Chinese Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 44(7), P. 2147 - 2147
Published: Jan. 1, 2024
Language: Английский
Chinese Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 44(7), P. 2147 - 2147
Published: Jan. 1, 2024
Language: Английский
Organic Letters, Journal Year: 2025, Volume and Issue: unknown
Published: March 19, 2025
Cascade annulation reactions can assemble structurally intricate polycyclic molecules from simple starting materials with enhanced efficiency and minimized production of waste. Presented herein is a concise effective synthesis benzoisochromene derivatives based on C-H activation-initiated cascade formal [4+2]/[2+4] aryl enaminone vinyl-1,3-dioxolan-2-one. In constructing the six-membered carbocycle, acted as C4 synthon while vinyl-1,3-dioxolan-2-one C2 synthon. O-heterocycle, other hand, former latter C3O1 To our knowledge, this first simultaneous construction both carbocycle an O-heterocycle via concurrent C-H/C-N/C-O bond cleavage C-C/C-C/C-O formation. general, novel protocol features use readily obtainable substrates broad scope, excellent atom- step-economy, intriguing reaction pathway, valuable products.
Language: Английский
Citations
3Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(29), P. 5897 - 5901
Published: Jan. 1, 2024
Sulfonyl groups are motifs that widely found in biologically active compounds and drug molecules, many isolated natural products as well pharmaceuticals contain sulfonyl groups. Herein, we present the synthesis of sulfonyl-substituted isoindolones by a electrochemical oxidative radical cascade cycloaddition reaction olefinic amides with sodium sulfite under oxidant- catalyst-free conditions. Various sulfinates were compatible gave desired yields up to 99%.
Language: Английский
Citations
3Chinese Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 44(7), P. 2147 - 2147
Published: Jan. 1, 2024
Language: Английский
Citations
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