PPh3-Mediated cascade reaction of 2-alkynylnitrobenzenes and 1,2-diaminoarenes for the construction of 2-aryl-3-(2-aminoaryl)quinoxalines DOI

Xiaoming Liao,

Yao Xu,

Hui Fan

et al.

New Journal of Chemistry, Journal Year: 2023, Volume and Issue: 48(2), P. 733 - 737

Published: Dec. 1, 2023

A metal-free strategy to 2-aryl-3-(2-aminoaryl)quinoxalines from 2-alkynylnitrobenzenes and 1,2-diaminobenzenes is developed.

Language: Английский

Electrochemical Oxidation of Primary Amines for the Synthesis of Benzimidazole, Benzothiazole, Quinazolinone, and Quinoxaline DOI
J. H. Zou, Jundong Xu, Lijun Li

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: June 1, 2025

The development of green and efficient methods for the construction N-heterocyclic frameworks has attracted considerable attention in organic synthesis. In this work, an electrochemical oxidative cyclization primary amines synthesis benzimidazole, benzothiazole, quinazolinone, quinoxaline been developed. This catalyst- oxidant-free strategy demonstrates good functional group tolerance, up to 87% yield N-based heterocycles undivided cell under open-air conditions is easy scale up.

Language: Английский

Citations

0
Cascade Electrochemical Aerobic Oxygenation of 2-Substituted Indoles and Electrochemical [5 + 3] Annulation with Amidines: Access to Eight-Membered Benzo[1,3,5]triazocin-6(5H)-ones DOI

Weihui Zhuang,

Fengyi Xiao,

Yumei Chen

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(7), P. 4673 - 4683

Published: March 13, 2024

The cascade electrochemical C3-selective aerobic oxygenation of 2-substituted indoles and [5 + 3] annulation with amidines through an undivided cell galvanostatic method employing molecular oxygen "electricity" as green oxidants was developed. This protocol provides efficient direct approach to eight-membered benzo[1,3,5]triazocin-6(5H)-ones. Mechanistic studies suggested that two subsequent processes both proceeded radical pathways.

Language: Английский

Citations

1
Six-membered ring systems: Diazines and benzo derivatives DOI

K. Alison Rinderspacher

Progress in heterocyclic chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 355 - 393

Published: Jan. 1, 2024

Citations

0
PPh3-Mediated cascade reaction of 2-alkynylnitrobenzenes and 1,2-diaminoarenes for the construction of 2-aryl-3-(2-aminoaryl)quinoxalines DOI

Xiaoming Liao,

Yao Xu,

Hui Fan

et al.

New Journal of Chemistry, Journal Year: 2023, Volume and Issue: 48(2), P. 733 - 737

Published: Dec. 1, 2023

A metal-free strategy to 2-aryl-3-(2-aminoaryl)quinoxalines from 2-alkynylnitrobenzenes and 1,2-diaminobenzenes is developed.

Language: Английский

Citations

0