
Green Synthesis and Catalysis, Год журнала: 2025, Номер unknown
Опубликована: Март 1, 2025
Язык: Английский
Green Synthesis and Catalysis, Год журнала: 2025, Номер unknown
Опубликована: Март 1, 2025
Язык: Английский
Organic Letters, Год журнала: 2019, Номер 21(12), С. 4812 - 4815
Опубликована: Июнь 13, 2019
A novel ruthenium-catalyzed [5 + 1] annulation of 2-alkenylanilines with sulfoxonium ylides was developed for the rapid assembly highly functionalized quinolines. This new catalytic process employs challenging but synthetically ideal free amino functionality to achieve alkenyl C–H activation as one-carbon coupling partners. Various 2-acylquinolines could be obtained good yields and excellent functional group tolerance. Moreover, potential synthetic application this methodology exemplified by several chemical transformations.
Язык: Английский
Процитировано
105Chemical Communications, Год журнала: 2019, Номер 55(28), С. 4039 - 4042
Опубликована: Янв. 1, 2019
Selective synthesis of indoles and quinazolines was achieved through a precise control C–H activation/annulation by changing additives.
Язык: Английский
Процитировано
101Organic Letters, Год журнала: 2019, Номер 21(17), С. 6653 - 6657
Опубликована: Авг. 19, 2019
A rhodium-catalyzed annulation between aroyl sulfoxonium ylides and anthranils has been developed to synthesize 10H-indolo[1,2-a]indol-10-one derivatives. This reaction started with an unpredented (4 + 1) toward N-(2-formylphenyl) indolones, proceeding the sequential ortho-amination of C–H bond in by insertion N–H carbene. Finally, Aldol condensation constructed second indole ring. procedure features formation two C–N bonds one C═C pot.
Язык: Английский
Процитировано
87Tetrahedron, Год журнала: 2021, Номер 101, С. 132478 - 132478
Опубликована: Окт. 8, 2021
Язык: Английский
Процитировано
71Asian Journal of Organic Chemistry, Год журнала: 2022, Номер 11(4)
Опубликована: Март 23, 2022
Abstract In recent years, the transition‐metal‐catalyzed functionalization reactions of sulfoxonium ylides have been explored extensively because their usefulness as carbene‐transfer agents, since they can produce metal carbenes through catalysis. Moreover, are safer and advantages simple handling good stability over other counterparts like diazo‐compounds. This review article attempts to highlight advances in metal‐catalyzed C−H ylides.
Язык: Английский
Процитировано
41Organic Letters, Год журнала: 2020, Номер 22(4), С. 1504 - 1509
Опубликована: Фев. 11, 2020
An unprecedented copper-catalyzed reaction of sulfoxonium ylides and anthranils is reported that enables an easy access to 2,3-diaroylquinolines through a [4+1+1] annulation. Copper-catalyzed homocoupling provided α,α,β-tricarbonyl ylides, which provides strategy extend the carbon chain C–C bond formation. The utility products as well mechanistic details process are presented.
Язык: Английский
Процитировано
61Organic Letters, Год журнала: 2019, Номер 21(16), С. 6366 - 6369
Опубликована: Июль 30, 2019
A rhodium(III)-catalyzed C–H acylmethylation of tridentate [2,2′-bipyridine]-6-carboxamides was developed. variety could be monoalkylated exclusively at the C3 position with sulfoxonium ylides as carbene precursors, giving 3-alkylated products in high yields. This protocol proceeds through a rollover cyclometalation pathway, has broad range scope substrates, and exhibits excellent functional group tolerance.
Язык: Английский
Процитировано
56Organic Letters, Год журнала: 2020, Номер 22(4), С. 1375 - 1379
Опубликована: Фев. 3, 2020
The synthesis of indanone derivatives by the Rh(III)-catalyzed reaction α-carbonyl sulfoxonium ylides with activated alkenes is reported. shows a high tolerance for functional groups and furnishes variety substituted via formal [4 + 1] cycloaddition. Highly stable were used as substrates in this C-H functionalization, their bifunctional character could be effectively exploited using Rh(III) catalysis sequential double C-C bond formation. Based on mechanistic studies including deuterium-labeling experiments, proposed to proceed follows: oxidative alkenylation β-hydride elimination, readdition H-Rh species, 1,2-carbon shift elimination DMSO, protonation.
Язык: Английский
Процитировано
56Organic Letters, Год журнала: 2022, Номер 24(5), С. 1146 - 1151
Опубликована: Фев. 3, 2022
A novel photo-thermo-mechanochemical approach to assembling quinolines catalyzed by iron(II) phthalocyanine has been realized for the first time. This transformation features a cost-efficient catalytic system and operational simplicity, is free of solvent, shows good substrate tolerance, providing green alternative existing thermal approaches. Mechanistic experiments demonstrate that in-situ-formed secondary amine may be key intermediate further cyclization/aromatization process.
Язык: Английский
Процитировано
30Organic Letters, Год журнала: 2019, Номер 21(13), С. 5273 - 5276
Опубликована: Июнь 26, 2019
We have presented a simple and new method for the divergent assembly of furoxans isoxazoles in which [2 + 1 1] annulation reaction sulfoxonium ylides is reported first time. When was performed using tBuONO as nitrogen source without metal catalyst, desired were obtained decent yields with wide substrate scope. Isoxazoles bearing three carbonyl groups achieved when conducted Cu(TFA)2 catalyst.
Язык: Английский
Процитировано
50