Insect Molecular Biology,
Год журнала:
2022,
Номер
32(1), С. 46 - 55
Опубликована: Окт. 10, 2022
Abstract
Insects
are
the
most
widely
distributed
and
successful
animals
on
planet.
A
large
number
of
insects
capable
flight
with
functional
wings.
Wing
expansion
is
an
important
process
for
to
achieve
wings
after
eclosion
healthy
genital
morphology
crucial
adult
reproduction.
Myofilaments
units
that
constitute
sarcomeres
trigger
muscle
contraction.
Here,
we
identified
four
myofilament
proteins,
including
Myosin,
Paramyosin,
Tropomyosin
Troponin
T,
from
wing
pads
nymphs
in
American
cockroach,
Periplaneta
americana
.
RNAi‐mediated
knockdown
Myosin
,
Paramyosin
T
early
stage
final
instar
caused
a
severely
curly
phenotype
imaginal
moult,
especially
groups,
indicating
these
proteins
involved
controlling
behaviours
during
nymph‐adult
transition.
In
addition,
resulted
abnormal
external
genitalia,
ovulation
failure,
affected
male
accessory
gland
development.
Interestingly,
expression
genes
was
induced
by
methoprene,
juvenile
hormone
(JH)
analogue,
decreased
depletion
JH
receptor
gene
Met
Altogether,
have
determined
play
role
promoting
maintaining
genitalia
morphology,
their
signalling.
Our
data
reveal
novel
mechanism
which
regulated
myofilaments
functions
morphology.
International Journal of Molecular Sciences,
Год журнала:
2021,
Номер
22(4), С. 1940 - 1940
Опубликована: Фев. 16, 2021
Leucokinins
(LKs)
constitute
a
family
of
neuropeptides
identified
in
numerous
insects
and
many
other
invertebrates.
LKs
act
on
G-protein-coupled
receptors
that
display
only
distant
relations
to
known
receptors.
In
adult
Drosophila,
26
neurons/neurosecretory
cells
three
main
types
express
LK.
The
four
brain
interneurons
are
two
types,
these
implicated
several
important
functions
the
fly's
behavior
physiology,
including
feeding,
sleep-metabolism
interactions,
state-dependent
memory
formation,
as
well
modulation
gustatory
sensitivity
nociception.
22
neurosecretory
(abdominal
LK
neurons,
ABLKs)
abdominal
neuromeres
co-express
diuretic
hormone
(DH44),
together,
regulate
water
ion
homeostasis
associated
stress
food
intake.
Drosophila
larvae,
neurons
modulate
locomotion,
escape
responses
aspects
ecdysis
behavior.
A
set
lateral
cells,
ALKs
(anterior
neurons),
but
inconsistently
so
adults.
These
homeostasis,
drinking,
specific
role
is
not
yet
known.
This
review
summarizes
data
embryonic
lineages
functional
roles
individual
neuron
interactions
with
peptidergic
systems,
orchestrating
Journal of Agricultural and Food Chemistry,
Год журнала:
2024,
Номер
72(18), С. 10304 - 10313
Опубликована: Апрель 24, 2024
Neuropeptides
are
involved
in
many
biological
processes
insects.
However,
it
is
unclear
what
role
neuropeptides
play
Spodoptera
litura
adaptation
to
phytochemical
flavone.
In
this
study,
63
neuropeptide
precursors
from
48
gene
families
were
identified
S.
litura,
including
two
F
genes
(NPFs).
NPFs
played
a
positive
feeding
regulation
because
knockdown
of
decreased
larval
diet
intake.
larvae
reduced
flavone
intake
by
downregulating
NPFs.
Conversely,
the
was
increased
if
treated
with
NPF
mature
peptides.
The
receptor
(NPFR)
susceptible
fluctuation
NPFR
mediated
signaling
interacting
regulate
conclusion,
study
suggested
that
regulated
promote
flavone,
which
contributed
understanding
insect
mechanisms
host
plants
and
provide
more
potential
pesticidal
targets
for
pest
control.
Insect Science,
Год журнала:
2023,
Номер
31(3), С. 773 - 791
Опубликована: Сен. 9, 2023
Abstract
Neuropeptides
are
crucial
in
regulation
of
a
rich
variety
developmental,
physiological,
and
behavioral
functions
throughout
the
life
cycle
insects.
Using
an
integrated
approach
multiomics,
we
identified
neuropeptide
precursors
greater
wax
moth
Galleria
mellonella
,
which
is
harmful
pest
honeybee
hives
with
worldwide
distribution.
Here,
total
63
67
were
predicted
annotated
G.
genome
transcriptome,
40
confirmed
peptidome.
Interestingly,
12
precursor
genes
present
but
absent
honeybees,
may
be
potential
novel
pesticide
target
sites.
Honeybee
contaminated
heavy
metals
such
as
lead,
enabling
its
bioaccumulation
bodies
through
food
chain,
performed
transcriptome
sequencing
to
analyze
effects
Pb
stress
on
mRNA
expression
level
precursors.
After
treatment
by
Pb,
F1
was
found
significantly
downregulated,
implying
that
this
might
associated
responding
metal
.
This
study
comprehensively
discussed
insect
neuropeptides,
example
The
results
valuable
for
future
elucidation
how
neuropeptides
regulate
physiological
contribute
our
understanding
insect's
environmental
plasticity
identify
new
biomarkers
assess
toxicity
Scientific Reports,
Год журнала:
2022,
Номер
12(1)
Опубликована: Июнь 14, 2022
Abstract
Neuropeptides
and
neuropeptide
receptors
are
crucial
regulators
to
insect
physiological
processes.
The
21.0
Gb
bases
were
obtained
from
Illumina
sequencing
of
two
libraries
representing
the
female
male
heads
Phauda
flammans
(Walker)
(Lepidoptera:
Phaudidae),
which
is
a
diurnal
defoliator
ficus
plants
usually
outbreaks
in
south
south-east
Asia,
identify
differentially
expressed
genes,
neuropeptides
receptor
whose
tissue
expressions
also
evaluated.
In
total,
99,386
unigenes
obtained,
156
up-regulated
61
down-regulated
genes
detected.
Fifteen
(i.e.,
F1b,
Ast,
NP1,
IMF,
Y,
BbA1,
CAP2b,
NPLP1,
SIF,
CCH2,
NP28,
NP3,
PDP3,
ARF2
SNPF)
66
(e.g.,
A2-1,
FRL2,
A32-1,
A32-2,
FRL3,
etc.)
identified
well-clustered
with
other
lepidopteron
.
This
first
sequencing,
identification
P.
provides
valuable
information
regarding
molecular
basis
The Journal of Comparative Neurology,
Год журнала:
2022,
Номер
530(18), С. 3126 - 3156
Опубликована: Авг. 29, 2022
Abstract
The
Madeira
cockroach
Rhyparobia
maderae
is
a
nocturnal
insect
and
prominent
model
organism
for
the
study
of
circadian
rhythms.
Its
master
clock,
controlling
locomotor
activity
sleep–wake
cycles,
located
in
accessory
medulla
optic
lobe.
For
better
understanding
brain
regions
controlled
by
clock
organization
this
general,
we
created
three‐dimensional
(3D)
reconstruction
all
neuropils
cerebral
ganglia
based
on
anti‐synapsin
anti‐γ‐aminobutyric
acid
immunolabeling
whole
mount
brains.
Forty‐nine
major
were
identified
three‐dimensionally
reconstructed.
Single‐cell
dye
fills
complement
data
provide
evidence
distinct
subdivisions
certain
areas.
Most
defined
fruit
fly
Drosophila
melanogaster
could
be
distinguished
as
well.
However,
some
do
not
exist
entities
while
others
are
lacking
fly.
In
addition
to
neuropils,
fiber
systems,
tracts,
commissures
reconstructed
served
important
landmarks
separating
Being
insect,
R.
an
new
species
growing
collection
3D
atlases
only
second
hemimetabolous
which
detailed
atlas
available.
This
will
highly
valuable
evolutionary
comparison
greatly
facilitate
addressing
areas
that
supervised
clock.
Journal of Proteome Research,
Год журнала:
2022,
Номер
21(10), С. 2247 - 2260
Опубликована: Сен. 15, 2022
Neuropeptides
are
signaling
molecules
that
regulate
almost
all
physiological
processes
in
animals.
Around
50
different
genes
for
neuropeptides
have
been
described
insects.
In
Coleoptera,
which
is
the
largest
insect
order
based
on
numbers
of
species,
knowledge
about
and
protein
hormones
still
limited
to
a
few
species.
Here,
we
analyze
neuropeptidomes
two
closely
related
tenebrionid
beetles:
Tenebrio
molitor
Zophobas
atratus─both
model
species
pharmacological
research.
We
combined
transcriptomic
mass
spectrometry
analyses
central
nervous
system
identify
neuropeptide-like
hormones.
Several
precursors
were
identified
T.
Z.
atratus,
40,
respectively,
confirmed
by
spectrometry.
This
study
provides
basis
further
functional
studies
as
well
design
environmentally
friendly
species-specific
peptidomimetics
be
used
biopesticides.
Furthermore,
since
has
become
accepted
European
Food
Safety
Authority
novel
food,
deeper
neuropeptidome
this
will
prove
useful
optimizing
production
programs
at
an
industrial
scale.
Amino Acids,
Год журнала:
2023,
Номер
55(11), С. 1641 - 1654
Опубликована: Окт. 26, 2023
Small
neuropeptides
from
the
corpora
cardiaca
are
responsible
in
cockroaches
for
mobilisation
of
trehalose
fat
body
into
haemolymph.
Such
hypertrehalosaemic
hormones
(HrTHs)
belong
to
large
family
insect
adipokinetic
(AKHs);
a
few
HrTHs
were
previously
sequenced
cockroaches,
and
genomic
and/or
transcriptomic
information
one
may
predict
genes
encoding
more
species.
Definite
elucidation
primary
structure
mature
peptide
with
putative
modifications
needs
analytical
chemical
methods.
In
current
study,
we
use
high-resolution
mass
spectrometry
coupled
liquid
chromatography
identify
unequivocally
13
cockroach
Either
genomic/transcriptomic
was
available
most
species
examined,
or
related
We
confirm
predicted
novel
sequences
find
hydroxyproline
modification
majority
peptides.
The
decapeptides
structurally
close
Bladi-HrTH,
which
is
found
all
seven
investigated
blaberid
subfamilies.
Bladi-HrTH
peptides
elicit
response
Periplaneta
americana,
blattid
cockroach.
