Angewandte Chemie,
Год журнала:
2023,
Номер
135(25)
Опубликована: Март 29, 2023
Abstract
We
report
an
aqueous
and
near‐infrared
(NIR)
light
mediated
photoinduced
reversible
addition–fragmentation
chain
transfer
(photo‐RAFT)
polymerization
system
catalyzed
by
tetrasulfonated
zinc
phthalocyanine
(ZnPcS
4
−
)
in
the
presence
of
peroxides.
Taking
advantage
its
fast
rates
high
oxygen
tolerance,
this
is
successfully
applied
for
preparation
hydrogels.
Exploiting
enhanced
penetration
NIR
light,
gelation
effectively
performed
through
non‐transparent
biological
barriers.
Notably,
RAFT
agents
embedded
these
hydrogel
networks
can
be
reactivated
on‐demand,
enabling
healing
under
irradiation.
In
contrast
to
minimal
capability
(<15
%)
hydrogels
prepared
free
radical
(FRP),
RAFT‐mediated
display
more
than
80
%
recovery
tensile
strength.
Although
healable
polymer
UV
blue
lights
have
already
been
established,
work
first
photochemistry
using
facilitating
thick
Nanoscale,
Год журнала:
2023,
Номер
15(48), С. 19486 - 19492
Опубликована: Янв. 1, 2023
Through
the
innovative
use
of
surface-displayed
horseradish
peroxidase,
this
work
explores
enzymatic
catalysis
both
bioRAFT
polymerization
and
bioATRP
to
prompt
polymer
synthesis
on
surface
Saccharomyces
cerevisiae
cells,
with
outperforming
polymerization.
The
resulting
modification
living
yeast
cells
synthetic
polymers
allows
for
a
significant
change
in
phenotype,
including
growth
profile,
aggregation
characteristics,
conjugation
non-native
enzymes
clickable
cell
surface,
opening
new
avenues
bioorthogonal
cell-surface
engineering.
ACS Macro Letters,
Год журнала:
2025,
Номер
unknown, С. 306 - 312
Опубликована: Фев. 21, 2025
Simultaneous
control
over
macromolecular
chain
topology,
molecular
weight,
and
dispersity
is
an
important
synthetic
goal
in
polymer
chemistry.
The
synthesis
of
well-defined
poly(methyl
acrylate)
star
polymers
with
ultrahigh
weights
(>106
g
mol-1)
tunable
dispersities
realized
for
the
first
time
via
blue
light-controlled
photoiniferter
polymerization
using
a
tetrafunctional
switchable
RAFT
agent
(SRA4).
spectroscopic
properties
activity
SRA4
can
be
reversibly
tuned
by
addition
acid/base.
For
example,
protonation
4-toluenesulfonic
acid
(TsOH)
leads
to
enhanced
UV-visible
light
absorption,
faster
rate,
lower
resulting
polymer.
Star
were
prepared
predicted
(Mn
≈
80-1550
kg
(Đ
1.8-1.2)
when
targeting
degrees
range
1000-20000
presence
varying
amounts
TsOH.
High
end-group
fidelity
such
was
confirmed
one-pot
extension
experiments,
which
afforded
series
pseudoblock
copolymers
controlled
dispersities.
Finally,
rotational
rheology
used
examine
effect
dispersity,
topology
(whether
linear
or
star-shaped)
on
solution
viscosity.
Journal of the American Chemical Society,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 4, 2025
Intracellular
radical
polymerizations
allow
for
the
direct
bioorthogonal
synthesis
of
various
synthetic
polymers
within
living
cells,
thereby
providing
a
pathway
to
polymer-modified
cells
or
fermentative
production
polymers.
Here,
we
show
that
Escherichia
coli
can
initiate
polymerization
acrylamide,
acrylic,
and
methacrylic
monomers
through
an
atom
transfer
reaction
triggered
by
activity
naturally
occurring
biomolecules
bacterial
cells.
were
confirmed
nuclear
magnetic
resonance
spectroscopy,
gel
permeation
chromatography
extracted
from
fluorescence
labeling
polymer
directly
inside
The
effect
on
cell
behavior
response
was
investigated
microscopy
flow
cytometry
techniques,
as
well
metabolic
membrane
integrity
assays.
resulting
products
are
cell-compatible,
indicated
high
viability
polymerized
In
cellulo
containing
fluorescent
dyes
also
achieved.
These
results
not
only
enhance
our
understanding
untapped
potential
catalysts
but
reveal
intracellular
based
initiators
tool
engineering
biology.
Chemical Communications,
Год журнала:
2024,
Номер
60(40), С. 5286 - 5289
Опубликована: Янв. 1, 2024
Host–guest
interaction
of
cucurbit[7]uril
is
used
to
adjust
the
reactivity
ketyl
radicals
and
benzoyl
radicals,
therefore
enhancing
aldehyde
selectivity
photo-induced
oxidation
benzyl
alcohol.
Angewandte Chemie International Edition,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 29, 2024
Abstract
Photomediated
Atom
Transfer
Radical
Polymerization
(photoATRP)
is
an
activator
regeneration
method,
which
allows
for
the
controlled
synthesis
of
well‐defined
polymers
via
light
irradiation.
Traditional
photoATRP
often
limited
by
need
high‐energy
ultraviolet
or
violet
light.
These
could
negatively
affect
control
and
selectivity
polymerization,
promote
side
reactions,
may
not
be
applicable
to
biologically
relevant
systems.
This
drawback
can
circumvented
introduction
catalytic
amount
photocatalysts,
absorb
visible
and/or
NIR
and,
therefore,
controlled,
regenerative
ATRP
performed
with
dual‐catalytic
cycle.
Herein,
a
critical
summary
recent
developments
in
field
dual‐catalysis
concerning
Cu‐catalyzed
provided.
Contributions
involved
species
are
examined
mechanistically,
followed
challenges
future
directions
towards
next
generation
advanced
functional
macromolecular
materials.
Angewandte Chemie,
Год журнала:
2023,
Номер
136(12)
Опубликована: Дек. 29, 2023
Abstract
Polymerization‐induced
self‐assembly
(PISA)
combines
polymerization
and
in
situ
of
block
copolymers
one
system
has
become
a
widely
used
method
to
prepare
copolymer
nanoparticles
at
high
concentrations.
The
persistence
polymers
the
environment
poses
huge
threat
ecosystem
represents
significant
waste
resources.
There
is
an
urgent
need
develop
novel
chemical
approaches
synthesize
degradable
polymers.
To
meet
with
this
demand,
it
crucial
install
degradability
into
PISA
nanoparticles.
Most
recently,
have
been
synthesized
by
introducing
degradation
mechanisms
either
shell‐forming
or
core‐forming
blocks.
This
Minireview
summarizes
development
PISA,
including
shell‐degradable,
core‐degradable,
all‐degradable
Future
will
benefit
from
expansion
techniques
new
adaptation
high‐throughput
for
both
syntheses
studies.
RSC Advances,
Год журнала:
2024,
Номер
14(4), С. 2182 - 2191
Опубликована: Янв. 1, 2024
Polyacrylamide
gel
(PAG)
is
extensively
used
as
a
matrix
for
biomolecular
analysis
and
fractionation.
However,
the
traditional
polymerization
catalyst
system
N,N,N',N'-tetramethylethylenediamine
(TEMED)/ammonium
persulphate
(APS)
of
PAG
presents
non-negligible
toxicity.
Herein,
we
utilized
green
efficient
bio-enzyme
horseradish
peroxidase
(HRP)
to
catalyze
polyacrylamide.
At
same
time,
efficacy
this
in
separating
nucleic
acids
proteins
was
confirmed
by
applying
electrophoresis.
This
study
aims
explore
higher
biosafety
polyacrylamide
catalytic
which
can
be
applied
electrophoresis
technology.
Furthermore,
order
differentiate
between
bio-enzymatic
toxic
during
polymerization,
aggregation-induced
luminescence
(AIE)
bovine
serum
albumin-stabilized
gold
nanoclusters
(BSA-Au
NCs)
monitor
reaction
system.
The
results
indicated
that
fluorescence
intensity
polymeric
containing
BSA-Au
NCs
increased
with
monomers.
Subsequently,
assessed
whether
certain
components
acid
protein
such
sodiumdodecylsulfate
(SDS)
TBE
buffer
(Tris-boric
acid,
EDTA,
pH
8.3)
would
affect
gels
catalyzed
biological
enzymes.
experimental
conditions
were
also
optimized
optimal
concentration
ternary
HRP,
H2O2
ACAC.
Our
suggested
bioenzyme-catalyzed
could
feasible
alternative
TEMED/APS-catalyzed
system,
provide
new
insights
into
methods
monitoring
