Radical 1,3-Hydrosulfonylation of Vinyldiazo Compounds with Sulfinyl Sulfones

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Фев. 4, 2025

Sulfinyl sulfones, as high-valence sulfurization reagents, are widely used to assemble sulfur sources on carbon skeletons, such one-, two-, and four-carbon synthons, access organosulfur compounds. However, their reaction with three-carbon synthons has remained a mystery until now. We report here radical 1,3-hydrosulfonylation of vinyldiazo compounds sulfinyl sulfones. This not only represents the first example sulfones but also opens up application in monofunctionalization.

Язык: Английский

Metal-free iodosulfonylation of alkynes to access (E)-β-iodovinyl sulfones in water

Organic & Biomolecular Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

We report a metal-free iodosulfonylation of alkynes in water at room temperature, which efficiently produces ( E )-β-iodovinyl sulfones good to excellent yields with high regio- and stereoselectivity.

Язык: Английский