these functionalizations, ones comprising C−C and C−O bond formation been utilized extensively due to abundant presence oxygenated motifs in various bio‐active natural as well unnatural products. Transition‐metal catalysis is a mainstay tandem they are very efficient. However, their utilization does typically involve stoichiometric additives like other metal salts and/or Lewis acids/Brønsted acids (LA/BA). Thus, approaches that rely solely on using LA/BA, make vital transformations not only eco‐friendly atom economical but also cost beneficial fast emerging complementary alternatives. present review addresses gap literature by summarizing recent developments LA/BA mediated 1,1/1,2‐carboxygenation carboalkoxylation oxa‐cycles. reaction mechanisms particularly emphasized bring out understanding needed from point future this domain.

Язык: Английский

Процитировано

Cascade radical cyclization on 3-propargyl-2-alkenyl indole gives stereoselective access to cyclohepta[b]indole over carbazole DOI

Santosh J. Gharpure, Sanyog Kumari

Chemical Communications, Год журнала: 2023, Номер 60(5), С. 538 - 541

Опубликована: Ноя. 27, 2023

Cascade radical cyclization on 3-propargyl-2-alkenyl indole gives stereoselective access to cyclohepta[ b ]indole over carbazole.

Язык: Английский

Процитировано

Synthesis of Multi-Substituted Pyrroles by Lewis Acid Promoted Cyclization Of N-Sulfonyl Vinylogous Carbamates and Amides DOI

Matthew G. Donahue, Gavin J. Rustin

Опубликована: Янв. 1, 2023