Unveiling the role of Lewis bases in cascade furan Diels–Alder cycloadditions: asymmetric synthesis of polycyclic quinazolinones DOI
Yuhan Li, Dongyi Zhang, Zhonglin Wei

и другие.

Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(19), С. 5488 - 5494

Опубликована: Янв. 1, 2024

A Lewis base catalyzed asymmetric substitution/IMDAF reaction for the synthesis of polycyclic quinazolinones has been developed. The key role in IMDAF process unveiled.

Язык: Английский

(NH4)2S2O8 promoted tandem radical cyclization of quinazolin-4(3H)-ones with oxamic acids for the construction of fused quinazolinones under metal-free conditions DOI
Shenyuan Gao, Menglu Cai, Gang Xu

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер 22(11), С. 2241 - 2251

Опубликована: Янв. 1, 2024

A novel cascade radical addition/cyclization reaction of non-activated olefins and oxamic acids has been proposed.

Язык: Английский

Процитировано

5
Photoinduced palladium-catalyzed radical addition/cyclization of unactivated alkenes with alkyl halides toward alkylated ring-fused quinazolinones DOI

Lixin Liu,

J.‐T. HUANG,

Yuanhua Li

и другие.

Journal of Organometallic Chemistry, Год журнала: 2024, Номер 1008, С. 123066 - 123066

Опубликована: Фев. 18, 2024

Язык: Английский

Процитировано

3
Acid-catalyzed radical tandem alkylation/cyclization of unactivated alkenes with ketones: Access to ketoalkyl-substituted quinazolinone derivatives DOI

Jian-Li Wu,

Meng Yan,

Lulu Fan

и другие.

Tetrahedron, Год журнала: 2024, Номер 162, С. 134085 - 134085

Опубликована: Июнь 11, 2024

Язык: Английский

Процитировано

2
Photoredox/HAT-Catalyzed Intramolecular Hydrocyclization of Alkenes toward 2,3-Fused Quinazolinones and Dihydroquinazolinones DOI
Dong Li, Xiaoqing Wang,

Yanhui Gou

и другие.

Organic Letters, Год журнала: 2024, Номер unknown

Опубликована: Окт. 2, 2024

New photochemical approaches to 2,3-fused quinazolinones and dihydroquinazolinones are disclosed. The intramolecular hydrocyclization proceeds in moderate excellent yields across diverse alkenes with high regioselectivity diastereocontrol. Mechanistic studies indicated that the radical cascade processes involve thiophenol acting as single-electron transfer hydrogen atom reagents. success of gram-scale synthesis proves strategy can be used for practical applications.

Язык: Английский

Процитировано

1
Metal-free Synthesis of 1,1-Dimethyl-2,2,2-trifluoroethyl Substituted Quinazolinones via Tandem Radical Cyclization of Quinazolin-4(3H)-ones with 3,3,3-Trifluoro-2,2-dimethylpropanoic acid DOI
Shenyuan Gao, Menglu Cai,

Xiaozhong Wang

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер 22(31), С. 6376 - 6384

Опубликована: Янв. 1, 2024

A metal-free (NH

Язык: Английский

Процитировано

0
Visible-light-induced selective hydrolipocyclization and silylation of alkenes: access to ring-fused quinazolin-4(3H)-ones and their silicon-substituted derivatives DOI
Shoucai Wang, Ziren Chen, Fei Xue

и другие.

Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(21), С. 6019 - 6025

Опубликована: Янв. 1, 2024

A visible-light-induced intermolecular silylation and hydrolipocyclization using hydrosilane as the hydrogen silicon source has been developed, which provided an efficient pathway for synthesis of organosilanes polycyclic quinazolinones.

Язык: Английский

Процитировано

0
Unveiling the role of Lewis bases in cascade furan Diels–Alder cycloadditions: asymmetric synthesis of polycyclic quinazolinones DOI
Yuhan Li, Dongyi Zhang, Zhonglin Wei

и другие.

Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(19), С. 5488 - 5494

Опубликована: Янв. 1, 2024

A Lewis base catalyzed asymmetric substitution/IMDAF reaction for the synthesis of polycyclic quinazolinones has been developed. The key role in IMDAF process unveiled.

Язык: Английский

Процитировано

0