Synthesis of Primary and Secondary Amines via Electrochemical Reduction of Hydrazines DOI

Dong Wang,

Qiulu Wang,

Mingxia Liu

и другие.

Organic Letters, Год журнала: 2024, Номер 26(51), С. 11123 - 11128

Опубликована: Дек. 13, 2024

We herein introduce an electrochemical route for the N–N bond cleavage of hydrazines. This mild and green methodology utilized readily available mono- 1,1-disubstituted hydrazines or their HCl salts as starting materials to access a broad scope primary secondary amines in high yields. The mechanistic investigation suggests that amine product is formed by consecutive SET reduction, utilization hydrazine salt important providing sufficient conductivity acidity facilitate this reaction.

Язык: Английский

Synthesis of Primary and Secondary Amines via Electrochemical Reduction of Hydrazines DOI

Dong Wang,

Qiulu Wang,

Mingxia Liu

и другие.

Organic Letters, Год журнала: 2024, Номер 26(51), С. 11123 - 11128

Опубликована: Дек. 13, 2024

We herein introduce an electrochemical route for the N–N bond cleavage of hydrazines. This mild and green methodology utilized readily available mono- 1,1-disubstituted hydrazines or their HCl salts as starting materials to access a broad scope primary secondary amines in high yields. The mechanistic investigation suggests that amine product is formed by consecutive SET reduction, utilization hydrazine salt important providing sufficient conductivity acidity facilitate this reaction.

Язык: Английский

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