A
novel
pyridyl-thiadiazole
ligand
has
been
designed,
synthesized,
and
employed
in
the
preparation
of
a
heterogeneous
iridium
catalyst
supported
on
multi-hydroxyl
polyhedral
oligomeric
silsesquioxane.
The
as-prepared
exhibits
excellent
catalytic
activity
one-pot
cascade
selective
synthesis
N-/C-substituted
indole
derivatives
from
amino
alcohols
via
borrowing
hydrogen
strategy.
Meanwhile,
it
was
observed
that
this
approach
good
functional
group
tolerance
broad
substrate
scope.
Notably,
by
employing
system,
an
inhibitor
against
gp41-mediated
HIV-1
fusion
core
structure
could
be
conveniently
synthesized
2-aminophenethyl
alcohol
benzyl
40.6%
total
yield
for
only
four
steps
“borrowing
hydrogen”
Mechanistic
explorations
showed
transformation
undergoes
processes,
involving
N/C-alkylation
through
strategy,
oxidative
cyclization.
Recycling
experiments
disclosed
easily
recovered
reused
at
least
seven
times
with
TON.
Organic Letters,
Год журнала:
2024,
Номер
26(9), С. 1857 - 1862
Опубликована: Фев. 26, 2024
A
general
method
for
the
hydrogenation
of
quinones
to
hydroquinones
under
atmospheric
pressure
has
been
developed.
In
presence
[Cp*Ir(2,2′-bpyO)(H2O)]
(0.5–1
mol
%),
a
range
products
were
obtained
in
high
yields.
Furthemore,
expansion
this
catalytic
system
1,4-benzoquinone
diimines
was
also
presented.
Functional
groups
bpy
ligand
found
be
crucial
activity
iridium
complexes.
Inorganic Chemistry,
Год журнала:
2024,
Номер
63(28), С. 12929 - 12934
Опубликована: Июль 2, 2024
An
efficient
method
for
the
selective
conversion
of
glycerol,
major
byproduct
biodiesel
manufacturing
process,
to
lactic
acid
in
water
via
acceptorless
dehydrogenation
has
been
developed.
In
presence
a
water-soluble
[Cp*Ir(6,6'-(OH)
Inorganic Chemistry,
Год журнала:
2024,
Номер
63(8), С. 3843 - 3849
Опубликована: Фев. 14, 2024
Upgrading
ethanol
to
n-butanol
as
biofuels
is
an
important
topic
for
sustainable
chemistry.
Herein,
a
Cp*Ir
complex
bearing
functional
2,2′-carbonylbibenzimidazole
ligand
[Cp*Ir(2,2′-COBiBzImH2)Cl][Cl]
was
designed
and
synthesized.
In
the
presence
of
catalyst
(0.1
mol
%)
Cs2CO3
(6
%),
highest
yield
updated
up
37%
with
80%
selectivity.
NH
units
in
are
crucially
catalytic
activity
iridium
complex.
Inorganic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 13, 2025
A
water-soluble
iridium
complex
[Cp*Ir(6,6′-(OH)2-2,2′-bpy)(H2O)][OTf]2
was
found
to
be
an
efficient
autotandem
catalyst
for
the
synthesis
of
secondary
alcohols
via
redox
isomerization/atmospheric
hydrogenation
in
water.
The
OH
groups
bpy
ligand
are
a
key
factor
activity
catalyst.
Then,
mechanistic
experiments
and
practical
utilization
catalytic
system
were
presented.
Organic Chemistry Frontiers,
Год журнала:
2023,
Номер
10(9), С. 2274 - 2286
Опубликована: Янв. 1, 2023
Selective
transfer
hydrogenation
(TH)
of
unsaturated
molecules
using
methanol
is
challenging
as
the
in
situ
generated
formaldehyde
prone
to
react
with
active
methylene
(
C
-methylation)
or
amine
N
core
desired
product.
Inorganic Chemistry,
Год журнала:
2024,
Номер
63(32), С. 15072 - 15080
Опубликована: Июль 27, 2024
The
design
and
development
of
new
types
catalysts
is
one
the
most
important
topics
for
modern
chemistry.
Herein,
a
polymer-supported
iridium
complex
Cp*Ir@Poly(2,2'-BiBzIm)
was
designed
synthesized
by
coordinative
immobilization
[Cp*IrCl
