Organoselenium Catalyzed Electrochemical Cascade Cyclization: An Access to Naphthofuran‐2‐carboxaldehyde
Advanced Synthesis & Catalysis,
Год журнала:
2024,
Номер
366(11), С. 2544 - 2550
Опубликована: Апрель 5, 2024
Abstract
We
have
developed
an
approach
for
the
construction
of
naphthofuran‐2‐carboxaldehyde
derivatives
utilizing
synergy
electrochemical
oxidation
and
organo‐selenium
catalysis
at
room
temperature.
The
compatibility
various
functional
groups
scalability
this
protocol
demonstrate
practicality
strategy.
synthetic
utility
strategy
is
furthermore
demonstrated
by
synthesizing
diversified
molecules
through
downstream
transformations.
Язык: Английский
Progress in Electrochemically Empowered C−O Bond Formation: Unveiling the Pathway of Efficient Green Synthesis
Debosmit Ghosh,
Aroop Kumar Samal,
Anita Parida
и другие.
Chemistry - An Asian Journal,
Год журнала:
2024,
Номер
19(11)
Опубликована: Апрель 8, 2024
Abstract
(C−X)
bonds
(X=C,
N,
O)
are
the
main
backbone
for
making
different
skeleton
in
organic
synthetic
transformations.
Among
all
sustainable
techniques,
electro‐organic
synthesis
C−X
bond
formation
is
advanced
tool
as
it
offers
a
greener
and
more
cost‐effective
approach
to
chemical
reactions
by
utilizing
electrons
reagents.
In
this
review,
we
want
explore
recent
advancements
electrochemical
C−O
formation.
The
electrochemically
driven
represents
an
emerging
exciting
area
of
research.
context,
techniques
numerous
advantages,
including
higher
yields,
cost‐efficient
production,
simplified
work‐up
procedures.
This
method
enables
continuous
consistent
molecules,
significantly
enhancing
overall
reaction
yields.
Furthermore,
both
intramolecular
intermolecular
forming
provided
valuable
products
O‐containing
acyclic/cyclic
analogue.
Hence,
carbonyl
(C=O),
ether
‐O‐),
ester
(‐COOR)
functionalization
cyclic/acyclic
analogues
have
been
prepared
continuously
via
innovative
pathway.
discuss
one‐decade
pathways
various
contains
functional
group
chronological
manner.
review
focused
on
aspects
mechanistic
path
has
also
mentioned
critical
finding
regarding
pathways.
Язык: Английский
Regioselective Access to Substituted Benzothiophenes/furans through Electrochemical Selenium-Promoted Skeletal Rearrangement
Organic Letters,
Год журнала:
2025,
Номер
27(4), С. 961 - 966
Опубликована: Янв. 21, 2025
An
electrochemical
strategy
for
the
regioselective
construction
of
seleno-benzothiophenes/furans
is
reported
through
selenocyclization,
followed
by
Wagner-Meerwein
rearrangement.
This
electro-oxidative
tandem
process
operates
under
metal-free
and
external
chemical
oxidant-free
conditions.
Advantageously,
unprotected
homopropargyl
alcohols
were
found
to
be
compatible
reaction
conditions,
releasing
water
dihydrogen
as
biproduct.
methodology
reveals
good
functional
group
tolerance,
allowing
a
broad
spectrum
substrate
scopes
up
87%
isolated
yield.
Язык: Английский
Batch and Continuous-Flow Electrochemical Geminal Difluorination of Indeno[1,2-c]furans
Guo-Cai Yuan,
Fang‐Ling Gao,
Kang-Wei Liu
и другие.
Organic Letters,
Год журнала:
2024,
Номер
26(28), С. 6059 - 6064
Опубликована: Июль 5, 2024
An
electrochemical
gem-difluorination
of
indeno[1,2-c]furans
using
commercially
available
and
easy-to-use
triethylamine
trihydrofluoride
as
both
the
electrolyte
fluorinating
agent
was
developed.
Remarkably,
different
reaction
pathways
indeno[1,2-c]furans,
i.e.,
paired
electrolysis
net
oxidation,
are
operative
in
a
batch
reactor
continuous-flow
microreactor
to
afford
corresponding
gem-difluorinated
indanones
indenones,
respectively.
Язык: Английский
Electrochemically Driven Metal-Free Synthesis of Benzylic Thioethers via C-S Cross-Coupling
Organic Chemistry Frontiers,
Год журнала:
2024,
Номер
11(23), С. 6790 - 6796
Опубликована: Янв. 1, 2024
An
electrochemically
driven
C–S
radical–radical
cross-coupling
reaction
between
benzyl
halides
and
disulfides
for
the
synthesis
of
benzylic
thioethers
has
been
developed
under
environmentally
friendly
mild
conditions.
Язык: Английский
Synthesis of Selenooxazoles through Electrochemical Oxidative Selenocyclization of N‐Propargylamides
Advanced Synthesis & Catalysis,
Год журнала:
2023,
Номер
366(3), С. 408 - 413
Опубликована: Дек. 15, 2023
Abstract
An
electrocatalytic
approach
for
the
bromide‐mediated
selenocyclization
of
N
‐propargylamides
with
diselenides
is
described,
providing
a
synthetic
route
synthesis
various
seleno‐oxazoles
in
41–73%
yields.
The
success
gram‐scale
experiments
demonstrate
potential
value
this
protocol
chemistry.
Mechanistic
investigations
suggest
that
proceed
through
two
possible
pathways,
including
selenium
cation
and
radical
processes.
Язык: Английский