Organic Chemistry Frontiers, Год журнала: 2022, Номер 9(9), С. 2418 - 2423
Опубликована: Янв. 1, 2022
A visible-light-promoted regioselective denitrogenative cross-coupling between benzotriazinones and selenosulfonates is reported. This protocol has been further applied to a one-pot two-step synthesis of series ebselen its analogs.
Язык: Английский
European Journal of Organic Chemistry, Год журнала: 2024, Номер 27(9)
Опубликована: Фев. 8, 2024
Abstract Cycloalkanols ring‐opening transformation is one of the most valuable and wide area research. Among numerous methods that have been developed, transition‐metal‐free approaches attracted great interest from both chemists pharmacologists. This largely due to advantages being environmentally benign, cost‐effective operationally simple. Here we provide a comprehensive outline on recent advances in synthesis distally substituted ketones cyclic compounds via cycloalkanols under conditions.
Язык: Английский
Процитировано
6
Green Chemistry, Год журнала: 2020, Номер 23(1), С. 296 - 301
Опубликована: Дек. 10, 2020
The first metal-free, visible-light-induced denitrogenative phosphorylation of 1,2,3-benzotriazinones is presented.
Язык: Английский
Процитировано
36
Organic Letters, Год журнала: 2020, Номер 23(3), С. 734 - 738
Опубликована: Дек. 15, 2020
Using a facile and cost-effective method, nine bicyclic 1,2,3-triazine 2-oxides were synthesized from o-aminocyanide substrates through an unusual nitration cyclization. The reaction mechanism was studied experimentally theoretically. Moreover, 3-oxides also obtained in good yields.
Язык: Английский
Процитировано
36
Chemical Communications, Год журнала: 2021, Номер 57(12), С. 1506 - 1509
Опубликована: Янв. 1, 2021
Silver-catalyzed direct C–H functionalization of cyclic aldimines with cyclopropanols and cyclobutanols via a radical-mediated C–C bond cleavage strategy has been realized, generating the desired products in decent yields wide substrate scope.
Язык: Английский
Процитировано
32
Chemical Communications, Год журнала: 2021, Номер 57(48), С. 5929 - 5932
Опубликована: Янв. 1, 2021
Merging both C–H and C–C activation in a tandem process is highly appealing but marked challenge.
Язык: Английский
Процитировано
30
Organic Letters, Год журнала: 2022, Номер 24(31), С. 5741 - 5745
Опубликована: Авг. 2, 2022
A nickel-catalyzed denitrogenative cross-electrophile-coupling of benzotriazinones with unactivated alkyl halides (X = Cl, Br, I) in the presence manganese powder as a reductant has been developed. The reaction furnishes ortho-alkylated secondary benzamides modest to good yields under mild conditions. scope is demonstrated 25 examples, showing tolerance steric hindrance and common functional groups, thus providing an efficient protocol benzamide derivatives without use preprepared organometallic reagents.
Язык: Английский
Процитировано
21
The Journal of Organic Chemistry, Год журнала: 2022, Номер 87(13), С. 8752 - 8756
Опубликована: Июнь 14, 2022
An efficient trifluoroacetic acid-mediated denitrogenative hydroxylation of 1,2,3-benzotriazin-4(3H)-ones is described. This metal-free approach compatible with a wide range 1,2,3-benzotriazin-4(3H)-ones, affording ortho-hydroxylated benzamides in good to high yields short reaction time. The believed proceed via benzene diazonium intermediate. synthetic utility the was successfully demonstrated by preparation an antimicrobial drug, Riparin C, and benzoxazine-2,4(3H)-diones yields.
Язык: Английский
Процитировано
20
Organic Letters, Год журнала: 2022, Номер 24(49), С. 9012 - 9016
Опубликована: Дек. 5, 2022
An expedient synthesis of benzo[c][1,2]dithiol-3-ones via metal-free denitrogenative transannulation benzotriazinones is developed, which represents the first example acid-mediated heteroannulation benzotriazinones. This newly discovered reactivity enables streamline diverse in decent yields by using sodium sulfide as sulfur source under simple reaction conditions.
Язык: Английский
Процитировано
20
ChemistrySelect, Год журнала: 2023, Номер 8(32)
Опубликована: Авг. 23, 2023
Abstract Cyclopropanols, due to their particular chemistry, can participate in various synthetic reactions with retention or cleavage of the strained three‐membered ring. Direct cross‐coupling ring‐opening reaction such molecules access organic compounds, as ketones has great importance medicinal chemistry and material sciences. Hence, coupling reaction/cyclization cyclopropanols for constructing new valuable presence a transition metal catalyst under metal‐free conditions is described this context. The features are discussed, mechanisms challenging highlighted.
Язык: Английский
Процитировано
12
Green Chemistry, Год журнала: 2024, Номер 26(3), С. 1375 - 1380
Опубликована: Янв. 1, 2024
A visible-light-mediated tandem ring opening/1,6-conjugate addition of cyclobutanols with p -quinone methides was developed. This protocol allowed the formation δ,δ-diaryl ketones in presence a readily available organic photocatalyst.
Язык: Английский
Процитировано
5