The Journal of Organic Chemistry,
Год журнала:
2020,
Номер
85(23), С. 15752 - 15759
Опубликована: Ноя. 13, 2020
Rhodium-catalyzed
directed
C-H
functionalization
of
2-arylindazoles
with
N-sulfonylformaldimines
has
been
developed
to
provide
a
variety
N-benzylarylsulfonamide
derivatives
good
excellent
yields.
Different
activated
aldehydes
like
ethyl
glyoxalate
and
2,2,2-trifluoroacetaldehyde
also
efficiently
underwent
nucleophilic
addition
2-arylindazoles.
These
selective
transformations
occur
through
the
control
C3
nucleophilicity
indazole
moiety.
Mechanistic
studies
suggest
that
activation
step
may
be
rate-limiting
step.
Chemical Reviews,
Год журнала:
2021,
Номер
122(2), С. 1925 - 2016
Опубликована: Сен. 29, 2021
The
fields
of
C–H
functionalization
and
photoredox
catalysis
have
garnered
enormous
interest
utility
in
the
past
several
decades.
Many
different
scientific
disciplines
relied
on
strategies
including
natural
product
synthesis,
drug
discovery,
radiolabeling,
bioconjugation,
materials,
fine
chemical
synthesis.
In
this
Review,
we
highlight
use
reactions.
We
separate
review
into
inorganic/organometallic
catalysts
organic-based
catalytic
systems.
Further
subdivision
by
reaction
class─either
sp2
or
sp3
functionalization─lends
perspective
tactical
for
these
methods
synthetic
applications.
Advanced Synthesis & Catalysis,
Год журнала:
2021,
Номер
363(22), С. 5047 - 5071
Опубликована: Окт. 1, 2021
Abstract
Electrochemical
synthesis
offers
a
mild,
simple,
and
efficient
tool
for
the
preparation
of
interesting
useful
molecules,
thus
eluding
severe
chemical
oxidizing
reducing
agents
used
in
conventional
synthetic
methods.
In
particular,
electrochemical
C−H
activation
is
expected
to
play
an
important
role
direct
functionalization
heterocyclic
compounds.
Over
past
few
decades,
research
interest
imidazopyridine
indazole
has
increased
significantly
due
their
multipurpose
uses
medicinal
industrial
chemistry.
Therefore,
structural
modification
these
heterocycles
using
electro‐oxidation
become
one
topics
among
organic
chemistry
recent
time.
This
review
provides
comprehensive
discussion
indazoles
imidazopyridines
published
so
far.
A
summary
current
challenges
future
direction
development
green
methods
also
presented.
magnified
image
Organic & Biomolecular Chemistry,
Год журнала:
2021,
Номер
19(11), С. 2399 - 2415
Опубликована: Янв. 1, 2021
Visible-light-driven
functionalization
of
various
organic
systems
has
proved
to
be
extremely
successful
and
reached
an
impressive
level
sophistication
as
well
efficiency
in
the
last
two
decades.
At
same
time,
organosilicon
compounds
are
significant
due
their
promising
applications
therapeutic
agents,
drug
delivery,
building
blocks
so
on.
More
interestingly,
they
cheap,
operationally
simple,
highly
stable,
less
toxic
easy
handle.
In
this
scenario,
environment-friendly
synthetic
approach
for
silylation,
such
visible-light-induced
is
high
demand
at
present
molecule
construction
having
C-Si
bond.
This
perspective
summarizes
recent
findings
developments
emerging
area
photocatalytic
silylation
with
literature
coverage
mainly
extending
from
2014
February
2021.
Chemical Communications,
Год журнала:
2022,
Номер
58(28), С. 4435 - 4455
Опубликована: Янв. 1, 2022
Indazole
and
pyrazole
are
renowned
as
a
prodigious
class
of
heterocycles
having
versatile
uses
in
medicinal
well
industrial
chemistry.
Considering
sustainable
approaches,
recently,
photocatalysis
has
become
an
indispensable
tool
organic
chemistry
due
to
its
application
for
the
activation
small
molecules
use
clean
energy
source.
In
this
review,
we
have
highlighted
metal-based
photocatalysts,
photoredox
catalysts,
transfer
photocatalysts
electron-donor-acceptor
complexes
functionalization
indazole
pyrazole.
This
perspective
is
arranged
based
on
types
reactions
A
detailed
discussion
regarding
reaction
mechanism
each
given
provide
comprehensive
guide
reader.
Finally,
summary
existing
challenges
future
outlook
towards
development
efficient
photocatalytic
methods
these
also
presented.
Green Chemistry,
Год журнала:
2022,
Номер
24(8), С. 3056 - 3080
Опубликована: Янв. 1, 2022
This
critical
review
chronologically
summarizes
the
metal-free
coupling
methodologies
of
C(sp
3
)–H
sources
with
heteroarenes
induced
by
visible
light.
The
articles
which
are
published
up
to
January
2022
on
this
topic
enclosed
here.
Organic Chemistry Frontiers,
Год журнала:
2022,
Номер
9(5), С. 1445 - 1450
Опубликована: Янв. 1, 2022
A
visible-light-driven
rhodamine
B-catalyzed
transition-metal-free
3-ethoxycarbonylmethylation
of
2-aryl-2
H
-indazoles
and
imidazo[1,2-
a
]pyridines
(40
examples)
using
commercially
available
α-bromoesters
was
realized
in
water.
Green Chemistry,
Год журнала:
2023,
Номер
25(21), С. 8459 - 8493
Опубликована: Янв. 1, 2023
This
review
comprehensively
summarizes
visible
light-induced
difunctionalization
strategies
for
alkene
and
alkyne
systems
in
metal-free
conditions
with
literature
coverage
up
to
July
2023.
Organic & Biomolecular Chemistry,
Год журнала:
2023,
Номер
21(8), С. 1591 - 1628
Опубликована: Янв. 1, 2023
Photoredox
catalysis
has
demonstrated
rapid
evolution
in
the
field
of
synthetic
organic
chemistry.
On
other
hand,
splendour
cascade
reactions
providing
complex
molecular
architectures
renders
them
a
cutting-edge
research
area.
Therefore,
merging
photocatalysis
with
synthesis
brings
out
paradigm
immense
potential.
The
development
photocascade
for
target
molecule
particular
skeleton
and
stereochemical
framework
presents
certain
challenges
but
provides
robust
environmentally
benign
alternative.
This
comprehensive
review
assembles
all
accomplishments
highlights
visible-light-induced
literature
coverage
up
to
October
2022.
Advanced Synthesis & Catalysis,
Год журнала:
2024,
Номер
366(10), С. 2186 - 2208
Опубликована: Апрель 4, 2024
Abstract
This
review
presents
an
outline
of
current
advancements
in
the
photochemical
and
electrochemical
synthesis
oxazoles
isoxazoles.
Oxazole
isoxazole
are
important
building
blocks
for
a
variety
medicinally
useful
compounds.
Therefore,
these
heterocycles
via
sustainable
technologies
is
worth
demanding.
Photochemical
two
among
few
technologies.
covers
brief
discussion
on
reaction
parameters
like
catalysts,
substrates
scope,
temperature,
solvents,
electrodes,
electrolytes
(in
case
process),
light
source
process)
individual
reaction.
Detailed
mechanistic
insight
each
also
presented.
Finally,
summary,
future
direction
toward
development
effective
methods
isoxazoles
