Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(23), С. 6742 - 6747
Опубликована: Янв. 1, 2024
A novel method for electrochemical C(sp 2 )–H lactonization was developed.
Язык: Английский
Organic Letters, Год журнала: 2024, Номер 26(9), С. 1936 - 1940
Опубликована: Фев. 26, 2024
A novel method for electrochemical lactonization via C(
Язык: Английский
Процитировано
7
Tetrahedron, Год журнала: 2025, Номер 176, С. 134560 - 134560
Опубликована: Фев. 24, 2025
Язык: Английский
Процитировано
0
Nature Communications, Год журнала: 2025, Номер 16(1)
Опубликована: Апрель 19, 2025
Next-generation techniques for sustainable carboxylate production generate salts as the primary outcome. To circumvent costly conversion of to acids, we demonstrate aqueous (non-)Kolbe electrolysis process an alternative strategy downstream value-added chemicals. Upon revealing irreversible oxidation-induced charge transfer inhibition on graphite anode, propose anion intercalation mitigate stability problem induced by ever-increasing overpotential. In acetate decarboxylation, observe a high Faradaic efficiency ~95% non-Kolbe products (methanol and methyl acetate) at wide current densities ranging from 0.05 1 A cm-2 long-term 0.15 0.6 130 35 h, respectively. We also extended this upgrading long-chain carboxylates such propionate, butyrate, succinate. Our work provides valuable guidance extendable overcoming passivation challenges in catalysis.
Язык: Английский
Процитировано
0
Current Research in Food Science, Год журнала: 2024, Номер 8, С. 100702 - 100702
Опубликована: Янв. 1, 2024
Phytosterol organic acid esters are important food resources and the components of biomembrane structure. Due to lack extraction synthesis techniques, more research has been focused on phytosterols, phytosterol have encountered a bottleneck, but confer substantial benefits human health. In this study, stigmasteryl vanillate (VAN), protocatechuate (PRO) sinapate (SIN) were prepared through Steglich reaction. The processes promotable products reach up 95% purity. addition, their stability was evaluated by differential scanning calorimetry thermogravimetric analysis. HPLC analysis revealed an enhancement in water solubility after esterification with phenolic acid. vitro digestion model, bioaccessibility phenolates significantly higher than that stigmasterols (STIs). Regarding anti-inflammatory properties, VAN, PRO, SIN exhibit superior effects against TNF-α induced pro-inflammatory responses compared STI. All supplementation increased ATP production, basal, maximal oxygen consumption rate mitochondrial stress test. Overall, we present method for phenolates. It will contribute development ester analysis, functions utilization food. Moreover, nutrient-stigmasterol hybrids tactic constructed is practical can become targeted delivery strategy enhanced effects.
Язык: Английский
Процитировано
3
Chemical Science, Год журнала: 2024, Номер 15(24), С. 9353 - 9360
Опубликована: Янв. 1, 2024
An expedient synthesis of electron-deficient styrenes is accomplished through decarboxylation and oxidation via halogen ion transfer. The resulting umpoled intermediates undergo a rebound elimination to furnish olefins.
Язык: Английский
Процитировано
3
ACS Organic & Inorganic Au, Год журнала: 2024, Номер 4(6), С. 579 - 603
Опубликована: Окт. 2, 2024
Organic electrosynthesis has gained much attention over the last few decades as a promising alternative to traditional synthesis methods. Electrochemical approaches offer numerous advantages organic procedures. One of most interesting aspects electroorganic is ability tune many parameters affect outcome reaction interest. such parameter composition working electrode. By changing electrode material, one can influence selectivity, product distribution, and rate reactions. In this Review, we describe several materials modifications with applications in electrosynthetic transformations. Included discussion are electrodes nanoparticles, composite materials, polymers, frameworks, surface-bound mediators. We first discuss important physicochemical electrochemical properties each material. Then, briefly summarize relevant examples class electrodes, goal providing readers catalog for wide variety syntheses.
Язык: Английский
Процитировано
2
Chemistry - A European Journal, Год журнала: 2024, Номер unknown
Опубликована: Авг. 19, 2024
Decarboxylative cross-coupling reactions are powerful tools for carbon-heteroatom bonds formation, but typically require pre-activated carboxylic acids as substrates or heteroelectrophiles functional groups. Herein, we present an electrochemical decarboxylative of with structurally diverse fluorine, alcohol, H
Язык: Английский
Процитировано
1
Chemistry - A European Journal, Год журнала: 2024, Номер 30(66)
Опубликована: Окт. 16, 2024
Abstract Carboxylic acids are attractive synthetic feedstocks with stable, non‐toxic, and inexpensive properties that can be easily obtained from natural sources or through synthesis. have long been considered environmentally friendly coupling agents in various organic transformations. In recent years, electrochemically mediated decarboxylation reactions of decarboxylic their derivatives (NHPI) emerged as effective new methods for constructing carbon‐carbon carbon‐heterocarbon chemical bonds. Compared transition metal photochemistry‐mediated catalytic reactions, which do not require the addition oxidants strong bases, electrochemically‐mediated decarboxylative transformations a sustainable strategy. addition, functional groups tolerate electrochemical conversion strategy well. Here, we summarize to better elucidate advantages reactions.
Язык: Английский
Процитировано
1
Organic Letters, Год журнала: 2024, Номер 26(44), С. 9547 - 9552
Опубликована: Окт. 25, 2024
α,β-Dehydrogenation of flavanones represents an ideal strategy to synthesize various flavones but remains challenging because the requirements for rigorous conditions. Herein, a straightforward and efficient route synthesis via electrocatalysis is disclosed. This electro-oxidative approach shows broad substrate scope, including azaflavanones thioflavanones, which could be performed in undivided cell without removal air or water absence metal catalysts, ligands, external oxidants. Moreover, combination cyclic voltammetry, square wave voltammetry experiments, density functional theory (DFT) calculations revealed plausible mechanism.
Язык: Английский
Процитировано
1
Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(23), С. 6742 - 6747
Опубликована: Янв. 1, 2024
A novel method for electrochemical C(sp 2 )–H lactonization was developed.
Язык: Английский
Процитировано
0