The Journal of Organic Chemistry,
Год журнала:
2022,
Номер
87(19), С. 12921 - 12931
Опубликована: Сен. 21, 2022
A
simple
visible-light-initiated
strategy
has
been
established
for
the
construction
of
organophosphorus
compounds
via
aerobic
multicomponent
reaction
α-diazoesters,
cyclic
ethers,
and
P(O)H
under
air.
number
phosphonates
phosphinates
could
be
efficiently
isolated
in
moderate
to
good
yields
without
use
photosensitizers
metal
reagents.
This
advantages
mild
condition,
operation,
eco-friendly
energy,
functional-group
tolerance,
gram-scale
synthesis.
ACS Catalysis,
Год журнала:
2022,
Номер
12(20), С. 12530 - 12542
Опубликована: Сен. 30, 2022
In
the
presence
of
1,1,1,3,3,3-hexafluoroisopropanol
(HFIP),
nucleophilic
and
reactive
reagents
are
prevented
from
interacting
with
a
rhodium
carbene,
allowing
asymmetric
cyclopropanation
to
occur
high
yield
stereoselectivity
on
variety
compounds.
A
high-throughput
screen
was
conducted
complementary
catalytic
system
in
90
different
poisonous
nucleophiles
varying
amounts
HFIP
(10
equiv,
used
as
reaction
solvent).
The
scope
both
aryl/heteroaryl
diazoacetate
olefin
expanded,
study
culminated
enantioselective
functionalization
complex
molecules
including
API
natural
products.
The Journal of Organic Chemistry,
Год журнала:
2021,
Номер
86(23), С. 17528 - 17532
Опубликована: Ноя. 18, 2021
Two
visible-light-mediated
O–H
insertion
protocols
involving
oximes
and
aryldiazoacetates
leading
to
different
products
depending
on
the
solvent
employed
are
reported.
In
DCM,
direct
takes
place.
THF,
there
is
additional
incorporation
of
ring-opened
form
this
into
structure
product.
These
metal-free
mild
tolerant
air
moisture.
The
preparation
an
acaricide
has
been
developed
as
example
synthetic
application.
The Journal of Organic Chemistry,
Год журнала:
2022,
Номер
87(19), С. 12921 - 12931
Опубликована: Сен. 21, 2022
A
simple
visible-light-initiated
strategy
has
been
established
for
the
construction
of
organophosphorus
compounds
via
aerobic
multicomponent
reaction
α-diazoesters,
cyclic
ethers,
and
P(O)H
under
air.
number
phosphonates
phosphinates
could
be
efficiently
isolated
in
moderate
to
good
yields
without
use
photosensitizers
metal
reagents.
This
advantages
mild
condition,
operation,
eco-friendly
energy,
functional-group
tolerance,
gram-scale
synthesis.
