Development of novel transition metal-catalyzed synthetic approaches for the synthesis of a dihydrobenzofuran nucleus: a review
RSC Advances,
Год журнала:
2024,
Номер
14(21), С. 14539 - 14581
Опубликована: Янв. 1, 2024
The
synthesis
of
dihydrobenzofuran
scaffolds
bears
pivotal
significance
in
the
field
medicinal
chemistry
and
organic
synthesis.
These
heterocyclic
hold
immense
prospects
owing
to
their
significant
pharmaceutical
applications
as
they
are
extensively
employed
essential
precursors
for
constructing
complex
frameworks.
Their
versatility
importance
make
them
an
interesting
subject
study
researchers
scientific
community.
While
exploring
synthesis,
have
unveiled
various
novel
efficient
pathways
assembling
core.
In
wake
extensive
data
being
continuously
reported
each
year,
we
outlined
recent
updates
(post
2020)
on
methodological
accomplishments
employing
catalytic
role
several
transition
metals
forge
functionalities.
Язык: Английский
Asymmetric Intramolecular Amination Catalyzed with Cp*Ir-SPDO via Nitrene Transfer for Synthesis of Spiro-Quaternary Indolinone
Journal of the American Chemical Society,
Год журнала:
2024,
Номер
146(28), С. 18841 - 18847
Опубликована: Июль 8, 2024
An
asymmetric
intramolecular
spiro-amination
to
high
steric
hindering
Язык: Английский
Asymmetric Synthesis of Hydrodibenzofurans from Norcaradienes: Kinetic Resolution via [3 + 2] Cycloaddition with Quinones
Organic Letters,
Год журнала:
2024,
Номер
26(18), С. 3844 - 3849
Опубликована: Апрель 25, 2024
The
catalytic
asymmetric
[3
+
2]
cycloaddition
of
racemic
norcaradienes
with
quinones
to
construct
multicyclic
hydrodibenzofurans
was
achieved
by
the
use
chiral
N,N′-dioxide/metal
complex
catalysts.
Kinetic
resolution
accompanied
partial
racemization
occurred,
and
one
enantiomer
in
prior
acted
as
C2
synthon
participate
diastereoselective
cycloaddition.
An
enantiodivergent
synthesis
via
a
switch
metal
ions
observed
when
naphthoquinone
used
partner.
DFT
calculations
revealed
profiles
processes.
Язык: Английский
Au(PPh3)Cl/AgOTf/TsOH-Catalyzed Cascade Reaction between 1-(2-Hydroxyphenyl)-propargyl Alcohols and β-Oxoketones (Amides, Acid): Diastereoselective Construction of cis-3a,8a-Dihydrofuro[2,3-b]benzofuran Framework
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 20, 2024
In
the
Au(PPh
Язык: Английский
Annulations involving p-benzoquinones: stereoselective synthesis of fused, spiro and bridged molecules
New Journal of Chemistry,
Год журнала:
2024,
Номер
48(18), С. 8243 - 8276
Опубликована: Янв. 1, 2024
The
present
review
summarizes
the
recent
advances
(2018–2023)
in
stereoselective
annulation
involving
p
-benzoquinones
for
construction
of
fused,
spiro
and
bridged/cage
frameworks.
Язык: Английский
De novo synthesis of atropisomeric benzofurans via Cu/SPDO complex catalyzed asymmetric formal [3 + 2] annulation
Science China Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 9, 2024
Язык: Английский
Novel transition metal-free synthetic protocols toward the construction of 2,3-dihydrobenzofurans: a recent update
Frontiers in Chemistry,
Год журнала:
2024,
Номер
12
Опубликована: Дек. 13, 2024
2,3-Dihydrobenzofurans
are
noteworthy
scaffolds
in
organic
and
medicinal
chemistry,
constituting
the
structural
framework
of
many
varied
medicinally
active
compounds.
Moreover,
a
diverse
variety
biologically
potent
natural
products
also
contain
this
heterocyclic
nucleus.
Reflecting
on
wide
biological
substantiality
dihydrobenzofurans,
several
innovative
facile
synthetic
developments
evolving
to
achieve
these
heterocycles.
This
review
summarizes
transition-metal-free,
efficient,
novel
pathways
toward
constructing
dihydrobenzofuran
nucleus
established
after
2020.
Язык: Английский