Multi-Hydroxyl POSS Supported Iridium Complexes as a Recyclable Catalyst for Selective Synthesis of N-/C-Substituted Indoles and the Total Synthesis of HIV-1 Fusion Inhibitor DOI
Jiahao Li, Li Chen, Likui Wang

и другие.

Опубликована: Янв. 1, 2023

A novel pyridyl-thiadiazole ligand has been designed, synthesized, and employed in the preparation of a heterogeneous iridium catalyst supported on multi-hydroxyl polyhedral oligomeric silsesquioxane. The as-prepared exhibits excellent catalytic activity one-pot cascade selective synthesis N-/C-substituted indole derivatives from amino alcohols via borrowing hydrogen strategy. Meanwhile, it was observed that this approach good functional group tolerance broad substrate scope. Notably, by employing system, an inhibitor against gp41-mediated HIV-1 fusion core structure could be conveniently synthesized 2-aminophenethyl alcohol benzyl 40.6% total yield for only four steps “borrowing hydrogen” Mechanistic explorations showed transformation undergoes processes, involving N/C-alkylation through strategy, oxidative cyclization. Recycling experiments disclosed easily recovered reused at least seven times with TON.

Язык: Английский

Hydrogenation of Quinones to Hydroquinones under Atmospheric Pressure Catalyzed by a Metal–Ligand Bifunctional Iridium Catalyst DOI Creative Commons
Jin Zhang, Xiangchao Xu,

Guoqiang Zhao

и другие.

Organic Letters, Год журнала: 2024, Номер 26(9), С. 1857 - 1862

Опубликована: Фев. 26, 2024

A general method for the hydrogenation of quinones to hydroquinones under atmospheric pressure has been developed. In presence [Cp*Ir(2,2′-bpyO)(H2O)] (0.5–1 mol %), a range products were obtained in high yields. Furthemore, expansion this catalytic system 1,4-benzoquinone diimines was also presented. Functional groups bpy ligand found be crucial activity iridium complexes.

Язык: Английский

Процитировано

12

Selective Conversion of Glycerol to Lactic Acid in Water via Acceptorless Dehydrogenation Catalyzed by a Water-Soluble Metal–Ligand Bifunctional Iridium Catalyst DOI
Xiangchao Xu,

Heng You,

Beixuan Dong

и другие.

Inorganic Chemistry, Год журнала: 2024, Номер 63(28), С. 12929 - 12934

Опубликована: Июль 2, 2024

An efficient method for the selective conversion of glycerol, major byproduct biodiesel manufacturing process, to lactic acid in water via acceptorless dehydrogenation has been developed. In presence a water-soluble [Cp*Ir(6,6'-(OH)

Язык: Английский

Процитировано

11

Upgrading Ethanol to n-Butanol in the Presence of Carbonate Catalyzed by a Cp*Ir Complex Bearing a Functional 2,2′-Carbonylbibenzimidazole Ligand DOI
Xiangchao Xu, Jin Zhang, Beixuan Dong

и другие.

Inorganic Chemistry, Год журнала: 2024, Номер 63(8), С. 3843 - 3849

Опубликована: Фев. 14, 2024

Upgrading ethanol to n-butanol as biofuels is an important topic for sustainable chemistry. Herein, a Cp*Ir complex bearing functional 2,2′-carbonylbibenzimidazole ligand [Cp*Ir(2,2′-COBiBzImH2)Cl][Cl] was designed and synthesized. In the presence of catalyst (0.1 mol %) Cs2CO3 (6 %), highest yield updated up 37% with 80% selectivity. NH units in are crucially catalytic activity iridium complex.

Язык: Английский

Процитировано

10

The α-trideuteromethylation of arylacetonitriles with deuterated methanol via deuterium autotransfer process catalyzed by a metal-ligand bifunctional iridium catalyst DOI
Deyun Liu, Xiangchao Xu, Peng Zhang

и другие.

Journal of Catalysis, Год журнала: 2024, Номер 430, С. 115301 - 115301

Опубликована: Янв. 18, 2024

Язык: Английский

Процитировано

8

Auto-Tandem Catalyst: From Allylic Alcohols to Secondary Alcohols via Redox Isomerization/Atmospheric Hydrogenation in Water Catalyzed by a Water-Soluble Iridium Complex Bearing a Functional Ligand DOI
Xiaozhong Chen, Beixuan Dong,

Guoqiang Zhao

и другие.

Inorganic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Фев. 13, 2025

A water-soluble iridium complex [Cp*Ir(6,6′-(OH)2-2,2′-bpy)(H2O)][OTf]2 was found to be an efficient autotandem catalyst for the synthesis of secondary alcohols via redox isomerization/atmospheric hydrogenation in water. The OH groups bpy ligand are a key factor activity catalyst. Then, mechanistic experiments and practical utilization catalytic system were presented.

Язык: Английский

Процитировано

1

Utilization of methanol for condensation interrupted chemoselective transfer hydrogenation of CC, CO, and CN bonds under low catalyst loading DOI

Anirban Sau,

Divya Mahapatra,

Sadhan Dey

и другие.

Organic Chemistry Frontiers, Год журнала: 2023, Номер 10(9), С. 2274 - 2286

Опубликована: Янв. 1, 2023

Selective transfer hydrogenation (TH) of unsaturated molecules using methanol is challenging as the in situ generated formaldehyde prone to react with active methylene ( C -methylation) or amine N core desired product.

Язык: Английский

Процитировано

12

Multi-hydroxyl POSS supported iridium complexes as a recyclable catalyst for selective synthesis of N-/C-substituted indoles and the total synthesis of HIV-1 fusion inhibitor DOI
Jiahao Li, Li Chen, Likui Wang

и другие.

Journal of Catalysis, Год журнала: 2023, Номер 429, С. 115205 - 115205

Опубликована: Ноя. 24, 2023

Язык: Английский

Процитировано

12

Poly(2,2′-Bibenzimidazole)–Supported Iridium Complex: A Recyclable Metal–Polymer Ligand Bifunctional Catalyst for the N-Methylation of Amines with Methanol DOI
Beixuan Dong, Xingliang Wu,

Lu Shen

и другие.

Inorganic Chemistry, Год журнала: 2024, Номер 63(32), С. 15072 - 15080

Опубликована: Июль 27, 2024

The design and development of new types catalysts is one the most important topics for modern chemistry. Herein, a polymer-supported iridium complex Cp*Ir@Poly(2,2'-BiBzIm) was designed synthesized by coordinative immobilization [Cp*IrCl

Язык: Английский

Процитировано

5

Direct use of methanol instead of formaldehyde or paraformaldehyde: Acceptorless dehydrogenative coupling for the synthesis of arylhydrazones catalyzed by a metal–ligand iridium bifunctional catalyst DOI
Beixuan Dong,

Yiqian He,

Xiangchao Xu

и другие.

Journal of Catalysis, Год журнала: 2024, Номер 438, С. 115685 - 115685

Опубликована: Авг. 3, 2024

Язык: Английский

Процитировано

5

Selective N-Alkylation of Aminobenzenesulfonamides with Alcohols for the Synthesis of Amino-(N-alkyl)benzenesulfonamides Catalyzed by a Metal–Ligand Bifunctional Ruthenium Catalyst DOI

Lu Shen,

Xingliang Wu,

Lili Shi

и другие.

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(12), С. 8397 - 8406

Опубликована: Июнь 3, 2024

[(

Процитировано

4