Organic Letters,
Год журнала:
2024,
Номер
26(15), С. 3289 - 3293
Опубликована: Апрель 3, 2024
Pseudoindoxyl
is
a
partial
skeleton
found
in
various
natural
products.
Its
light-absorption
properties
make
it
useful
for
the
design
of
functional
molecules.
However,
versatile
synthesis
methods
have
not
yet
been
reported.
In
this
report,
we
present
synthetic
method
pseudoindoxyls
using
direct
S0
→
Tn
transition
under
visible
light
irradiation.
We
also
discuss
application
as
photocatalysts.
Organic Letters,
Год журнала:
2023,
Номер
25(45), С. 8162 - 8167
Опубликована: Ноя. 6, 2023
We
have
developed
an
efficient
and
green
strategy
for
the
synthesis
of
C2-amino
indolin-3-ones
C2-acyloxy
via
KI-catalyzed
C(sp3)–H
amination
acyloxylation
using
air
as
oxidant.
The
reaction
provides
straightforward
access
to
2-substituted
by
direct
functionalization
at
C2
position
under
mild
conditions.
Moreover,
conditions
enable
a
range
complex
pharmaceuticals,
providing
attractive
products
medicinal
chemistry
programs.
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(7), С. 4673 - 4683
Опубликована: Март 13, 2024
The
cascade
electrochemical
C3-selective
aerobic
oxygenation
of
2-substituted
indoles
and
[5
+
3]
annulation
with
amidines
through
an
undivided
cell
galvanostatic
method
employing
molecular
oxygen
"electricity"
as
green
oxidants
was
developed.
This
protocol
provides
efficient
direct
approach
to
eight-membered
benzo[1,3,5]triazocin-6(5H)-ones.
Mechanistic
studies
suggested
that
two
subsequent
processes
both
proceeded
radical
pathways.
Organic Chemistry Frontiers,
Год журнала:
2024,
Номер
11(11), С. 3186 - 3195
Опубликована: Янв. 1, 2024
Three
typical
substrates
for
the
Mannich
reaction,
p
-anisidine,
aldehyde,
and
a
nucleophile,
did
not
afford
predictable
linear
base
under
an
aerobic
copper
oxidation
condition,
but
rendering
2,2-disubstituted
indolin-3-one
product.
Organic & Biomolecular Chemistry,
Год журнала:
2024,
Номер
22(35), С. 7074 - 7091
Опубликована: Янв. 1, 2024
The
present
review
highlights
the
dearomatization
of
indoles
by
oxidizing
C–H
bonds
for
constructing
oxindoles
skeletons.
Various
synthetic
approaches
have
been
summarized
followed
their
applications
in
indole
alkaloids
and
bioactive
compounds.
The Journal of Organic Chemistry,
Год журнала:
2023,
Номер
88(15), С. 11111 - 11121
Опубликована: Июль 25, 2023
A
straightforward
method
has
been
developed
to
synthesize
2-aryl-3-(2-aminoaryl)
quinoxalines
from
2-arylindoles
and
1,2-diaminoarenes
under
mild
electrochemical
conditions.
The
reaction
proceeds
through
in
situ
generations
of
2-arylindole-3-ones
oxidative
dearomatization
2-arylindoles,
followed
by
a
ring
opening-cyclization
sequence
with
1,2-diaminoarenes.
series
have
prepared
moderate
good
yields
(up
75%).
Organic & Biomolecular Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
The
review
aims
to
provide
a
clear
picture
of
the
possible
electron
transfer
pathways,
electrochemical
behavior
different
N-heterocycles,
and
functionalization
reagents
achieve
desired
functionalization/modification
N-heterocycles.
