Oxidative
coupling
of
2-naphthols
to
1,1'-bi-2-naphthols
in
air
at
50
°C
was
conducted
by
using
VOx
supported
on
metal
oxides
prepared
flame
spray
pyrolysis.
Among
the
tested
catalysts,
highest
yield
(91%)
achieved
VOx/t-ZrO2
(containing
7.8
wt%
as
V2O5).
The
catalytic
activity
decreased
content
increased.
At
lower
content,
catalyst
primarily
consisted
monovanadate
species
with
square
pyramidal
coordination.
As
increased,
fraction
monovanadates
decreased,
whereas
that
polyvanadates
H2
temperature-programmed
reduction
measurements
revealed
exhibited
temperatures
than
polyvanadates.
Therefore,
our
results
suggest
highly
reactive
t-ZrO2
are
active
sites
for
reaction.
European Journal of Inorganic Chemistry,
Год журнала:
2023,
Номер
26(22)
Опубликована: Июнь 28, 2023
Abstract
Metallacyclobutanes
are
intermediates
in
several
catalytic
cycles
such
as
olefin
metathesis
and
cyclopropanation.
Furthermore,
nickel
is
attracting
attention
a
versatile,
earth‐abundant
metal
developing
new
homogeneous
transformations.
In
this
context,
the
current
literature
on
nickelacyclobutanes
their
role
catalysis
reviewed.
First,
reactions
involving
(putative)
nickelacyclobutane
intermediate
discussed,
including
cyclopropanations
various
transformations
of
methylenecyclopropane.
Second,
studies
stoichiometric
reactivity
relying
direct
observation
or
even
isolation
detailed.
particular,
relationship
between
structure
highlighted.
Finally,
future
prospects
for
development
briefly
outlined.
Organic Process Research & Development,
Год журнала:
2023,
Номер
27(11), С. 1931 - 1953
Опубликована: Ноя. 1, 2023
This
Review
offers
a
comprehensive
overview
of
the
latest
advancements
in
nonprecious
metal
catalysis
(NPMC)
research,
focusing
on
period
between
July
and
October
2022.
As
part
an
ongoing
review
series,
this
account
emphasizes
diverse
synthetic
applications
Ni,
Cu,
Fe
catalysis.
The
noticeable
surge
NPMC
publications
reflects
growing
interest
among
academic
industrial
research
laboratories
exploring
harnessing
catalytic
potential
these
metals.
Chemistry - A European Journal,
Год журнала:
2024,
Номер
30(22)
Опубликована: Фев. 16, 2024
Abstract
Methylation
reactions
are
chemically
simple
but
challenging
to
perform
under
mild
and
non‐toxic
conditions.
A
photochemical
energy
transfer
strategy
was
merged
with
copper
catalysis
enable
fast
reaction
times
of
minutes
broad
applicability
N
‐heterocycles,
(hetero−)aromatic
carboxylic
acids,
drug‐like
molecules
in
high
yields
good
functional
group
tolerance.
Detailed
mechanistic
investigations,
using
kinetic
analysis,
aprotic
MS,
UV/Vis,
luminescence
quenching
experiments
revealed
a
triplet‐triplet
mechanism
between
hypervalent
iodine(III)
reagents
readily
available
photosensitizers.
Recent
global
events
have
led
to
the
cost
of
platinum
group
metals
(PGMs)
reaching
unprecedented
heights.
Many
chemical
companies
are
therefore
starting
seriously
consider
and
evaluate
if,
where,
they
can
substitute
PGMs
for
non-PGMs
in
their
catalytic
processes.
This
review
covers
recent
large-scale
applications
non-PGM
catalysts
modern
pharmaceutical
industry.
By
highlighting
these
selected
successful
examples
non-PGM-catalyzed
processes
from
literature,
we
hope
emphasize
enormous
potential
catalysis
inspire
further
development
within
this
field
enable
technology
progress
towards
manufacturing
We
also
present
some
historical
context
perceived
advantages
challenges
implementing
environment.
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(22), С. 16510 - 16521
Опубликована: Ноя. 4, 2024
Aliphatic
allylic
amines
are
present
in
a
large
number
of
complex
and
pharmaceutically
relevant
molecules.
The
direct
amination
electrophiles
serves
as
the
most
common
method
toward
preparation
these
motifs.
However,
use
feedstock
reaction
components
(allyl
alcohol
aliphatic
amine)
transformations
remains
great
challenge.
Such
challenge
primarily
stems
from
high
Lewis
basicity
steric
hindrance
amines,
addition
to
low
reactivity
alcohols.
Herein,
we
report
general
solution
challenges.
developed
protocol
allows
an
efficient
allyl
alcohols
with
sterically
bulky
presence
inexpensive
earth-abundant
molybdenum
complex.
This
simple
economic
also
enables
regioselective
branched
amination;
practicality
was
shown
efficient,
scaled-up
synthesis
several
drugs.
Iminophosphorane
P(V)
compounds
are
accessed
via
electrochemical
oxidation
of
commercially
available
P(III)
ligands,
including
mono-,
di-
and
tri-dentate
phosphines
as
well
chiral
phosphines.
The
reaction
uses
inexpensive
bis(trimethylsilyl)carbodiimide
an
efficient
safe
aminating
reagent.
DFT
calculations,
cyclic
voltammetry,
NMR
spectroscopic
studies
provide
insight
into
the
mechanism.
proposed
mechanism
based
on
data
reveals
a
special
case
sequential
paired
electrolysis,
namely
domino
electrolysis
process
in
which
intermediates
generated
at
cathode
subsequently
oxidized
anode,
followed
by
additional
convergent
process.
calculations
frontier
orbitals
iminophosphorane
compared
to
those
analogous
phosphine
oxides.
This
that
N-cyano-iminophosphoranes
have
both
higher
HOMO
lower
LUMO
than
their
oxide,
rendering
them
suitable
for
sigma-donating
pi-back-bonding.
Catalysis Science & Technology,
Год журнала:
2023,
Номер
13(23), С. 6668 - 6674
Опубликована: Янв. 1, 2023
Anti-Parkinson's
therapeutic
Azilect
was
synthesized
in
98%
ee
and
81%
yield
via
Co/
Ph
BPE-catalyzed
asymmetric
hydrogenation
as
the
key
step
for
enantioselection
a
bio-based
solvent
redox
active
Co(0)/Co(
ii
)
pathway.
Abstract
The
merger
of
two
the
most
rapidly
growing
fields
in
catalysis,
namely
gold-catalysis
and
C–H
activation/functionalization
has
resulted
major
breakthroughs,
affording
unprecedented
transformations.
This
review
covers
relevant
contributions
this
field
during
last
10
years,
restricted
to
intramolecular
functionalization
C(sp3)–H
bonds.
1
Introduction
2
Carbene/Vinylidene
Insertion
3
[1,5]-H
Shift
4
Gold-Stabilized
Vinyl
Cation
Mediated
5
Summary
Outlook
European Journal of Organic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 30, 2024
Abstract
Phase‐transfer
catalysts
(PTCs)
are
chemical
agents
that
facilitate
the
transfer
of
molecules
or
ions
between
different
reaction
phases,
thereby
accelerating
heterogeneous
processes.
Transition
metal
renowned
for
their
versatility
in
breaking
inert
bonds
and
forming
new
carbon‐carbon
bonds.
Over
past
two
decades,
integrating
with
phase‐transfer
has
emerged
as
a
highly
valuable
adaptable
strategy
modern
organic
synthesis.
This
combined
catalytic
approach
highlights
enhanced
synthetic
capabilities
demonstrates
benefits
merging
these
systems.
review
provides
an
overview
recent
advancements
asymmetric
catalysis
utilize
synergy
catalysts,
focusing
on
role
rapid
efficient
synthesis
complex
precise
stereochemistry.
