Decarboxylative Aminomethylation of Indole-3-carboxylic Acids via Strain Release-Driven Ring Opening of 1,2-Oxazetidines DOI
Zi‐Kui Liu,

Yun Liu,

Xiao‐Qiang Hu

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(41), P. 8934 - 8938

Published: Oct. 9, 2024

A copper-catalyzed decarboxylative aminomethylation of indole-3-carboxylic acids with 1,2-oxazetidines has been developed, enabling the rapid synthesis structurally diverse 3-aminomethylindoles in good to excellent yields. Remarkably, an unprecedented aminomethylation/cyclization cascade was further achieved by a combination copper and iron salts construct complex γ-carbolines high efficiency. It is worth noting that one obtained products proved be dual-emissive luminogen, exhibiting both aggregation-caused quenching aggregation-induced emission.

Language: Английский

Visible-Light-Promoted Iron(II)/Lewis Base Catalysis for the Alkylation of Morita–Baylis–Hillman Acetates Using Carboxylic Acids DOI

Durga Golagani,

Kota Krishna Prakash,

Satyam Thapa

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 1, 2024

A novel photoinduced Fe(OTf)

Language: Английский

Citations

3
Photochemical upcycling of polymers via visible light-driven C−H bond activation DOI
Yi Wei, Jing Liu, Xiao‐Qiang Hu

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

This mini-review highlights the scientific breakthroughs in photochemical upcycling polymers through oxidative degradation and post-polymerization modification via visible light-driven C–H bond activation.

Language: Английский

Citations

3
Photoredox-Catalyzed Phosphine-Mediated Successive Deoxygenation of Sulfonyl Oxime Salts Enables Anti-Markovnikov Hydrothiolation of Alkenes DOI
Zhenzhen Xie, Cong Huang, Jie Gao

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 17, 2024

Stable and easy-to-handle sodium salts of sulfonyl oximes were first identified to proceed via visible-light-driven phophine-mediated successive deoxygenation realize the

Language: Английский

Citations

1
Bis(phenylsulfonyl)sulfide as a Bifunctional Single‐Sulfur Source for the Rapid Assembly of Unsymmetric Diaryl Sulfides Enabled by Copper Catalyst DOI
Jianbo Wang, Yong Zhou, Chaoqun Huang

et al.

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(44)

Published: Nov. 1, 2024

Abstract Rapid access to unsymmetrical diaryl sulfides through a bifunctional single‐sulfur source is very attractive strategy. Here we report the utilization of bis(phenylsulfonyl)sulfide as bielectrophilic sulfide platform molecule for chemoselective and sequential installation two different aryl nucleophiles by twice copper‐catalyzed Chan–Lam‐type cross couplings diverse sulfides. This strategy demonstrates good tolerance wide range boronic acids under metal catalysts, functional group compatibility, well extension modification complex bioactive molecules.

Language: Английский

Citations

1
Photocatalyst-Free Transformation of C(sp3)–H Bonds to Oxime Ethers via Photoinduced Hydrogen Atom Transfer DOI

Yulian Zhao,

Xuehong Min,

Lijing Li

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(43), P. 9383 - 9388

Published: Oct. 22, 2024

Herein, a direct transformation of aliphatic C–H bonds to oxime ethers has been developed via light-promoted hydrogen atom transfer (HAT) in the absence photocatalyst. Singlet oxygen and chlorine radical are complementary C(sp3)–H bond cleaving agents this reaction, enabling extraction atoms from diverse range compounds, like cycloalkanes, ethers, amines, amides, cyclic sulfides. This method excels transforming common into valuable featuring abundant chemical feedstocks, good functional group tolerance, catalyst free conditions.

Language: Английский

Citations

0
Decarboxylative Aminomethylation of Indole-3-carboxylic Acids via Strain Release-Driven Ring Opening of 1,2-Oxazetidines DOI
Zi‐Kui Liu,

Yun Liu,

Xiao‐Qiang Hu

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(41), P. 8934 - 8938

Published: Oct. 9, 2024

A copper-catalyzed decarboxylative aminomethylation of indole-3-carboxylic acids with 1,2-oxazetidines has been developed, enabling the rapid synthesis structurally diverse 3-aminomethylindoles in good to excellent yields. Remarkably, an unprecedented aminomethylation/cyclization cascade was further achieved by a combination copper and iron salts construct complex γ-carbolines high efficiency. It is worth noting that one obtained products proved be dual-emissive luminogen, exhibiting both aggregation-caused quenching aggregation-induced emission.

Language: Английский

Citations

0