Valorization of Lignocellulosic Molecules through Homogeneous Ru‐Catalyzed C−C and C−N Bond Forming Reactions

ChemistrySelect, Год журнала: 2024, Номер 9(5)

Опубликована: Янв. 30, 2024

Abstract A sustainable upgrading of renewable bulk materials, obtained by decomposition biomass lignocellulose, could facilitate their use in the industrial production chemicals. Homogeneous ruthenium catalysis plays a fundamental role this area. The review deals with upgradation lignocellulosic molecules through formation new C−C and C−N bonds. Selected examples catalytic bond forming reactions reported until mid 2023, include: (a) dehydrogenative based couplings alcohols, (b) reductive amination carbonyl compounds, (c) direct C−H functionalization (hetero)aromatic compounds. These approaches fulfill requirements sustainability: application occurs without any previous substrate activation, thus reducing waste. New chemicals containing intrinsic molecular structure lignocellulose substrates, showed broad range applications: green fuels, hydrogen carriers, monomers polymers, intermediates fine pharmaceuticals. results discussed inspire reader to improve valorization process, terms bio‐substrate scope as well product complexity, more strategic applications methods.

Язык: Английский

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Regioselective Ring Opening of Epoxide with Alcohols: A Selective Route to α‐Alkylated Ketones and β‐Alkylated Secondary Alcohols

ChemCatChem, Год журнала: 2024, Номер 16(16)

Опубликована: Апрель 17, 2024

Abstract Herein, we demonstrated an effective protocol for the regioselective ring opening of epoxides with alcohols. By following this strategy, both α‐alkylated ketones and β‐alkylated secondary alcohols were selectively obtained by changing reaction parameters. Compared to previously reported protocols, methodology was operated using considerably lower base at temperature. Notably, a wide array substrates tolerance different functional groups demonstrated. A series control experiments deuterium‐labelling performed understand catalytic process.

Язык: Английский

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Green Synthesis of Diphenyl‐Substituted Alcohols Via Radical Coupling of Aromatic Alcohols Under Transition‐Metal‐Free Conditions

ChemistryOpen, Год журнала: 2024, Номер 13(12)

Опубликована: Авг. 22, 2024

Alcohols are common alkylating agents and starting materials alternative to harmful alkyl halides. In this study, a simple, benign efficient pathway was developed synthesize 1,3-diphenylpropan-1-ols via the β-alkylation of 1-phenylethanol with benzyl alcohols. Unlike conventional borrowing hydrogen processes in which alcohols were activated by transition-metal catalyzed dehydrogenation, work, t-BuONa suggested be dual-role reagent, namely, both base radical initiator, for coupling aromatic The cross-coupling reaction readily proceeded under transition metal-free conditions an inert atmosphere, affording 1,3-diphenylpropan-1-ol excellent yield. A good functional group tolerance observed, leading production various phenyl-substituted propan-1-ol derivatives moderate-to-good yields. mechanistic studies proposed that could involve formation reactive anions base-mediated deprotonation single electron transfer.

Язык: Английский

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Selective C- and N-Methylation of Secondary Alcohols and Nitroaromatics with Methanol Catalyzed by a New Ru(II)-Azo Complex

Organometallics, Год журнала: 2024, Номер unknown

Опубликована: Окт. 24, 2024

Язык: Английский

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