Pd-Catalyzed Domino Narasaka–Heck/C–H Activation/Amination Reactions: Synthesis of Bis-heterocyclic Spirocycles
Organic Letters,
Год журнала:
2023,
Номер
25(28), С. 5361 - 5365
Опубликована: Июль 12, 2023
The
palladium-catalyzed
synthesis
of
bis-heterocyclic
spirocycles
containing
both
pyrroline
and
indoline
motifs
is
reported.
Di-tert-butyldiaziridinone
used
to
functionalize
palladacycles
generated
in
situ
via
domino
Narasaka–Heck/C–H
activation
reactions.
reaction
readily
scalable,
the
spirocyclic
products
can
undergo
deprotection,
reduction,
(3
+
2)
cycloadditions,
highlighting
their
synthetic
utility.
Additionally,
kinetic
isotope
effect
experiments
support
a
turnover-limiting
C–H
functionalization
step
catalytic
cycle.
Язык: Английский
Palladium-Catalyzed Domino Cyclization and C-H Amination of 1,7-Enynes Toward N-containing Fused Quinolin-2(1H)-ones
Chemical Communications,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
A
novel
palladium-catalyzed
domino
radical
cyclization
and
C–H
amination
of
1,7-enynes
has
been
developed
for
the
rapid
establishment
N-containing
fused
quinolin-2(1
H
)-one
scaffolds.
Язык: Английский
A rapid access to fused polycyclic indolo[2,1-a]isoquinolins via Pd-catalyzed sequential Heck /C-H activation/amination reaction with diaziridinone
Chinese Chemical Letters,
Год журнала:
2025,
Номер
unknown, С. 111376 - 111376
Опубликована: Май 1, 2025
Язык: Английский
Pd-catalyzed vinyl C–H amination with diaziridinone
Organic Chemistry Frontiers,
Год журнала:
2023,
Номер
11(2), С. 484 - 488
Опубликована: Ноя. 23, 2023
3-Amino-
N
-(quinolin-8-yl)acrylamides
are
obtained
with
up
to
78%
yield
via
Pd-catalyzed
vinyl
C–H
amination
di-
tert
-butyldiaziridinone
as
a
nitrogen
source.
Язык: Английский
Photocatalysed C–H amidation of indoles enabled by tert-butyl alkyl((perfluoropyridin-4-yl)oxy)carbamate
Chemical Communications,
Год журнала:
2023,
Номер
59(76), С. 11401 - 11404
Опубликована: Янв. 1, 2023
A
new
photoinduced
amidation
protocol
was
developed
by
utilizing
the
readily
available
tert
-butyl
alkyl((perfluoropyridin-4-yl)oxy)carbamate
as
an
effective
amidyl
radical
precursor
under
mild
conditions.
Язык: Английский
Heterogeneous Catalytic C-H Activation
Elsevier eBooks,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
Язык: Английский
Chiroptical sensing for remote chiral amines via a C-H activation reaction
Chinese Chemical Letters,
Год журнала:
2024,
Номер
unknown, С. 110310 - 110310
Опубликована: Авг. 1, 2024
Язык: Английский
I2-Mediated [3 + 3] Annulation for the Construction of Indole-Pyrimidine-Pyrazole-Fused Tetracyclic Heteroarenes
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(20), С. 15164 - 15169
Опубликована: Окт. 7, 2024
An
I2-mediated
annulation
of
3-aminopyrazoles
with
indole-3-carboxaldehydes
has
been
demonstrated
for
the
first
time.
This
tandem
strategy
allows
facile
construction
indole-pyrimidine-pyrazole-fused
tetracyclic
heteroarenes
that
are
otherwise
inaccessible
by
existing
methods.
These
fused
heterocycles
exhibited
enhanced
antifungal
activities
against
Valsa
mali
and
Botryosphaeria
dothidea
compared
commercial
Xemium
fungicide.
Язык: Английский