Tetrahedron Letters, Год журнала: 2023, Номер 116, С. 154341 - 154341
Опубликована: Янв. 2, 2023
Язык: Английский
National Science Review, Год журнала: 2023, Номер 10(6)
Опубликована: Апрель 29, 2023
Abstract Sulfur fluoride exchange (SuFEx), a new generation of click chemistry, was first presented by Sharpless, Dong and co-workers in 2014. Owing to the high stability yet efficient reactivity SVI–F bond, SuFEx has found widespread applications organic synthesis, materials science, chemical biology drug discovery. A diverse collection linkers emerged, involving gaseous SO2F2 SOF4 hubs; SOF4-derived iminosulfur oxydifluorides; O-, N- C-attached sulfonyl fluorides sulfonimidoyl fluorides; novel sulfondiimidoyl fluorides. This review summarizes progress these connectors, with an emphasis on analysing advantages disadvantages synthetic strategies connectors based concept, it is expected be beneficial researchers rapidly correctly understand this field, thus inspiring further development chemistry.
Язык: Английский
Процитировано
76
Organic & Biomolecular Chemistry, Год журнала: 2023, Номер 21(7), С. 1356 - 1372
Опубликована: Янв. 1, 2023
This review highlights key advances in the synthesis and biomolecular applications of sulfur( vi )-fluorides.
Язык: Английский
Процитировано
51
Organic Letters, Год журнала: 2023, Номер 25(4), С. 581 - 586
Опубликована: Янв. 25, 2023
A practical electrochemically driven method for fluorosulfonylation of both aryl and alkyl thianthrenium salts has been disclosed. The strategy does not need external redox reagents or metal catalysts. In combination with C-H thianthrenation aromatics, this provides a new tool the site-selective drugs.
Язык: Английский
Процитировано
46
Nature Communications, Год журнала: 2022, Номер 13(1)
Опубликована: Июнь 18, 2022
Sulfonyl fluorides are key components in the fields of chemical biology, materials science and drug discovery. In this line, highly active SO2F radical has been employed for construction sulfonyl fluorides, but utilization gaseous ClSO2F as precursor is limited due to tedious hazardous preparation. Meanwhile, synthesis from inert SO2F2 gas through a fluorosulfonyl (·SO2F) process met with inevitable difficulties high homolytic bond dissociation energy S(VI)-F bond. Here we report fluorosulfonylation strategy stereoselective alkenyl functional alkyl an air-stable crystalline benzimidazolium fluorosulfonate cationic salt reagent. This bench-stable redox-active reagent offers useful operational protocol unsaturated hydrocarbons good yield stereoselectivity, which can be further transformed into valuable moieties.
Язык: Английский
Процитировано
66
European Journal of Organic Chemistry, Год журнала: 2024, Номер 27(23)
Опубликована: Май 25, 2024
Abstract Sulfonyl fluorides have widespread applications in many fields, including organic synthesis, chemical biology, drug discovery and materials science. In particular, the past decade, a number of aliphatic sulfonyl been identified showing various biological activities. These appealing features brought about significant advancement developing synthetic methods to access fluorides. this review, we will discuss recent developments radical approaches for synthesis
Язык: Английский
Процитировано
13
Chemistry - A European Journal, Год журнала: 2024, Номер unknown
Опубликована: Июль 16, 2024
The advancement in electrochemical techniques has unlocked a new path for achieving unprecedented oxidations and reductions of aryl radical precursors controlled selective manner. This approach facilitates the construction aromatic carbon-carbon carbon-heteroatom bonds. In light green merits growing importance this technique chemistry, review aims to provide an overview recent advance generation radicals organized by precursor type, with focus on substrate scope, limitation, underlying mechanism, thereby inspiring future work generation.
Язык: Английский
Процитировано
11
Organic Letters, Год журнала: 2024, Номер 26(7), С. 1410 - 1415
Опубликована: Фев. 15, 2024
A radical hydro-fluorosulfonylation of propargyl alcohols with FSO2Cl is presented based on the photoactivation electron donor–acceptor (EDA) complex. The reaction avoids requirement for photocatalysts, bases, hydrogen donor reagents, any other additives, and harsh conditions, enabling facile synthesis various functionalized γ-hydroxy (E)-alkenylsulfonyl fluorides. These multifunctional sulfonyl fluorides can be further diversified, providing access to privileged molecules biological relevance.
Язык: Английский
Процитировано
10
Organic Chemistry Frontiers, Год журнала: 2022, Номер 9(19), С. 5299 - 5305
Опубликована: Янв. 1, 2022
Recent advances in the generation of fluorosulfonyl radicals toward sulfonyl fluorides are highlighted.
Язык: Английский
Процитировано
31
Molecules, Год журнала: 2023, Номер 28(2), С. 857 - 857
Опубликована: Янв. 15, 2023
Organic electrochemistry has attracted tremendous interest within the novel sustainable methodologies that have not only reduced undesired byproducts, but also utilized cleaner and renewable energy sources. Particularly, oxidative gained major attention. On contrary, reductive electrolysis remains an underexplored research direction. In this context, we discuss advances in transition-metal-free cathodically generated radicals for selective organic transformations since 2016. We highlight electroreductive reaction of alkyl radicals, aryl acyl silyl fluorosulfonyl trifluoromethoxyl radicals.
Язык: Английский
Процитировано
23
Organic Chemistry Frontiers, Год журнала: 2023, Номер 11(1), С. 217 - 235
Опубликована: Ноя. 14, 2023
This review summarizes the latest achievements in photochemical and electrochemical strategies for synthesis of sulfonyl fluorides focuses on novel features proposed mechanisms.
Язык: Английский
Процитировано
23