Visible-Light-Promoted bis(Difluoromethylation)/Cyclization of 2-Vinyloxy Arylalkynes to Prepare Benzofuran Derivatives DOI
Huan Wang, Yao Huang,

Qiaoyan Wu

и другие.

The Journal of Organic Chemistry, Год журнала: 2022, Номер 87(19), С. 13288 - 13299

Опубликована: Сен. 27, 2022

A visible-light-promoted difluoromethylation/cyclization of 2-vinyloxy arylalkynes was developed, providing a variety bis(difluoromethyl)-substituted benzofurans in moderate to good yields. plausible mechanism involving difluoromethyl radical cascade cyclization and solvent-promoted ionic addition proposed. This protocol has the advantages having mild reaction conditions, simple operation, functional group tolerance.

Язык: Английский

Photocatalytic cyclization of 3-(2-isocyanophenyl)quinazolin-4(3H)-ones for the construction of quinoxalino[2,1-b]quinazolinones DOI

Xian Wu,

Ling-Li Liu,

Chengli Xiang

и другие.

Chemical Communications, Год журнала: 2024, Номер 60(18), С. 2556 - 2559

Опубликована: Янв. 1, 2024

3-(2-Isocyanophenyl)quinazolin-4(3 H )-ones were designed and synthesized as new building units for the construction of novel quinoxalino[2,1- b ]quinazolinones under mild, photocatalytic metal-free conditions.

Язык: Английский

Процитировано

5

(NH4)2S2O8 promoted tandem radical cyclization of quinazolin-4(3H)-ones with oxamic acids for the construction of fused quinazolinones under metal-free conditions DOI
Shenyuan Gao, Menglu Cai, Gang Xu

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер 22(11), С. 2241 - 2251

Опубликована: Янв. 1, 2024

A novel cascade radical addition/cyclization reaction of non-activated olefins and oxamic acids has been proposed.

Язык: Английский

Процитировано

5

Visible Light-Induced Radical Cascade Difluoromethylation/Cyclization of Unactivated Alkenes: Access to CF2H-Substituted Polycyclic Imidazoles DOI Creative Commons
S.J. Lin, Yuanyuan Deng,

Hanxun Zhong

и другие.

ACS Omega, Год журнала: 2024, Номер 9(26), С. 28129 - 28143

Опубликована: Июнь 19, 2024

An efficient and mild protocol for the visible light-induced radical cascade difluoromethylation/cyclization of imidazoles with unactivated alkenes using easily accessible bench-stable difluoromethyltriphenylphosphonium bromide as precursor -CF

Язык: Английский

Процитировано

5

Introduction of Difluoromethyl through Radical Pathways DOI
Xin Li, Qiuling Song

European Journal of Organic Chemistry, Год журнала: 2024, Номер 27(31)

Опубликована: Июнь 5, 2024

Abstract During the past decade, radical difluoromethylation has emerged as a powerful and versatile tool for incorporation of difluoromethyl into various organic compounds. These reactions feature mild reaction conditions, very good functional group compatibilities, quite broad substrate scopes, thus having drawn much attention got rapid developments. A diverse range precursors have been developed series reactions. This review summarizes discusses advance in reactions, which are organized according to protocols generating radical.

Язык: Английский

Процитировано

4

Visible-Light-Promoted bis(Difluoromethylation)/Cyclization of 2-Vinyloxy Arylalkynes to Prepare Benzofuran Derivatives DOI
Huan Wang, Yao Huang,

Qiaoyan Wu

и другие.

The Journal of Organic Chemistry, Год журнала: 2022, Номер 87(19), С. 13288 - 13299

Опубликована: Сен. 27, 2022

A visible-light-promoted difluoromethylation/cyclization of 2-vinyloxy arylalkynes was developed, providing a variety bis(difluoromethyl)-substituted benzofurans in moderate to good yields. plausible mechanism involving difluoromethyl radical cascade cyclization and solvent-promoted ionic addition proposed. This protocol has the advantages having mild reaction conditions, simple operation, functional group tolerance.

Язык: Английский

Процитировано

15