Green Synthesis and Catalysis,
Год журнала:
2024,
Номер
unknown
Опубликована: Июль 1, 2024
A
straightforward
and
valuable
approach
for
the
synthesis
of
1,4-oxathiins
has
been
developed
via
[3
+
3]
annulation
pyridinium
1,4-zwitterionic
thiolates
with
iodonium
ylides.
C–S
C–O
bonds
were
formed
in
one
pot
manner
this
transformation,
which
features
readily
available
substrates,
excellent
tolerance
functional
groups
mild
reaction
conditions.
It
would
be
great
value
construction
biological
pharmacological
activity.
Chemical Reviews,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 13, 2024
Hypervalent
iodine(III)
compounds
have
found
wide
application
in
modern
organic
chemistry
as
environmentally
friendly
reagents
and
catalysts.
iodine
are
commonly
used
synthetically
important
halogenations,
oxidations,
aminations,
heterocyclizations,
various
oxidative
functionalizations
of
substrates.
Iodonium
salts
arylating
reagents,
while
iodonium
ylides
imides
excellent
carbene
nitrene
precursors.
Various
derivatives
benziodoxoles,
such
azidobenziodoxoles,
trifluoromethylbenziodoxoles,
alkynylbenziodoxoles,
alkenylbenziodoxoles
group
transfer
the
presence
transition
metal
catalysts,
under
metal-free
conditions,
or
using
photocatalysts
photoirradiation
conditions.
Development
hypervalent
catalytic
systems
discovery
highly
enantioselective
reactions
chiral
represent
a
particularly
recent
achievement
field
chemistry.
Chemical
transformations
promoted
by
many
cases
unique
cannot
be
performed
any
other
common,
non-iodine-based
reagent.
This
review
covers
literature
published
mainly
last
7-8
years,
between
2016
2024.
Chemistry - A European Journal,
Год журнала:
2024,
Номер
30(31)
Опубликована: Март 28, 2024
Abstract
Photoinduced
aryl
radical
generation
is
a
powerful
strategy
in
organic
synthesis
that
facilitates
the
formation
of
diverse
carbon‐carbon
and
carbon‐heteroatom
bonds.
The
synthetic
applications
photoinduced
complex
compounds,
including
natural
products,
physiologically
significant
molecules,
functional
materials,
have
received
immense
attention.
An
overview
current
developments
production
methods
their
uses
given
this
article.
A
generalized
idea
how
to
choose
reagents
approach
for
radicals
described,
along
with
techniques
associated
mechanistic
insights.
Overall,
article
offers
critical
assessment
results
as
well
selection
reaction
parameters
specific
context
cascades,
cross‐coupling
reactions,
functionalization,
selective
C−H
functionalization
substrates.
Chinese Journal of Organic Chemistry,
Год журнала:
2023,
Номер
43(12), С. 4213 - 4213
Опубликована: Янв. 1, 2023
Benzoxazines
are
important
motif
in
pharmaceuticals
and
functional
molecules.A
visible-light
induced
photocatalytic
strategy
for
the
synthesis
of
difluoroethyl
benzoxazines
with
organo-photocatalyst
was
developed.In
present
protocol,
a
series
olefinic
amides
can
be
transferred
to
difluoroethylated
via
oxydifluoromethylation
CF2HSO2Na
as
difluoromethylating
reagent,
which
is
easily
operated
good
group
tolerant.
Chemical Reviews,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 7, 2025
Constructing
chemical
bonds
under
green
sustainable
conditions
has
drawn
attention
from
environmental
and
economic
perspectives.
The
dissociation
of
(hetero)aryl-halide
is
a
crucial
step
most
arylations
affording
(hetero)arene
derivatives.
Herein,
we
summarize
the
(hetero)aryl
halides
activation
enabling
direct
(hetero)arylation
trapping
reagents
construction
highly
functionalized
(hetero)arenes
benign
conditions.
strategies
for
aryl
iodides
are
classified
into
(a)
hypervalent
iodoarene
followed
by
functionalization
thermal/photochemical
conditions,
(b)
aryl-I
bond
in
presence
bases
with/without
organic
catalysts
promoters,
(c)
photoinduced
presence/absence
organophotocatalysts,
(d)
electrochemical
direct/indirect
electrolysis
mediated
organocatalysts
mediators
acting
as
electron
shuttles,
(e)
electrophotochemical
redox-active
organocatalysts.
These
modes
result
exhibiting
diverse
reactivity
formal
cations/radicals/anions
aryne
precursors.
coupling
these
reactive
intermediates
with
leads
to
facile
selective
formation
C-C
C-heteroatom
bonds.
ecofriendly,
inexpensive,
functional
group-tolerant
offer
alternatives
transition
metal-based
catalysis.
Chinese Journal of Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 20, 2025
Comprehensive
Summary
Herein,
it
is
reported
that
the
aryl
radicals
derived
from
thianthrenium
salts
are
used
as
coupling
partner
in
arylation
reactions
of
isocyanides,
simultaneously
initiators
for
formation
alkyl
and
phosphoryl
ethers
diarylphosphine
oxides.
This
cascade
cyclization
reaction
leads
to
diverse
arylated,
alkylated
phosphorylated
heteroaromatic
compounds.
Notably,
this
transformation
can
be
achieved
without
aid
metals
or
photocatalysts,
exhibiting
a
wide
substrate
applicability
operational
simplicity.
Mechanistic
studies
suggest
involvement
radical
processes
electron
donor‐acceptor
(EDA)
complexes
transformation.
Organic Chemistry Frontiers,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
We
reported
the
first
example
of
visible-light-induced
radical
cascade
cyclization
2-isocyanobiaryls
via
1,5-HAT,
which
is
characterized
by
broad
substrate
scope,
excellent
functional
group
compatibility
and
no
requirement
any
metals
base.
Abstract
4‐CzIPN
is
a
traditional
electron
donor
and
acceptor
fluorophore
that
uses
carbazolyl
as
an
donating
dicyanobenzene
withdrawing
source.
Its
broad
redox
potential,
high
chemical
resistance
wide
applicability
makes
it
unique
metal‐free
photocatalyst.
This
study
summarizes
the
recent
development
of
photoredox
catalyst
for
variety
heterocyclic
construction
over
last
four
years
(2021‐2024).
Asian Journal of Organic Chemistry,
Год журнала:
2023,
Номер
12(11)
Опубликована: Сен. 22, 2023
Abstract
Phenanthridines
are
a
privileged
heterocyclic
compound
that
exists
in
many
natural
products
and
has
been
known
to
exhibit
variety
of
pharmacological
properties.
In
the
last
few
decades,
an
incredible
development
taken
place
synthesise
this
scaffold.
regard,
2‐isocyanobiphenyl
become
one
most
exploited
substrates
allow
direct
formation
phenanthridine
derivatives
under
various
novel
conventional
methods.
The
present
review
provides
overview
synthetic
approaches
for
preparation
phenanthridine,
their
form
2‐isocyanobiphenyls′′.
Chinese Journal of Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 10, 2024
Comprehensive
Summary
A
visible‐light‐induced
decarboxylative
radical
cascade
cyclization
reaction
between
N
‐(2‐cyanoaryl)‐acrylamides
and
alkyl
‐(acyloxy)phthalimide
(NHPI
esters)
for
the
construction
of
phenanthridine
derivatives
has
been
developed.
This
approach
utilizes
lithium
iodide
(LiI)
triphenylphosphine
(PPh
3
)
as
redox
catalysts
is
produced
through
photoactivation
electron
donor‐acceptor
(EDA)
complex.
series
primary,
secondary,
tertiary
alkyl‐substituted
phenanthridines
are
prepared
in
up
to
82%
yield
without
transition‐metal
catalysts,
chemical
oxidants,
or
metal‐/organic
dye‐based
photocatalysts.
The Journal of Organic Chemistry,
Год журнала:
2023,
Номер
88(24), С. 17322 - 17329
Опубликована: Дек. 4, 2023
A
visible-light-induced
annulation/thiolation
of
2-isocyanobiaryls
with
dialkyl(aryl)disulfides
has
been
established,
delivering
a
sustainable
and
atom-economic
route
to
6-organoylthiophenanthridines
wild
functional
group
tolerance
good
excellent
yields
under
oxidant-,
base-,
transition-metal-free
conditions.
