Electrochemical Oxidation of Primary Amines for the Synthesis of Benzimidazole, Benzothiazole, Quinazolinone, and Quinoxaline
The Journal of Organic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Июнь 1, 2025
The
development
of
green
and
efficient
methods
for
the
construction
N-heterocyclic
frameworks
has
attracted
considerable
attention
in
organic
synthesis.
In
this
work,
an
electrochemical
oxidative
cyclization
primary
amines
synthesis
benzimidazole,
benzothiazole,
quinazolinone,
quinoxaline
been
developed.
This
catalyst-
oxidant-free
strategy
demonstrates
good
functional
group
tolerance,
up
to
87%
yield
N-based
heterocycles
undivided
cell
under
open-air
conditions
is
easy
scale
up.
Язык: Английский
Cascade Electrochemical Aerobic Oxygenation of 2-Substituted Indoles and Electrochemical [5 + 3] Annulation with Amidines: Access to Eight-Membered Benzo[1,3,5]triazocin-6(5H)-ones
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(7), С. 4673 - 4683
Опубликована: Март 13, 2024
The
cascade
electrochemical
C3-selective
aerobic
oxygenation
of
2-substituted
indoles
and
[5
+
3]
annulation
with
amidines
through
an
undivided
cell
galvanostatic
method
employing
molecular
oxygen
"electricity"
as
green
oxidants
was
developed.
This
protocol
provides
efficient
direct
approach
to
eight-membered
benzo[1,3,5]triazocin-6(5H)-ones.
Mechanistic
studies
suggested
that
two
subsequent
processes
both
proceeded
radical
pathways.
Язык: Английский
Six-membered ring systems: Diazines and benzo derivatives
Progress in heterocyclic chemistry,
Год журнала:
2024,
Номер
unknown, С. 355 - 393
Опубликована: Янв. 1, 2024
PPh3-Mediated cascade reaction of 2-alkynylnitrobenzenes and 1,2-diaminoarenes for the construction of 2-aryl-3-(2-aminoaryl)quinoxalines
Xiaoming Liao,
Yao Xu,
Hui Fan
и другие.
New Journal of Chemistry,
Год журнала:
2023,
Номер
48(2), С. 733 - 737
Опубликована: Дек. 1, 2023
A
metal-free
strategy
to
2-aryl-3-(2-aminoaryl)quinoxalines
from
2-alkynylnitrobenzenes
and
1,2-diaminobenzenes
is
developed.
Язык: Английский