Progress in heterocyclic chemistry, Год журнала: 2024, Номер unknown, С. 421 - 484
Опубликована: Янв. 1, 2024
Язык: Английский
Progress in heterocyclic chemistry, Год журнала: 2024, Номер unknown, С. 421 - 484
Опубликована: Янв. 1, 2024
Язык: Английский
Organic Letters, Год журнала: 2025, Номер unknown
Опубликована: Фев. 27, 2025
By means of simple Rh catalysis, the direct activation ortho-C-H bond in aryl enaminones has been realized with enaminone structure as a traceless directing fragment. The products resulting from C-H alkenylation and further annulation via intramolecular addition could be accessed depending upon alkenes. annulated used for easy synthesis valuable 2-aza-fluorenones one-pot operation by employing NH4OAc.
Язык: Английский
Процитировано
2Organic Letters, Год журнала: 2024, Номер 26(24), С. 5136 - 5140
Опубликована: Июнь 7, 2024
Herein, we report a rhodium-catalyzed C–H activation/[4+2] cyclization reaction between α,β-unsaturated amides and iodonium ylides for the synthesis of novel 7,8-dihydroquinoline-2,5-diones analogues. This protocol provides series pyridones fused with saturated cycles good functional group compatibility, water air tolerance, to excellent yields under mild green conditions. Additionally, scale-up can be smoothly performed as low 0.25 mol % catalyst loading. Recycling experiments different transformation were also carried out demonstrate potential synthetic utility this protocol.
Язык: Английский
Процитировано
9Advanced Synthesis & Catalysis, Год журнала: 2024, Номер 366(8), С. 1744 - 1750
Опубликована: Фев. 22, 2024
Abstract The transmetalation triggered rhodium‐catalyzed C−H bond activation and tandem annulation of 2‐biphenylboronic acids with sulfoxonium ylides or iodonium has been developed. Various products phenanthrenes were constructed under redox‐neutral conditions in 34–86% yields. Several mechanism exploration experiments derivatization reactions conducted sequence to gain a deeper understanding the process potential this transformation. It offers an alternative approach for synthesis phenanthrene derivatives.
Язык: Английский
Процитировано
6Advances in heterocyclic chemistry, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown
Опубликована: Май 29, 2025
Iridium(III)-catalyzed regioselective cyclization of substituted oximes with iodonium ylides has been described. This methodology offered multisubstituted heterocyclic N-oxides under mild reaction conditions in a redox-neutral manner. The was also compatible vinyl oximes. Additionally, substrate diversification carried out to illustrate the synthetic application protocol. A possible mechanism involving C-H bond activation proposed as well supported by isolation key five-membered iridacycle intermediate.
Язык: Английский
Процитировано
0Topics in Catalysis, Год журнала: 2023, Номер 67(1-4), С. 246 - 262
Опубликована: Окт. 24, 2023
Язык: Английский
Процитировано
6Molecules, Год журнала: 2024, Номер 29(15), С. 3567 - 3567
Опубликована: Июль 29, 2024
Transition-metal-catalyzed directed C-H functionalization with various carbene precursors has been widely employed for constructing a wide range of complex and diverse active molecules through metal migratory insertion processes. Among precursors, iodonium ylides serve as novel emerging precursor features including easy accessibility, thermal stability high activity, which have attracted great attention from organic chemists achieved tremendous success in transformation. In this review, recent progress on the application multifunctional coupling characteristics bond activation reactions is summarized, potential discussed.
Язык: Английский
Процитировано
2Organometallics, Год журнала: 2023, Номер 42(16), С. 2228 - 2237
Опубликована: Авг. 7, 2023
An efficient iridium-catalyzed C–H activation/annulation reaction utilizing pyridotriazole as the traceless bifunctional directing group and carbene precursor to form 1H-isochromenes was described. This proceeded smoothly under an additive-free condition at room temperature, which is compatible with a wide range of functional groups in high yields.
Язык: Английский
Процитировано
4The Journal of Organic Chemistry, Год журнала: 2023, Номер 88(22), С. 15597 - 15607
Опубликована: Ноя. 2, 2023
Amide and lactam frameworks were synthesized via an efficient two-step strategy. In this protocol, pyridotriazoles first treated with isocyanates to form the corresponding amides, which found be sufficiently reactive undergo subsequent intramolecular N-H insertion in absence of any additional reagents or catalysts.
Язык: Английский
Процитировано
4Chinese Journal of Chemistry, Год журнала: 2024, Номер 42(17), С. 1986 - 1992
Опубликована: Апрель 25, 2024
Comprehensive Summary The rhodium‐catalyzed C—H bond activation and cyclization of 3‐oxopent‐4‐enenitriles with alkynes proceed efficiently. Various 2 H ‐pyrans multiple substituents are achieved in good yields through regioselective formation C—O C—C bonds. Transformations involving hydroxy‐alkynoates resulted products a furo[3,4‐ b ]pyran skeleton via further intramolecular ester exchange processes. Different from the traditional “1‐oxatrienes pathway”, this method for synthesis useful possesses certain highlights terms readily available substrates, stable easily derivatized products, gentle convenient operation process, step atom economy.
Язык: Английский
Процитировано
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