Angewandte Chemie,
Год журнала:
2022,
Номер
134(48)
Опубликована: Окт. 7, 2022
Abstract
The
carbon
dioxide
(CO
2
)
capture
and
utilization
has
attracted
a
great
attention
in
organic
synthesis.
Herein,
an
unpresented
transient
stabilization
effect
(TSE)
of
CO
is
disclosed
well
applied
to
the
electrochemical
hydrogenation
azo
compounds
hydrazine
derivatives.
Mechanistic
experiments
computational
studies
imply
that
can
radical
anion
intermediates
protect
from
potential
degradation
reactions,
finally
released
through
decarboxylation.
promotion
was
further
demonstrated
work
preliminary
study
reductive
coupling
α‐ketoesters
vicinal
diol
For
reactions
mentioned
above,
indispensable.
presented
results
shed
light
on
different
usage
could
inspire
novel
experimental
design
by
using
as
protecting
group.
Organic Chemistry Frontiers,
Год журнала:
2023,
Номер
11(2), С. 597 - 630
Опубликована: Ноя. 23, 2023
This
review
highlights
the
recent
progress
in
electrochemical
difunctionalization
of
alkenes
and
alkynes
involving
C–S/Se
bond
formation
to
access
organochalcogen
frameworks.
Advanced Synthesis & Catalysis,
Год журнала:
2024,
Номер
366(7), С. 1517 - 1522
Опубликована: Янв. 31, 2024
Abstract
A
photoredox‐catalyzed
three‐component
sulfonaminoformyloxylation
reaction
between
alkenes,
N
‐aminopyridinium
salts
and
DMF
has
been
developed,
which
avoids
the
usage
of
erosive
formic
acid
as
formyloxylation
reagent.
Besides
DMF,
alkyl
aryl
carboxylic
acids
proved
to
be
feasible
nucleophiles
afford
various
β
‐amino
esters.
The
robustness
this
method
was
further
demonstrated
by
its
applicability
in
late‐stage
modification
biological
molecules.
Control
experiments
suggested
that
a
sulfonamidyl
radical
involved
reaction.
Angewandte Chemie International Edition,
Год журнала:
2022,
Номер
61(48)
Опубликована: Окт. 7, 2022
The
carbon
dioxide
(CO2
)
capture
and
utilization
has
attracted
a
great
attention
in
organic
synthesis.
Herein,
an
unpresented
transient
stabilization
effect
(TSE)
of
CO2
is
disclosed
well
applied
to
the
electrochemical
hydrogenation
azo
compounds
hydrazine
derivatives.
Mechanistic
experiments
computational
studies
imply
that
can
radical
anion
intermediates
protect
from
potential
degradation
reactions,
finally
released
through
decarboxylation.
promotion
was
further
demonstrated
work
preliminary
study
reductive
coupling
α-ketoesters
vicinal
diol
For
reactions
mentioned
above,
indispensable.
presented
results
shed
light
on
different
usage
could
inspire
novel
experimental
design
by
using
as
protecting
group.
Green Chemistry,
Год журнала:
2023,
Номер
25(24), С. 10144 - 10181
Опубликована: Янв. 1, 2023
The
electrochemical
cascade
process
majorly
satisfies
the
essential
criteria
of
green
synthesis.
Being
an
Integrated
synthetic
strategy
it
can
produce
more
molecules
in
a
shorter
time
and
thus
provides
modern
strategic
tool
arsenal
chemists.
Abstract
An
efficient
method
for
the
synthesis
of
β
‐hydroxy‐
‐CF
3
‐thioether
has
been
developed,
utilizing
povidone‐iodine
(PVP‐I)
as
a
recyclable
catalyst
and
air
oxidant.
The
reaction
proceeded
smoothly
at
room
temperature,
yielding
desired
in
moderate
to
good
yields.
This
can
be
scaled
up
gram‐scale
without
losing
any
efficiency.
was
also
8
repetitions.
mechanism
investigated
plausible
pathway
proposed.
Advanced Synthesis & Catalysis,
Год журнала:
2022,
Номер
364(23), С. 4020 - 4025
Опубликована: Окт. 21, 2022
Abstract
A
copper‐catalyzed
multicomponent
oxysulfonylation
of
alkenes
with
cyclobutanone
oxime
esters
and
hydroxamic
acids
via
the
insertion
sulfur
dioxide
has
been
developed.
This
reaction
uses
K
2
S
O
5
as
surrogate
in
situ
generated
amidoxyl
radical
interceptor,
thus
providing
a
direct
approach
to
β‐amidoxy
sulfones
35–90%
yields.
Mechanistic
studies
revealed
that
radical‐radical
coupling
alkyl
might
be
involved
this
transformation.
magnified
image
Asian Journal of Organic Chemistry,
Год журнала:
2023,
Номер
12(12)
Опубликована: Окт. 13, 2023
Abstract
Vinyl
sulfones
are
conjugated
systems
composed
of
C=C
and
S=O,
which
considered
to
be
significant
building
blocks
in
organic
synthesis
as
coupling
agents
because
they
can
serve
Michael
acceptors
well
2π‐partners
cycloaddition
reactions.
The
attractive
bioactivity
unique
chemical
properties
the
vinyl
sulfone
skeleton
have
led
its
extensive
study
pharmaceutical
chemistry.
However,
a
systematic
comprehensive
review
routes
for
catalytic
not
been
carried
out
so
far.
In
this
paper,
applications
structures
biomolecular
syntheses
briefly
investigated,
current
methods
recent
years
using
different
catalysts
systematically
reviewed
analyzed.
Finally,
future
opportunities
challenges
application
compounds
discussed.
Chemical Communications,
Год журнала:
2022,
Номер
59(4), С. 462 - 465
Опубликована: Дек. 8, 2022
A
sulfinyl
sulfone
intermediate,
generated
in
situ
by
the
nucleophilic
addition
of
water
to
tosyl
cyanide,
dominated
subsequent
tosylation
alkenes
via
cascade
di-radical
addition/β-elimination.
