European Journal of Organic Chemistry,
Год журнала:
2023,
Номер
unknown
Опубликована: Авг. 31, 2023
Abstract
Achieving
high
molecular
complexity
can
be
not
trivial,
but
the
exploitation
of
domino
reactions
provides
an
atom‐
and
step‐economical
method
to
reach
this
target.
Over
past
decades,
a
lot
efforts
have
been
put
on
development
photocatalytic
cascades
employing
both
metal‐based
purely
organic
catalysts.
Despite
effectiveness
these
protocols,
catalyst‐
additive‐free
light‐induced
are
gaining
momentum
thank
their
efficiency,
operational
simplicity
sustainability.
The
increasing
number
papers
published
field
in
last
years
is
proof
appeal
transformations.
In
Review,
we
discuss
multicomponent
mediated
by
light
with
focus
photocatalyst‐
processes.
most
recent
advances
synthesis
complex
nitrogen‐,
oxygen‐,
sulphur‐
selenium‐heterocycles
together
analysed
emphasis
experimental
mechanistic
studies.
Organic Letters,
Год журнала:
2021,
Номер
23(8), С. 2976 - 2980
Опубликована: Март 29, 2021
A
general
and
metal-free
visible-light-induced
decarboxylative
arylation
procedure
at
room
temperature
was
described
for
the
construction
of
acylated
heterocyclic
derivatives,
such
as
benzimidazo/indolo[2,1-a]isoquinolin-6(5H)-ones,
aroylazaspiro[4.5]trienones,
thioflavones,
so
on.
This
practical
conducted
by
using
2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile
(4CzIPN)
a
photocatalyst
under
mild
conditions,
which
avoided
use
an
additional
base,
traditional
heating,
metal
reagents.
Organic Letters,
Год журнала:
2023,
Номер
25(38), С. 7014 - 7019
Опубликована: Сен. 18, 2023
Organoelectrophotocatalytic
generation
of
acyl
radicals
from
formamides
and
aldehydes
to
synthesize
acylated
3-CF3-2-oxindoles
has
been
developed.
This
protocol
features
a
monocatalytic
system
using
9,10-phenanthrenequinone
(PQ)
both
as
catalyst
hydrogen
atom
transfer
(HAT)
reagent,
which
avoids
the
use
an
external
HAT
metal
oxidant.
A
variety
have
obtained
in
satisfactory
yields
CF3-substituted
N-arylacrylamides
via
tandem
radical
cyclization.
The Journal of Organic Chemistry,
Год журнала:
2020,
Номер
86(1), С. 917 - 928
Опубликована: Дек. 7, 2020
We
developed
a
green
method
for
the
synthesis
of
spiro[4.5]trienones
through
an
electrochemical
oxidative
halocyclization
with
N-aryl
alkynamides.
This
reaction
was
conducted
under
metal-catalyst-
and
exogenous-oxidant-free
conditions
at
room
temperature.
Using
readily
available
LiCl,
LiBr,
LiI
as
halogen
source,
variety
dearomative
halo-spirocyclization
products
were
obtained
in
good
to
excellent
yields
broad
scope
functional
group
tolerance.
Organic Chemistry Frontiers,
Год журнала:
2020,
Номер
8(4), С. 760 - 766
Опубликована: Дек. 21, 2020
Photocatalytic
strategies
for
the
preparation
of
3-functionalized
azaspiro[4.5]trienones
via
a
radical-initiated
cascade
annulation
reaction
was
developed.
The Journal of Organic Chemistry,
Год журнала:
2021,
Номер
86(23), С. 17071 - 17081
Опубликована: Ноя. 22, 2021
Electrooxidative-induced
synthesis
of
structurally
diverse
seleno-dibenzocyclohepten-5-ones
and
seleno-spiro[5.5]trienones
by
selenylative
carbannulation
biaryl
ynones
with
diaryl
diselenide
has
been
developed.
The
switchable
reactivity,
intramolecular
ortho-annulation
or
dearomative
ipso-annulation,
is
directed
the
substituent
present
on
ortho-aryl
group
aryl-ynone.
prominent
features
this
method
include
metal-free,
external
chemical
oxidant-free
conditions,
readily
accessible
substrates.
Chemical Communications,
Год журнала:
2020,
Номер
56(82), С. 12367 - 12370
Опубликована: Янв. 1, 2020
An
efficient
K2S2O8-mediated
oxidative
cascade
spirocyclization
of
N-arylpropiolamides
with
aryl
glyoxylic
acids
was
demonstrated
for
constructing
azaspiro[4,5]-trienones
and
complex
azaspiro-fused
architectures.
Organic Letters,
Год журнала:
2020,
Номер
22(21), С. 8407 - 8412
Опубликована: Окт. 13, 2020
A
visible-light-mediated
protocol
for
the
hydroacylation
of
azobenzenes
with
α-keto
acids
has
been
developed.
In
absence
any
catalyst
or
additive,
decarboxylative
proceeded
smoothly
under
visible-light
irradiation
at
room
temperature.
wide
range
and
were
well-tolerated
afforded
products
in
high
to
excellent
yields.
Preliminary
investigations
indicated
that
photoactive
absorb
visible
light
enable
transformation.
Advanced Synthesis & Catalysis,
Год журнала:
2021,
Номер
363(18), С. 4440 - 4446
Опубликована: Июль 23, 2021
Abstract
A
nitrogen‐centered
radical
strategy
for
the
preparation
of
3‐acylated
spiro[4,5]trienones
via
visible‐light‐mediated
acylation/
ipso
‐cyclization
alkynes
with
acyl
oxime
esters
is
reported.
The
alkyl‐
and
aryl‐substituted
radicals,
which
generate
from
cleavage
carbon‐carbon
σ
‐bonds
in
pathway,
attack
triple
bonds
propiolamides
then
undergo
‐cyclization.
This
method
provides
a
way
construction
3‐acyl‐substituted
spiro[4,5]trienones,
can
introduce
aryl‐
or
alkyl‐substituted
into
spiro[4,5]trienone
skeletons.
magnified
image
