Advanced Synthesis & Catalysis,
Год журнала:
2023,
Номер
365(8), С. 1179 - 1184
Опубликована: Апрель 1, 2023
Abstract
Under
heating
conditions,
an
iron(II)‐catalyzed
cascade
cyanoalkylsulfonylation/cyclization
reaction
is
developed
to
produce
cyanoalkylsulfonylated
pyrrolidones
bearing
with
a
free
CN
moiety.
This
alkyl
radical
disconnection
and
annulation
protocol
enjoys
chemo‐
regioselectivity
the
tolerance
toward
range
of
functional
groups.
The
reactive
cyanoalkyl
radical,
which
was
originated
from
ring‐opening
cyclic
imine
found
be
capable
capturing
in‐situ
generated
“SO
2
”
species
DABSO,
thus
leading
production
sulfonyl
subsequent
alkene
sequences.
magnified
image
Organic Letters,
Год журнала:
2021,
Номер
23(21), С. 8455 - 8459
Опубликована: Окт. 15, 2021
A
radical-mediated
three-component
1,4-sulfonylarylation
of
1,3-enynes
with
aryl
iodides
and
sulfinate
salts
using
cooperative
photoredox/nickel
catalysis
is
described.
This
protocol
enables
the
synthesis
tetrasubstituted
sulfonyl-containing
allenes
under
redox-neutral
conditions
provides
a
versatile
1,3-enyne
1,4-difunctionalization
platform
for
diverse
range
high
chemo-
regioselectivities,
excellent
functional
group
tolerance,
broad
substrate
scope.
Organic Chemistry Frontiers,
Год журнала:
2022,
Номер
9(14), С. 3781 - 3785
Опубликована: Янв. 1, 2022
A
photoredox-catalyzed
reaction
of
thianthrenium
salts,
hydrazines
and
DABCO·(SO
2
)
is
accomplished,
providing
diverse
arenesulfonohydrazides
in
moderate
to
good
yields
under
mild
conditions.
Organic Chemistry Frontiers,
Год журнала:
2022,
Номер
9(7), С. 1937 - 1942
Опубликована: Янв. 1, 2022
An
iron-catalyzed
dearomative
spirocyclization
of
biaryl
ynones
with
sodium
metabisulfite
and
cycloketone
oxime
esters
is
developed
for
the
construction
sulfonated
spiro[5,5]trienones.
European Journal of Organic Chemistry,
Год журнала:
2023,
Номер
26(25)
Опубликована: Апрель 25, 2023
Abstract
Compounds
containing
sulfonyl‐derived
functional
groups
have
received
intensive
attention
owing
to
their
widespread
applications
in
life
science,
pharmaceuticals
and
materials
science.
To
access
this
type
of
compounds,
the
multi‐component
sulfonylation
reactions
relying
on
sulfur
dioxide
(SO
2
)
insertion
strategy
emerged
as
novel
attractive
approaches
past
decade.
The
utilization
SO
surrogates
for
multicomponent
(MCRs)
improved
reaction
flexibility
step
economy.
Moreover,
some
advances
been
achieved
challenging
but
practical
asymmetric
MCRs
construction
high
value‐added
chiral
sulfones.
This
review
aims
summarize
progress
made
involving
from
2019
2022,
point
out
potentials
challenges
field.
Molecules,
Год журнала:
2023,
Номер
28(7), С. 3027 - 3027
Опубликована: Март 28, 2023
Radical
transformations
are
powerful
in
organic
synthesis
for
the
construction
of
molecular
scaffolds
and
introduction
functional
groups.
In
radical
difunctionalization
reactions,
radicals
first
functionalized
intermediates
can
be
relocated
through
resonance,
hydrogen
atom
or
group
transfer,
ring
opening.
The
resulting
undertake
following
paths
second
functionalization:
(1)
couple
with
other
groups,
(2)
oxidize
to
cations
then
react
nucleophiles,
(3)
reduce
anions
electrophiles,
(4)
metal-complexes.
rearrangements
provide
opportunity
1,3-,
1,4-,
1,5-,
1,6-,
1,7-difunctionalization
products.
Multiple
ways
initiate
reaction
coupling
intermediate
make
reactions
good
at
remote
positions.
These
offer
advantages
synthetic
efficiency,
operation
simplicity,
product
diversity.
Organic Chemistry Frontiers,
Год журнала:
2023,
Номер
10(9), С. 2251 - 2256
Опубликована: Янв. 1, 2023
We
report
an
enantioselective
sulfonylation
of
α,β-unsaturated
carbonyl
compounds
with
4-alkyl
substituted
Hantzsch
esters
and
DABCO·(SO
2
)
by
interfacing
photoredox
hydrogen
bonding
catalysis.
Organic Chemistry Frontiers,
Год журнала:
2023,
Номер
10(11), С. 2773 - 2781
Опубликована: Янв. 1, 2023
A
regio-
and
enantioselective
radical
three-component
coupling
of
1,3-enynes,
oxime
esters,
carboxylic
acids
through
photoinduced
copper
catalysis
is
reported.
Green Chemistry,
Год журнала:
2023,
Номер
25(10), С. 3857 - 3863
Опубликована: Янв. 1, 2023
A
general
and
environmentally
friendly
organic
photo-induced
strategy
was
developed
for
the
synthesis
of
diverse
alkyl-substituted
β-amino
sulfone
derivatives,
including
primary,
secondary,
tertiary
products.
Organic Chemistry Frontiers,
Год журнала:
2023,
Номер
10(19), С. 4972 - 5027
Опубликована: Янв. 1, 2023
This
review
comprehensively
summarizes
the
dichalcogenative
functionalization
of
unsaturated
compounds
over
past
decade.
The
scopes,
limitations
and
detailed
reaction
mechanisms
are
also
discussed.
ACS Catalysis,
Год журнала:
2023,
Номер
13(3), С. 2142 - 2148
Опубликована: Янв. 25, 2023
Allenol
has
been
identified
as
a
versatile
building
block
for
organic
synthesis,
and
numerous
efforts
have
made
to
synthesize
apply
allenol.
However,
limited
obtain
trifluoromethyl-substituted
Here,
by
using
readily
available
1,3-enyne
the
starting
material,
copper-catalyzed
trifluoromethylbenzoxylation
process
was
developed
efficient
synthesis
of
allenols
Togni-II
reagent
reaction
partner.
Triple
roles
reagent,
including
source
trifluoromethyl
group,
hydroxyl
oxidant,
were
elucidated
in
this
transformation.
Moreover,
late-stage
diversification
performed,
which
revealed
application
potential
preparation
various
compounds.
