Organic Letters,
Год журнала:
2024,
Номер
26(41), С. 8934 - 8938
Опубликована: Окт. 9, 2024
A
copper-catalyzed
decarboxylative
aminomethylation
of
indole-3-carboxylic
acids
with
1,2-oxazetidines
has
been
developed,
enabling
the
rapid
synthesis
structurally
diverse
3-aminomethylindoles
in
good
to
excellent
yields.
Remarkably,
an
unprecedented
aminomethylation/cyclization
cascade
was
further
achieved
by
a
combination
copper
and
iron
salts
construct
complex
γ-carbolines
high
efficiency.
It
is
worth
noting
that
one
obtained
products
proved
be
dual-emissive
luminogen,
exhibiting
both
aggregation-caused
quenching
aggregation-induced
emission.
Chemical Communications,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
This
mini-review
highlights
the
scientific
breakthroughs
in
photochemical
upcycling
polymers
through
oxidative
degradation
and
post-polymerization
modification
via
visible
light-driven
C–H
bond
activation.
Stable
and
easy-to-handle
sodium
salts
of
sulfonyl
oximes
were
first
identified
to
proceed
via
visible-light-driven
phophine-mediated
successive
deoxygenation
realize
the
Abstract
Rapid
access
to
unsymmetrical
diaryl
sulfides
through
a
bifunctional
single‐sulfur
source
is
very
attractive
strategy.
Here
we
report
the
utilization
of
bis(phenylsulfonyl)sulfide
as
bielectrophilic
sulfide
platform
molecule
for
chemoselective
and
sequential
installation
two
different
aryl
nucleophiles
by
twice
copper‐catalyzed
Chan–Lam‐type
cross
couplings
diverse
sulfides.
This
strategy
demonstrates
good
tolerance
wide
range
boronic
acids
under
metal
catalysts,
functional
group
compatibility,
well
extension
modification
complex
bioactive
molecules.
Organic Letters,
Год журнала:
2024,
Номер
26(43), С. 9383 - 9388
Опубликована: Окт. 22, 2024
Herein,
a
direct
transformation
of
aliphatic
C–H
bonds
to
oxime
ethers
has
been
developed
via
light-promoted
hydrogen
atom
transfer
(HAT)
in
the
absence
photocatalyst.
Singlet
oxygen
and
chlorine
radical
are
complementary
C(sp3)–H
bond
cleaving
agents
this
reaction,
enabling
extraction
atoms
from
diverse
range
compounds,
like
cycloalkanes,
ethers,
amines,
amides,
cyclic
sulfides.
This
method
excels
transforming
common
into
valuable
featuring
abundant
chemical
feedstocks,
good
functional
group
tolerance,
catalyst
free
conditions.
Organic Letters,
Год журнала:
2024,
Номер
26(41), С. 8934 - 8938
Опубликована: Окт. 9, 2024
A
copper-catalyzed
decarboxylative
aminomethylation
of
indole-3-carboxylic
acids
with
1,2-oxazetidines
has
been
developed,
enabling
the
rapid
synthesis
structurally
diverse
3-aminomethylindoles
in
good
to
excellent
yields.
Remarkably,
an
unprecedented
aminomethylation/cyclization
cascade
was
further
achieved
by
a
combination
copper
and
iron
salts
construct
complex
γ-carbolines
high
efficiency.
It
is
worth
noting
that
one
obtained
products
proved
be
dual-emissive
luminogen,
exhibiting
both
aggregation-caused
quenching
aggregation-induced
emission.
