Chinese Journal of Organic Chemistry, Год журнала: 2024, Номер 44(10), С. 3213 - 3213
Опубликована: Янв. 1, 2024
Язык: Английский
Chinese Journal of Organic Chemistry, Год журнала: 2024, Номер 44(10), С. 3213 - 3213
Опубликована: Янв. 1, 2024
Язык: Английский
Journal of Materials Chemistry B, Год журнала: 2024, Номер 12(27), С. 6563 - 6569
Опубликована: Янв. 1, 2024
A novel drug delivery system hitchhiking albumin as a carrier with tuneable redox-responsive release.
Язык: Английский
Процитировано
5Biomaterials Science, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
This study introduces a novel and efficient approach for constructing stimulus-responsive polycarbonates with tunable stimulus sensitivity by tailoring nanoparticle core hydrophobicity.
Язык: Английский
Процитировано
0ACS Applied Materials & Interfaces, Год журнала: 2025, Номер unknown
Опубликована: Апрель 2, 2025
Self-assembled polymeric micelles formed from amphiphilic block copolymers offer a promising strategy for enhanced drug delivery due to their biocompatibility and controlled release. However, challenges such as poor colloidal stability under diluted conditions degradation during storage circulation limit further applications. To address these issues, we developed straightforward method constructing cross-linked polycarbonate that enhance while allowing stimuli-responsive delivery. By utilizing disulfide-based cross-linking covalent conjugation of the anticancer drug, our approach maintains micelle integrity extremely high loading over extended periods well superior control triggered release compared non-cross-linked versions, demonstrating in complex biological environments improved efficacy, presenting novel platform stable polymer-drug conjugate nanocarriers, holding significant therapeutic potential targeted cancer treatment.
Язык: Английский
Процитировано
0Communications Chemistry, Год журнала: 2025, Номер 8(1)
Опубликована: Апрель 2, 2025
Язык: Английский
Процитировано
0Catalysis Letters, Год журнала: 2025, Номер 155(5)
Опубликована: Апрель 9, 2025
Язык: Английский
Процитировано
0Nano Today, Год журнала: 2024, Номер 59, С. 102526 - 102526
Опубликована: Окт. 22, 2024
Язык: Английский
Процитировано
3Chemical Research in Chinese Universities, Год журнала: 2024, Номер 40(5), С. 856 - 862
Опубликована: Июнь 18, 2024
Язык: Английский
Процитировано
1ACS Macro Letters, Год журнала: 2024, Номер 13(11), С. 1433 - 1441
Опубликована: Окт. 9, 2024
Polymeric nanocarriers have attracted significant attention in the field of anticancer drug delivery due to their unique advantages. However, designing that can maintain stability bloodstream while achieving specific release within tumor cells remains a major challenge. To address this issue, constructing reversible cross-linked polymeric are sensitive intracellular reducible glutathione (GSH) characteristic microenvironment is promising strategy. Based on this, we designed and synthesized two novel six-membered bicyclic carbonate monomers containing disulfide (DSBC) trisulfide (TSBC) bonds. Through one-step ring-opening polymerization, series reduction-sensitive polycarbonate copolymers (i.e., PEG-PDSBC PEG-PTSBC) were prepared, doxorubicin (DOX)-loaded nanoparticles fabricated using nanoprecipitation method. The
Язык: Английский
Процитировано
1Industrial & Engineering Chemistry Research, Год журнала: 2024, Номер unknown
Опубликована: Сен. 23, 2024
Язык: Английский
Процитировано
0Chinese Journal of Organic Chemistry, Год журнала: 2024, Номер 44(10), С. 3213 - 3213
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
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