Modular synthesis of congested β2,2-amino acids via the merger of photocatalysis and oxidative functionalisations
Chemical Communications,
Год журнала:
2024,
Номер
60(11), С. 1456 - 1459
Опубликована: Янв. 1, 2024
A
two-step
protocol
for
the
modular
synthesis
of
β
2
-
and
α-quaternary
2,2
-amino
acid
derivatives
is
reported.
Язык: Английский
Base-Promoted Annulation of o-(Cyanomethyl)aryl Thioester with Thiophenols to Access 3-Thiolated Isoquinolones
Yuanyuan Fu,
Hui Liang,
F. Li
и другие.
Organic Letters,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 5, 2025
An
efficient
annulation
approach
to
forming
3-thiolated
isoquinolones
from
readily
accessible
o-(cyanomethyl)aryl
thioesters
and
thiophenols
has
been
established.
This
metal-free
is
achieved
by
taking
advantage
of
solvent-free
reactions
with
no
precaution
exclude
water
or
air,
enabling
broad
substrate
scope
good
functionality
tolerance.
Furthermore,
the
protocol
scalable
offers
facile
access
valuable
without
chromatography.
Язык: Английский
Photoredox-Enabled Deconstructive [5 + 1] Annulation Approach to Isoquinolones from Indanones in Water
Yuanyuan Fu,
Hui Liang,
Yanju Lu
и другие.
Organic Letters,
Год журнала:
2024,
Номер
26(15), С. 3043 - 3047
Опубликована: Апрель 5, 2024
We
disclose
a
deconstructive
[5
+
1]
annulation
protocol
for
the
synthesis
of
isoquinolones
through
nitrogen
insertion
into
abundant
indanones.
This
method
exploits
photoredox-catalyzed
ring-opening
oxime
esters.
The
reaction
proceeds
smoothly
with
water
as
medium
and
tolerates
range
functional
groups
on
diverse
thiophenols,
amines,
or
Moreover,
representative
exhibit
promising
antifungal
activities.
Язык: Английский