Visible-Light-Mediated Perfluoroalkylation/Thioetherification of [1.1.1]Propellane under Photocatalyst-Free Conditions DOI
Jiabin Shen,

Liangfeng Yang,

Ge Kai

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Май 29, 2025

Perfluoroalkyl-functionalized bicyclo[1.1.1]pentane (BCP) derivatives have garnered significant attention in pharmaceuticals due to their special physicochemical property; however, establishing convenient synthetic protocols for these fluorinated molecular frameworks continues present substantial methodological challenges. Herein, we report a photocatalyst and additive-free perfluoroalkylation/thioetherification of [1.1.1] propellane with disulfide ether perfluoroalkyl iodines. Such photochemistry methodology utilizing an electron donor-acceptor (EDA) complex offers green novel way obtain various BCP containing thioether groups good functional group tolerance.

Язык: Английский

Photoelectrochemical upcycling of PVC plastic waste for the synthesis of chlorinated quinolinone derivatives DOI
Kai Zheng, Jingwen He, Zhang Li-xi

и другие.

Organic Chemistry Frontiers, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Herein, an environmentally friendly methodology has been established for the photoelectrochemical chlorination of C(sp 2 )–H bonds in quinolinone derivatives using PVC plastic waste as chlorine source.

Язык: Английский

Процитировано

3

Heterogeneous g-C3N4/NaI Dual Catalytic Difunctionalization of Alkenes with Heteroarenes and Methyl Carbazate under Visible Light DOI
Kai Zheng, Chao Chen,

Yacong Wang

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Апрель 26, 2025

Herein, a photoinduced heterogeneous catalytic system merging g-C3N4 and NaI has been established for the difunctionalization of alkenes in conjunction with heteroarenes methyl carbazate. This approach is notable its broad substrate tolerance, encompassing wide range leading to formation corresponding esters moderate good yields. Additionally, scalability synthetic process versatility product transformations have illustrated, highlighting potential practical application organic synthesis.

Язык: Английский

Процитировано

2

Highly Efficient and Sustainable HT@NC/Pd Catalysts for Suzuki Coupling and Their Application in Elacestrant Synthesis DOI Open Access
Jiajun He,

Minmin Liu,

Chao Chen

и другие.

Catalysts, Год журнала: 2025, Номер 15(4), С. 389 - 389

Опубликована: Апрель 17, 2025

Mg-Al hydrotalcite (HT), comprising Mg2+ and Al3+ as layered hydroxide cations, was synthesized via a hydrothermal process at 200 °C. The HT evaluated carrier, subsequently, palladium immobilized on the surface of (HT/NC), resulting in development an innovative biomass-based catalyst. catalyst underwent analysis by X-ray diffraction (XRD), scanning electron microscopy (SEM), photoelectron spectroscopy (XPS). It exhibited remarkable catalytic efficiency superior activity Suzuki–Miyaura coupling reaction water. recyclable without decline could be utilized more than 10 times, with exceptional yield. Furthermore, commercially accessible anticancer drug Elacestrant can readily produced using this protocol.

Язык: Английский

Процитировано

0

Photo-induced aerobic cross-coupling of quinoxalin-2(1H)-ones with electron-rich thiophenes DOI
Wei Huang, Tong Wang, Shuying Chen

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Herein, an efficient aerobic cross-coupling of quinoxazolines with electron-rich thiophenes was presented. It's easy and effective access to 3-thiophenyl quinoxalinones without external photo-catalyst or transition-metal catalyst.

Язык: Английский

Процитировано

0

Visible-Light-Mediated Perfluoroalkylation/Thioetherification of [1.1.1]Propellane under Photocatalyst-Free Conditions DOI
Jiabin Shen,

Liangfeng Yang,

Ge Kai

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Май 29, 2025

Perfluoroalkyl-functionalized bicyclo[1.1.1]pentane (BCP) derivatives have garnered significant attention in pharmaceuticals due to their special physicochemical property; however, establishing convenient synthetic protocols for these fluorinated molecular frameworks continues present substantial methodological challenges. Herein, we report a photocatalyst and additive-free perfluoroalkylation/thioetherification of [1.1.1] propellane with disulfide ether perfluoroalkyl iodines. Such photochemistry methodology utilizing an electron donor-acceptor (EDA) complex offers green novel way obtain various BCP containing thioether groups good functional group tolerance.

Язык: Английский

Процитировано

0