Chinese Journal of Organic Chemistry, Год журнала: 2024, Номер 44(7), С. 2147 - 2147
Опубликована: Янв. 1, 2024
Язык: Английский
Chinese Journal of Organic Chemistry, Год журнала: 2024, Номер 44(7), С. 2147 - 2147
Опубликована: Янв. 1, 2024
Язык: Английский
Organic Letters, Год журнала: 2025, Номер unknown
Опубликована: Март 19, 2025
Cascade annulation reactions can assemble structurally intricate polycyclic molecules from simple starting materials with enhanced efficiency and minimized production of waste. Presented herein is a concise effective synthesis benzoisochromene derivatives based on C-H activation-initiated cascade formal [4+2]/[2+4] aryl enaminone vinyl-1,3-dioxolan-2-one. In constructing the six-membered carbocycle, acted as C4 synthon while vinyl-1,3-dioxolan-2-one C2 synthon. O-heterocycle, other hand, former latter C3O1 To our knowledge, this first simultaneous construction both carbocycle an O-heterocycle via concurrent C-H/C-N/C-O bond cleavage C-C/C-C/C-O formation. general, novel protocol features use readily obtainable substrates broad scope, excellent atom- step-economy, intriguing reaction pathway, valuable products.
Язык: Английский
Процитировано
3Organic & Biomolecular Chemistry, Год журнала: 2024, Номер 22(29), С. 5897 - 5901
Опубликована: Янв. 1, 2024
Sulfonyl groups are motifs that widely found in biologically active compounds and drug molecules, many isolated natural products as well pharmaceuticals contain sulfonyl groups. Herein, we present the synthesis of sulfonyl-substituted isoindolones by a electrochemical oxidative radical cascade cycloaddition reaction olefinic amides with sodium sulfite under oxidant- catalyst-free conditions. Various sulfinates were compatible gave desired yields up to 99%.
Язык: Английский
Процитировано
3Chinese Journal of Organic Chemistry, Год журнала: 2024, Номер 44(7), С. 2147 - 2147
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
0