Cu-Catalyzed biheterocyclization along with sulfonyl remote migration: Access to Marinoquinoline alkaloids and 4-sulfonyl pyrrolo[2,3-c]quinolines
Chinese Chemical Letters,
Год журнала:
2025,
Номер
unknown, С. 110915 - 110915
Опубликована: Фев. 1, 2025
Язык: Английский
De Novo Synthesis of 2,2′-Bipyridines and Related Bis-azines via Cascade Coupling and Double Pyridannulation of Isocyanides
Yu Liu,
Qiujian Tan,
Lan Bao
и другие.
Organic Letters,
Год журнала:
2024,
Номер
26(23), С. 5043 - 5048
Опубликована: Июнь 6, 2024
Herein,
we
present
a
new
and
general
protocol
for
the
assembly
of
2,2′-bipyridyls
from
nonpyridine
substrates
without
using
any
metal
catalysts
or
organometallic
reagents.
The
process
starts
coupling
two
1,3-dienyl
isocyanides
followed
by
6π-electrocyclization/aromatization
cascade
featuring
simultaneous
formation
pyridine
rings
in
single
operation.
Notably,
this
strategy
is
also
applicable
to
construction
nonsymmetrical
2-(2-pyridyl)-quinolines/-quinoxalines.
Furthermore,
aggregation-induced
emission
(AIE)
characteristics
endow
our
approach
with
great
potential
biorelevant
fields.
Язык: Английский
Access to 2-thio/selenoquinolines via domino reaction of isocyanides with sulfur and selenium in water
Chemical Communications,
Год журнала:
2023,
Номер
59(98), С. 14595 - 14598
Опубликована: Янв. 1, 2023
A
one-pot
domino
reaction
of
o
-alkenylaryl
isocyanides
with
elemental
sulfur
and
selenium
as
well
FCH
2
I
in
water
was
developed
for
the
efficient
divergent
synthesis
2-thio-/seleno-/fluoromethylthio-/fluoromethylseleno-quinoline
derivatives.
Язык: Английский
Palladium‐Catalyzed Three‐Component Process to [1,2,3]Triazolo [1,5‐c]quinazolines
ChemistrySelect,
Год журнала:
2024,
Номер
9(25)
Опубликована: Июль 1, 2024
Abstract
An
efficient
palladium‐catalyzed
three‐component
reaction
for
the
synthesis
of
tricyclic
fused
1,2,3‐triazole
derivatives
from
amino‐NH‐1,2,3‐triazoles,
isocyanide
and
iodoarenes
has
been
developed,
involving
three
new
bonds
formation
by
one
manipulation
in
moderate
to
good
yields
with
excellent
functional
group
tolerance.
Moreover,
it
is
also
suitable
other
N
‐heterocyclic
substrates
including
pyrazole,
imidazole,
indole,
tetrazole
its
derivatives.
Язык: Английский
Synthesis of 2,3-Diperfluoroalkylated Quinoxalines via Selenium-Catalyzed Reductive C–C Coupling of Vicinal Perfluoroalkyl Formimidoyl Chlorides
Organic Letters,
Год журнала:
2024,
Номер
26(41), С. 8866 - 8871
Опубликована: Окт. 9, 2024
A
direct
and
efficient
approach
to
access
structurally
interesting
2,3-diperfluoroalkylated
quinoxalines
via
selenium-catalyzed
reductive
C-C
construction
of
vicinal
bis(perfluoroalkyl
formimidoyl
chloride)s
has
been
disclosed.
This
protocol
features
the
use
easily
accessible
starting
materials,
scalability,
a
diverse
functional
group
tolerance.
Mechanism
studies
suggested
that
this
reaction
may
involve
an
selenium-containing
seven-membered-ring
intermediate
proceed
through
electrocyclization/selenium
elimination
pathway,
which
is
significantly
different
from
traditional
transition-metal-catalyzed
coupling
strategies
alkyl
halides.
Язык: Английский