Visible-Light-Mediated Strategies for the Preparation of Oxime Ethers Derived from O–H Insertions of Oximes into Aryldiazoacetates DOI
Mateus L. Stivanin, M.T. Duarte, Luiz Paulo Melchior de Oliveira Leão

et al.

The Journal of Organic Chemistry, Journal Year: 2021, Volume and Issue: 86(23), P. 17528 - 17532

Published: Nov. 18, 2021

Two visible-light-mediated O–H insertion protocols involving oximes and aryldiazoacetates leading to different products depending on the solvent employed are reported. In DCM, direct takes place. THF, there is additional incorporation of ring-opened form this into structure product. These metal-free mild tolerant air moisture. The preparation an acaricide has been developed as example synthetic application.

Language: Английский

Lewis acid-catalyzed diazo insertion into electron-deficient C–H bonds DOI

Jalaj Kumar Pathak,

Namrata Rastogi

Journal of Chemical Sciences, Journal Year: 2025, Volume and Issue: 137(2)

Published: April 29, 2025

Language: Английский

Citations

0
C(sp3)—H Bond Oximinylation DOI

Antuo Xu,

Junyi Li, Qiang Liu

et al.

Acta Chimica Sinica, Journal Year: 2025, Volume and Issue: 83(4), P. 390 - 390

Published: Jan. 1, 2025

Language: Английский

Citations

0
Hexafluoroisopropanol for the Selective Deactivation of Poisonous Nucleophiles Enabling Catalytic Asymmetric Cyclopropanation of Complex Molecules DOI

Jack C. Sharland,

David I. Dunstan,

Dyuti Majumdar

et al.

ACS Catalysis, Journal Year: 2022, Volume and Issue: 12(20), P. 12530 - 12542

Published: Sept. 30, 2022

In the presence of 1,1,1,3,3,3-hexafluoroisopropanol (HFIP), nucleophilic and reactive reagents are prevented from interacting with a rhodium carbene, allowing asymmetric cyclopropanation to occur high yield stereoselectivity on variety compounds. A high-throughput screen was conducted complementary catalytic system in 90 different poisonous nucleophiles varying amounts HFIP (10 equiv, used as reaction solvent). The scope both aryl/heteroaryl diazoacetate olefin expanded, study culminated enantioselective functionalization complex molecules including API natural products.

Language: Английский

Citations

18
Copper-catalyzed 2,3-dihydro-1,2,4-triazoles synthesis through [3+2]-cycloaddition of nitrile ylides with azodicarboxylates DOI Creative Commons
Bao‐Gui Cai, Qian Li, Jun Xuan

et al.

Green Synthesis and Catalysis, Journal Year: 2024, Volume and Issue: 5(3), P. 191 - 194

Published: Aug. 1, 2024

A copper-catalyzed three-component reaction of diazo compounds, nitriles, and azodicarboxylates to construct 2,3-dihydro-1,2,4-triazoles is reported. Key the success utilization trap in-situ formed nitrile ylides from compounds by [3 ​+ ​2]-cycloaddition. Both acceptor-only donor-acceptor are all tolerated strategy. The synthetic value this protocol illustrated gram-scale synthesis valuable transformation obtained 2,3-dihydro-1,2,4-triazoles.

Language: Английский

Citations

3
Visible-Light-Mediated Strategies for the Preparation of Oxime Ethers Derived from O–H Insertions of Oximes into Aryldiazoacetates DOI
Mateus L. Stivanin, M.T. Duarte, Luiz Paulo Melchior de Oliveira Leão

et al.

The Journal of Organic Chemistry, Journal Year: 2021, Volume and Issue: 86(23), P. 17528 - 17532

Published: Nov. 18, 2021

Two visible-light-mediated O–H insertion protocols involving oximes and aryldiazoacetates leading to different products depending on the solvent employed are reported. In DCM, direct takes place. THF, there is additional incorporation of ring-opened form this into structure product. These metal-free mild tolerant air moisture. The preparation an acaricide has been developed as example synthetic application.

Language: Английский

Citations

22