European Journal of Inorganic Chemistry,
Год журнала:
2023,
Номер
26(14)
Опубликована: Март 7, 2023
Abstract
A
series
of
new
alkynylamidinate
complexes
selected
first
and
second
row
transition
metals
has
been
synthesized
fully
characterized.
Treatment
MCl
2
precursors
(M=Mn,
Fe,
Co)
with
equiv.
the
lithium
alkynylamidinates
Li[
c
‐C
3
H
5
−C≡C−C(NR′)
]
⋅
THF
(R′=
i
Pr
(2),
Cy
(cyclohexyl)
(
))
afforded
a
binuclear
type
M
[
−C≡C−C(NR)
‐κ
N
:κ
N′
,
:
M=Mn,
R=Cy;
4
M=Fe,
R=
Pr;
b
M=Co,
Pr)
no
significant
metal‐metal
bonding.
In
marked
contrast,
similar
reaction
CrCl
1
homoleptic
dinuclear
chromium(II)
complex
Cr
−C≡C−C(N
6
)
which
supposedly
comprises
Cr−Cr
quadruple
bond.
Complex
could
also
be
prepared
in
more
rational
way
better
yield
(61
%)
by
using
dichromium(II)
tetraacetate,
(OAc)
as
starting
material.
Related
reactions
employing
dimolybdenum(II)
Mo
or
mixed‐ligand
paddle
wheel‐type
trans
‐Mo
(OAc‐κ
O
O′
([
7
)([
8
).
All
title
compounds
were
structurally
characterized
through
single‐crystal
X‐ray
diffraction
spectroscopic
techniques
(NMR,
IR,
Raman).
Chemical Communications,
Год журнала:
2020,
Номер
56(22), С. 3249 - 3252
Опубликована: Янв. 1, 2020
Efficient
access
to
cyclic
imine-containing
indoline
derivatives
through
palladium-catalysed
dearomative
aryl/cycloimidoylation
of
indoles
using
functionalized
isocyanides
has
been
developed.
Angewandte Chemie International Edition,
Год журнала:
2022,
Номер
61(42)
Опубликована: Июль 23, 2022
Herein,
we
present
a
direct
and
efficient
synthesis
of
diverse
polysubstituted
fused
tetracyclic
heterocycles
with
good
functional
group
tolerance
from
diarylalkynes
under
different
palladium
catalytic
systems.
In
this
chemistry,
an
unprecedented
intermolecular
nucleopalladation
through
the
highly
selective
sequential
double
insertion
isocyanide
was
achieved
for
first
time.
The
practicality
method
further
demonstrated
by
construction
various
bioactive
molecules
important
structural
motifs,
potential
applications
in
materials
science
biochemistry.
addition,
density
theory
calculations
(DFT)
elucidated
interesting
"Pd
walk"
during
cyclization
process.
Organic Letters,
Год журнала:
2023,
Номер
25(9), С. 1409 - 1414
Опубликована: Март 1, 2023
A
novel
and
efficient
palladium-catalyzed
annulation
of
anilines
with
bromoalkynes
for
the
synthesis
2-phenylindoles
has
been
described.
This
approach
features
excellent
regio-
stereoselectivities
good
functional
group
tolerance.
Preliminary
mechanistic
studies
indicate
that
undergo
anti-nucleophilic
addition
to
generate
(Z)-N-(2-bromo-1-phenylvinyl)
anilines,
followed
by
sequential
C-H
functionalization
deliver
different
substituted
2-phenylindoles.
method
provides
potential
applications
construction
various
biologically
active
compounds.
Molecules,
Год журнала:
2025,
Номер
30(3), С. 708 - 708
Опубликована: Фев. 5, 2025
Polydentate
ligands
with
nitrogen
donor
atoms
have
possibly
given
rise
to
the
largest
group
of
coordination
complexes
described.
Among
these
ligands,
amidinates
represent
a
nitrogenated
version
carboxylates
and
allow
formation
most
elements
in
periodic
table,
adopting
chelate
or
bridge
modes.
The
precursors
amidines,
can
present
an
alkynyl
as
substituent
their
central
atom,
R′N=C(C≡CR)NHR′,
which
provides
additional
point
reactivity
for
molecules,
well
different
electronic
behavior
compared
conventional
amidines
alkyl
groups
on
carbon
atom
amidine
group.
These
propiolamidines
been
obtained
through
classical
stoichiometric
organic
synthesis
procedures
or,
greater
atomic
economy,
catalytic
based
Main
Group,
Transition,
Rare
Earth
metals.
This
work
reviews
methods,
obtention
new,
more
complex
heterocyclic
molecules.
Chemical Communications,
Год журнала:
2024,
Номер
60(21), С. 2950 - 2953
Опубликована: Янв. 1, 2024
A
convenient
and
straight-forward
entry
to
pyrrole[2,3-
b
]indoles
ureas
via
ligand-controlled
palladium-catalyzed
chemoselective
tandem
reaction
of
2-ethynylanilines
isocyanides
has
been
established.
Advanced Synthesis & Catalysis,
Год журнала:
2020,
Номер
362(6), С. 1281 - 1285
Опубликована: Янв. 25, 2020
Abstract
Tandem
catalysis,
the
use
of
a
single
catalyst
to
promote
two
or
more
mechanistically
distinct
cycles
in
one
pot
assemble
complex
organic
molecules,
is
an
attractive
target.
In
this
paper,
we
report
reductant‐triggered
tandem
palladium
catalysis
process
that
rapidly
assembles
3,4‐fused
tricyclic
indoles
from
three
readily
available
starting
materials.
This
involves
Pd
0
‐catalyzed
situ
coupling/cyclization/Michael
addition
reaction
install
simultaneously
functional
groups
at
C4
and
C3
positions
indoles.
followed
by
intramolecular
cyclization
which
builds
seven‐membered
C4,
C3‐bridge.
Sodium
formate
used
trigger
necessary
switching
between
catalysed
reactions.
magnified
image
Chinese Journal of Chemistry,
Год журнала:
2022,
Номер
41(2), С. 181 - 187
Опубликована: Окт. 13, 2022
Comprehensive
Summary
This
report
discloses
a
distinctive
palladium‐catalyzed
sequential
tandem
cyclization
reaction
of
two
molecular
haloalkynes
and
one
N
‐alkylanilines,
leading
to
the
efficient
assembly
various
3‐halo‐1,2,5‐triarylpyrrole
derivatives.
Two
carbon‐carbon
triple
bonds
carbon‐halogen
bond
in
are
transformed
conveniently
single
step,
which
may
involve
aminoalkynylation
haloalkyne
newly
formed
enyne
intermediate.
The
high
chemo‐
regioselectivities,
good
functional
group
tolerance
late‐stage
modification
halopyrrole
products
further
illustrate
synthetic
value
this
strategy.
