Regioselective [3 + 2] Annulation of β,γ-Alkynyl-α-ketimino Esters with 1,3-Dicarbonyls: The Synthesis of Highly Functionalized Dihydrofurans

The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 30, 2025

A regioselective [3 + 2] annulation of β,γ-alkynyl-α-ketimino esters with 1,3-dicarbonyls is disclosed. series Z-selective dihydrofurans bearing an exocyclic double bond and a quaternary carbon center are accessed without the usage base. Control deuterium-labeling experiments have been investigated to probe into reaction mechanism. The catalyst base-free nucleophilic addition highlights transformation.

Язык: Английский

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The application and development of cyanating reagents in asymmetric cyanation reactions

Tetrahedron Letters, Год журнала: 2025, Номер unknown, С. 155549 - 155549

Опубликована: Март 1, 2025

Язык: Английский

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Bridging linker installation strategy in the engineering of copper(ii) complexes: activation of nitriles, efficient catalysts for the cyanosilylation of aldehydes

CrystEngComm, Год журнала: 2024, Номер 26(47), С. 6692 - 6700

Опубликована: Янв. 1, 2024

No trend was detected between the linker length and catalytic activity of bridged copper( ii )-arylhydrazone complexes in cyanosilylation benzaldehyde with trimethylsilyl cyanide.

Язык: Английский

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Chiral Ru-Li Combined Catalysts for Asymmetric Cyanation of α-Ketimino Ester Derivatives

Synfacts, Год журнала: 2024, Номер 20(05), С. 0547 - 0547

Опубликована: Апрель 15, 2024

Key words asymmetric cyanation - chiral catalysis enantioselectivity quaternary amino acids click chemistry

Язык: Английский

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