A guide to organic electroreduction using sacrificial anodes

Chemical Society Reviews, Год журнала: 2023, Номер 52(4), С. 1168 - 1188

Опубликована: Янв. 1, 2023

This review focuses on recent advances in sacrificial anode-enabled organic electroreductions.

Язык: Английский

---

Synthesis and Glycosidation of Anomeric Halides: Evolution from Early Studies to Modern Methods of the 21st Century

Chemical Reviews, Год журнала: 2022, Номер 122(13), С. 11701 - 11758

Опубликована: Июнь 8, 2022

Advances in synthetic carbohydrate chemistry have dramatically improved access to common glycans. However, many novel methods still fail adequately address challenges associated with chemical glycosylation and glycan synthesis. Since a challenge of has remained, scientists been frequently returning the traditional glycosyl donors. This review is dedicated halides that played crucial roles shaping field glycosciences continue pave way toward our understanding glycosylation.

Язык: Английский

---

Metal‐Free SF₆Activation: A New SF₅‐Based Reagent Enables Deoxyfluorination and Pentafluorosulfanylation Reactions

Angewandte Chemie International Edition, Год журнала: 2022, Номер 61(27)

Опубликована: Апрель 26, 2022

The activation of SF6 , a potent greenhouse gas, under metal-free and visible light conditions is reported. Herein, mechanistic investigations including EPR spectroscopy, NMR studies cyclic voltammetry allowed the rational design new fluorinating reagent which was synthesized from 2-electron with commercially available TDAE. This SF5 -based efficiently employed for deoxyfluorination CO2 fluorinative desulfurization CS2 allowing formation useful fluorinated amines. Moreover, first time we demonstrated that our could afford mild generation Cl-SF5 gas. finding exploited chloro-pentafluorosulfanylation alkynes alkenes.

Язык: Английский

---

Two-dimensional FePc and MnPc monolayers as promising materials for SF6 decomposition gases detection: Insights from DFT calculations

Applied Surface Science, Год журнала: 2022, Номер 608, С. 155119 - 155119

Опубликована: Окт. 5, 2022

Язык: Английский

---

Computer-Aided Design of Covalent Organic Frameworks for SF₆ Capture: The Combination of High-Throughput Screening and Machine Learning

The Journal of Physical Chemistry C, Год журнала: 2024, Номер 128(27), С. 11355 - 11366

Опубликована: Июль 2, 2024

Efficiently separating sulfur hexafluoride/nitrogen (SF6/N2) poses an urgent challenge. Four covalent organic frameworks (COFs) (Re % > 80%) with greater performance in SF6/N2 separation experiment were selected from the CURATED database by high-throughput screening this paper. XGB was among four machine learning models (SVM, RF, GBRT, and XGB) model had good fitting effects terms of both regeneration %, R2 = 0.809) ln(Sads). Relative importance analyses described that porosity infinite dilution heat are most key features for Re The binding energy, charge density difference, Bader charge, independent gradient based on Hirshfeld partition (IGMH) analysis all calculated to investigate adsorption mechanisms. GCMC simulations combined functional theory calculations revealed COF-638 exhibited excellent performance. probability distribution diagram center mass illustrates sites SF6 coadsorption.

Язык: Английский

---

Photochemical Activation of Sulfur Hexafluoride: A Tool for Fluorination and Pentafluorosulfanylation Reactions

Synthesis, Год журнала: 2022, Номер 54(22), С. 4883 - 4894

Опубликована: Июнь 16, 2022

Abstract The photoactivation of notoriously inert sulfur hexafluoride represents a challenge for photochemistry. This short review summarizes recently published efforts and the corresponding photochemical mechanisms switching between fluorination pentafluorosulfanylation reactivity organic substrates. 1 Introduction 2 Sulfur Hexafluoride (SF6) 3 Pentafluorosulfanyl (SF5) Group 4 Photoredox Catalytic Activation SF6 5 Conclusions

Язык: Английский

---

Development of SF₆ as a Formal Electrophilic Fluorinating Reagent for Photocatalyzed Oxidative Fluorination of Phosphine Oxides

Organic Letters, Год журнала: 2024, Номер 26(27), С. 5776 - 5781

Опубликована: Июнь 27, 2024

Organophosphorus–fluorine compounds are of significant utility across biology, pharmacy, and chemical synthesis. Here, we introduce a photocatalyzed oxidative-fluorination approach employing SF6 as formal electrophilic fluorinating reagent. It offers an innovative pathway to forge P(O)–F bonds. Notably, sulfur hexafluoride plays dual role both the oxidant reagent under mild conditions in this transformation. Meanwhile, method contributes environmental sustainability by consuming notorious greenhouse gas, underscoring ecological benefits our approach.

Язык: Английский

---

Activation and Catalytic Degradation of SF₆ and PhSF₅ at a Bismuth Center

Journal of the American Chemical Society, Год журнала: 2024, Номер 146(37), С. 25409 - 25415

Опубликована: Сен. 3, 2024

In this work, we report the catalytic degradation of SF

Язык: Английский

---

Metal‐Free SF₆Activation: A New SF₅‐Based Reagent Enables Deoxyfluorination and Pentafluorosulfanylation Reactions

Angewandte Chemie, Год журнала: 2022, Номер 134(27)

Опубликована: Апрель 26, 2022

Abstract The activation of SF 6 , a potent greenhouse gas, under metal‐free and visible light conditions is reported. Herein, mechanistic investigations including EPR spectroscopy, NMR studies cyclic voltammetry allowed the rational design new fluorinating reagent which was synthesized from 2‐electron with commercially available TDAE. This 5 ‐based efficiently employed for deoxyfluorination CO 2 fluorinative desulfurization CS allowing formation useful fluorinated amines. Moreover, first time we demonstrated that our could afford mild generation Cl‐SF gas. finding exploited chloro‐pentafluorosulfanylation alkynes alkenes.

Язык: Английский

---

Recent Advances in Fluorination Reactions via De‐Carboxylative and De‐Oxygenative Strategies: A Perspective

The Chemical Record, Год журнала: 2025, Номер unknown

Опубликована: Апрель 24, 2025

Abstract Organic fluorine compounds encompass a vast and diverse variety of species that possess unique biological activity due to the presence atoms. Fluorine is highly electronegative, increases lipophilicity (fat‐solubility) hydrophobicity (water‐repellent nature) molecules, often exhibit remarkable chemical thermal stability. This especially useful in drug design, as it can improve bioavailability pharmaceutical help them interact more effectively with membranes. The growing demand for fluorinated materials science, agrochemicals, medicine has made selective incorporation into organic molecules challenging but necessary component modern synthesis. Development C−F building blocks are invaluable synthesis their ability impart stability, selectivity, reactivity molecules. article provides detailed analysis two popular fluorination processes: deoxyfluorination decarboxyfluorination. Deoxyfluorination process enhancing physicochemical properties by replacing hydroxyl groups Decarboxyfluorination type reaction where transformation carboxylic acid derivatives compounds. various fluorinating reagents, mechanistic processes, synthetic uses substrate scope covered this section. When combined, these novel strategies provide effective focused approaches production bonds, offering resources obtaining review mainly focuses on construction via deoxygenative decarboxylative since 2011. We hope offers conceptual overview inspires further advancements efficient bond.

Язык: Английский

---