Organic Letters,
Год журнала:
2022,
Номер
24(36), С. 6647 - 6652
Опубликована: Сен. 2, 2022
A
visible-light-promoted
three
component
reaction
of
diazo
compounds,
nitriles,
and
carboxylic
acids
is
reported.
The
utilizes
acceptor-only
compounds
as
carbene
precursors
nitriles
carbene-trapping
reagents
to
form
the
key
nitrile
ylides.
Under
optimal
conditions,
a
wide
range
imide
products
were
obtained
in
good
excellent
yields.
gram-scale
synthesis
synthetic
application
isoquinoline-1,3(2H,4H)-dione
derivatives
further
proved
value
this
method.
Chemical Reviews,
Год журнала:
2024,
Номер
124(11), С. 7214 - 7261
Опубликована: Май 16, 2024
In
recent
years,
visible
light-induced
reactions
of
diazo
compounds
have
attracted
increasing
attention
in
organic
synthesis,
leading
to
improvement
existing
reactions,
as
well
the
discovery
unprecedented
transformations.
Thus,
photochemical
or
photocatalytic
generation
both
carbenes
and
radicals
provide
milder
tools
toward
these
key
intermediates
for
many
valuable
However,
vast
majority
transformations
represent
new
reactivity
modes
compounds,
which
are
achieved
by
decomposition
photoredox
catalysis.
particular,
use
a
redox-active
photocatalysts
opens
avenue
plethora
radical
reactions.
The
application
methods
led
inaccessible
classical
associated
with
metal
carbenes.
most
cases,
act
sources
but
can
also
serve
acceptors.
Importantly,
described
processes
operate
under
mild,
practical
conditions.
This
Review
describes
this
subfield
compound
chemistry,
particularly
focusing
on
advancements.
Chemical Communications,
Год журнала:
2023,
Номер
59(48), С. 7346 - 7360
Опубликована: Янв. 1, 2023
This
article
discusses
the
photochemistry
of
several
diazo
compounds
undergoing
visible
light-mediated
photolysis
to
generate
free
carbenes
(or
other
highly
reactive
intermediates),
which
can
be
sequentially
trapped
by
different
reacting
partners.
Chemical Communications,
Год журнала:
2024,
Номер
60(16), С. 2125 - 2136
Опубликована: Янв. 1, 2024
In
this
feature
article,
we
focus
on
the
photochemical
strategy
for
construction
of
heterocyclic
skeletons,
specifically
highlighting
methods
that
employ
visible
light-promoted
carbene
transfer
reactions.
Chinese Journal of Organic Chemistry,
Год журнала:
2021,
Номер
41(12), С. 4565 - 4565
Опубликована: Янв. 1, 2021
Carbene
is
one
of
the
most
important
synthetic
intermediates
in
organic
synthesis.In
past
few
decades,
transition-metal
catalyzed
carbene
transfer
reactions
have
made
remarkable
development.Recently,
visible
light-promoted
transformation
diazo
compounds
through
formation
free
as
key
intermediate
begun
to
rise.The
reaction
only
need
light
sole
energy
source
which
meets
concept
green
chemistry.Since
pioneering
works
developed
by
groups
Diaves
and
Zhou,
photo-promoted
has
attracted
more
attentions.On
basis
previous
work,
latest
progress
this
field
further
improved,
mainly
focuses
on
recent
new
under
irradiation
contributions
reported
from
Chinese
research
group.The
future
development
direction,
well
challenges
prospected.
Organic Letters,
Год журнала:
2021,
Номер
23(17), С. 6951 - 6955
Опубликована: Авг. 12, 2021
A
green
and
sustainable
oxime
ether
formation
method
via
the
visible-light-promoted
O–H
functionalization
of
oximes
with
diazo
esters
is
described.
The
reaction
occurs
under
very
mild
conditions
(catalyst-
additive-free)
a
high
yield
functional
group
tolerance.
When
was
performed
cyclic
as
solvent
(e.g.,
THF,
1,4-dioxane,
tetrahydropyran,
ect.),
an
interesting
photochemical
three-component
product
obtained
in
good
yields.
Chemistry - An Asian Journal,
Год журнала:
2021,
Номер
17(1)
Опубликована: Ноя. 26, 2021
With
eco-friendly
and
sustainable
CO2
-derived
dimethyl
carbonate
as
the
sole
solvent,
visible-light-induced
cascade
radical
reactions
have
been
established
a
green
efficient
tool
for
constructing
various
CHF2
/CClF2
/CBrF2
-substituted
ring-fused
quinazolinones.
Organic Letters,
Год журнала:
2021,
Номер
24(1), С. 299 - 303
Опубликована: Дек. 16, 2021
A
sustainable
and
cost-effective
manner
for
the
photocatalytic
annulation
reaction
of
N-sulfonyl
ketimines
with
N-arylglycines
to
synthesize
imidazolidine-fused
sulfamidates
(31
examples)
by
employing
CsPbBr3
as
a
heterogeneous
photocatalyst
has
been
developed.
The
catalyst
can
be
simply
recovered
from
mixture
reused
at
least
five
times
without
an
obvious
reduction
in
its
reactivity,
exhibiting
high
economic
feature.
ACS Catalysis,
Год журнала:
2022,
Номер
12(9), С. 5510 - 5516
Опубликована: Апрель 25, 2022
We
developed
an
efficient
visible-light-mediated
formal
carbene
insertion
reaction
of
1,3-diketones
with
diazoesters
for
the
construction
enantioenriched
1,4-dicarbonyl
compounds
a
quaternary
carbon
center.
Combining
visible
light
and
Brønsted
acid
catalyst,
chiral
were
achieved
in
good
yields
high
enantioselectivities
by
photochemical
transfer
protocol.
Organic Letters,
Год журнала:
2022,
Номер
24(32), С. 6018 - 6023
Опубликована: Авг. 10, 2022
We
disclosed
herein
a
straightforward
photochemical
method
for
the
construction
of
phenanthridines
containing
synthetically
useful
succinate
unit.
The
reaction
occurred
under
visible-light
irradiation
with
cheap
eosin
Y
Na
as
photoredox
catalyst
and
diazo
compound
precursor.
Under
optimal
conditions,
wide
range
were
obtained
in
moderate
to
good
yields.
Note
that
units
final
heterocycles
could
be
easily
transformed
into
many
valuable
structures,
such
γ-butyrolactone,
dihydrofuran-2(3H)-one,
tetrahydrofuran.
Mechanistic
experiments
performed
support
proposed
mechanism.
European Journal of Organic Chemistry,
Год журнала:
2022,
Номер
2022(44)
Опубликована: Окт. 21, 2022
Abstract
Cyclopropanes
are
one
of
the
most
important
strained
rings
existing
in
various
pharmaceutical
products
and
secondary
metabolites.
They
also
widely
used
total
synthesis
natural
products,
medicinal
chemistry,
materials
science.
In
past
years,
photochemical
cyclopropanation
has
been
gradually
developed
as
a
robust
attractive
synthetic
method
to
prepare
diverse
cyclopropane
backbones.
this
review,
we
summarize
recent
advances
visible
light‐mediated
synthesis,
especially
using
carbene
transfer
strategy
photocatalytic
radical
reactions.
