Studies on the ssDNA-Based Biosensor Regeneration and Miniaturization for Electrochemical Detection of miRNAs DOI Creative Commons

Izabela Zaras,

Marta Sokal,

Marta Jarczewska

и другие.

Journal of The Electrochemical Society, Год журнала: 2024, Номер 171(11), С. 117520 - 117520

Опубликована: Ноя. 1, 2024

One of the most significant disadvantages biosensing systems is limited possibility their regeneration, which only allows for single use detection targets. The reduction biosensor fabrication cost could thus be achieved by elaboration protocol providing highest recovery sensing layer response. A further drop production expenses yield miniaturization as it leads to consumption chemicals required receptor formation well execution measurements. To address above-mentioned challenges, we aimed find adequate method regeneration single-stranded DNA-based layers specific miRNA 141 molecule elevated concentration might refer progression cancer. studies indicated that 5 min. incubation ssDNA-modified electrode in 4 M urea provided response towards among all tested procedures. Furthermore, ssDNA immobilization on was shown. This enabled within 0.1 nM–1 μM range with high selectivity. Moreover, elaborated miniaturized transducers were distinguished sufficient stability after 24 h storage 20 mM PBS and also regenerated using urea.

Язык: Английский

Engineering metal-organic frameworks-based nanozymes for enhanced biomimetic catalytic sensing DOI
Zhong Wei Jiang, Xue Gong, Yi Wang

и другие.

TrAC Trends in Analytical Chemistry, Год журнала: 2024, Номер 178, С. 117862 - 117862

Опубликована: Июль 10, 2024

Язык: Английский

Процитировано

19
Cocatalysis of catalytic hairpin assembly and ternary heterojunction Bi2S3@MoS2@Bi2MoO6 promotes ultra-sensitive electrochemical of detection MiRNA-21 DOI
Ruizhuo Ouyang, Yuanhui Ma, Lan Jiang

и другие.

Microchimica Acta, Год журнала: 2025, Номер 192(2)

Опубликована: Янв. 31, 2025

Язык: Английский

Процитировано

0
Preparation and properties of UiO-66 based hybrid materials via surface initiated metal-free ATRP DOI Open Access
Mei-Mei Yang,

Yanhua Wang,

Hongye Li

и другие.

European Polymer Journal, Год журнала: 2023, Номер 202, С. 112612 - 112612

Опубликована: Ноя. 20, 2023

Язык: Английский

Процитировано

6
Studies on the ssDNA-Based Biosensor Regeneration and Miniaturization for Electrochemical Detection of miRNAs DOI Creative Commons

Izabela Zaras,

Marta Sokal,

Marta Jarczewska

и другие.

Journal of The Electrochemical Society, Год журнала: 2024, Номер 171(11), С. 117520 - 117520

Опубликована: Ноя. 1, 2024

One of the most significant disadvantages biosensing systems is limited possibility their regeneration, which only allows for single use detection targets. The reduction biosensor fabrication cost could thus be achieved by elaboration protocol providing highest recovery sensing layer response. A further drop production expenses yield miniaturization as it leads to consumption chemicals required receptor formation well execution measurements. To address above-mentioned challenges, we aimed find adequate method regeneration single-stranded DNA-based layers specific miRNA 141 molecule elevated concentration might refer progression cancer. studies indicated that 5 min. incubation ssDNA-modified electrode in 4 M urea provided response towards among all tested procedures. Furthermore, ssDNA immobilization on was shown. This enabled within 0.1 nM–1 μM range with high selectivity. Moreover, elaborated miniaturized transducers were distinguished sufficient stability after 24 h storage 20 mM PBS and also regenerated using urea.

Язык: Английский

Процитировано

0