CPP Functionalized Nanoparticles DOI
Ülo Langel

Springer eBooks, Год журнала: 2023, Номер unknown, С. 469 - 541

Опубликована: Янв. 1, 2023

Язык: Английский

Multifunctional Iron–Silver (Fe–Ag) Nanocomposites for Combined Anticancer Therapies: A Pathway to Enhanced Treatment Outcomes DOI

Emmanuel Faderin,

Terungwa H. Iorkula,

Kolawole E. Adesina

и другие.

˜The œminerals, metals & materials series, Год журнала: 2025, Номер unknown, С. 25 - 39

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
A review of combined imaging and therapeutic applications based on MNMs DOI Creative Commons
Yanyan Yang,

Peihong Teng,

Shu‐Hong Yu

и другие.

Frontiers in Chemistry, Год журнала: 2025, Номер 13

Опубликована: Май 26, 2025

Magnetic nanomaterials (MNMs) are nanoscale materials with inherent magnetic properties that can respond to external fields, typically composed of metals or metal oxides. These exhibit broad application prospects in medical imaging, targeted drug delivery, and cancer therapy due their exceptional properties, biocompatibility, surface functionalization capabilities. As multifunctional imaging contrast agents, have been extensively employed resonance computed tomography, positron emission tomography enhance multimodal thereby improving image resolution diagnostic accuracy. Additionally, as carriers, they be guided by fields achieve precise enhancing therapeutic efficacy while minimizing systemic side effects. In applications, utilized hyperthermia photothermal therapy, where generate localized heat via alternating conversion effects, enabling tumor microenvironment modulation ablation. This review systematically summarizes recent advances the use MNMs for a particular focus on key technical challenges emerging opportunities synergistic functions. work aims provide valuable insight into development applications precision medicine personalized therapy.

Язык: Английский

Процитировано

0
NIR-responsive porous gold nanorod dispersed in a 3D gelatin scaffold for stimulus-responsive drug release and synergistic therapy DOI Creative Commons
Snigdharani Panda, Irfan Khan, Suditi Neekhra

и другие.

Materials Advances, Год журнала: 2024, Номер 5(17), С. 6853 - 6863

Опубликована: Янв. 1, 2024

Biodegradable porous nanomaterials have emerged as a promising avenue for tumor drug delivery owing to their capacity encapsulate large quantities of drugs and compatibility with biological systems.

Язык: Английский

Процитировано

2
Radiosensitization of breast cancer cells with AgBiS2 nanodots: Preparation and in vitro evaluations DOI

Liangjun Xue,

Younes Pilehvar,

Hamed Afshari

и другие.

Applied Organometallic Chemistry, Год журнала: 2024, Номер 38(11)

Опубликована: Июль 25, 2024

Radiotherapy (RT), which is a therapeutic treatment modality that commonly used for cancer, employs high‐energy irradiation to induce the generation of reactive oxygen species (ROS) and cause DNA damages. Nevertheless, efficacy RT predominantly constrained due inadequate damage in malignancies deleterious impacts on healthy tissues. In current study, bovine serum albumin (BSA)–coated AgBiS 2 nanodots, also known as @ BSA were developed enhanced breast cancer treatment. This was accomplished by use an extremely simple eco‐friendly method. Both scanning transmission electron microscopy (STEM) (SEM) images revealed prepared nanoradiosensitizers, BSA, spherical shape uniformly distributed. nanodots possessed excellent biocompatibility exhibit monodispersity well. Furthermore, vitro assays such MTT, colony formation assay, intracellular ROS assay significant cell inhibitory impact produced under X‐ray irradiation. Remarkably, combined administration along with increased level within cells increasing localized radiation dosage improving anti‐tumor effectiveness RT.

Язык: Английский

Процитировано

2
Therapeutic and Diagnostic Uses of Magnetic Nanoparticles in Cancer DOI
Cansu İlke Kuru, Fulden Ulucan‐Karnak, Sinan Akgöl

и другие.

Опубликована: Янв. 1, 2024

Magnetic nanoparticle (MNP)-based technologies are now often used in biological systems for therapeutic or diagnostic applications. Recent developments nanotechnology have led to the creation of MNPs, which appropriate biomedical nanoparticles a class extremely adaptable instruments cancer therapy because their innate magnetic characteristics and multifunctional design. For diagnosis, monitoring, therapy, this category provides multimodal theranostics platform. In terms (MNPs) can be increase sensitivity platforms. with high moments surface-to-volume ratios attractive targeted medication delivery treatment. chapter, recent application MNPs biosensing, drug control, will provided. The field's challenges potential opportunities using enhance properties considered.

Язык: Английский

Процитировано

1
Preparation of Hybrid Fe 3 O 4 @SiO 2 Biopolymer Core-Shell Anticancer Drug Carrier for Sustainable Release of Doxorubicin DOI Creative Commons

Samia Chalal,

Nabila Haddadine, John D. Thoburn

и другие.

Research Square (Research Square), Год журнала: 2024, Номер unknown

Опубликована: Янв. 16, 2024

Abstract Magnetic core-shell drug-carrier microcapsules were prepared and investigated using doxorubicin (Dox) as an anticancer drug model. First, superparamagnetic iron oxide nanoparticles (Fe3O4), coated with silica SiO2 a sol-gel method. Next, the Fe3O4@SiO2 functionalized (3-aminopropyl) ethoxy silane (APS), to obtain Fe3O4@SiO2-NH2. Afterward, was added form Fe3O4@SiO2-NH2-(Dox), then wrapped in polymer matrix by adding chitosan/CaCl2 aqueous solution. The presence of divalent Ca2+ cations ensured hydrogel chain reticulation Fe3O4@SiO2-NH2-(Dox) encapsulation into matrix. chitosan chosen shrink microcapsules' pores limit diffusion acidic pH. Finally, solution dextran polyvinyl pyrrolidone chloroform outermost shell structure. This magnetic microcapsule noted system (A). second (B), obtained shell. two-hybrid core-shell, carriers A, B observed scanning electron microscopy (SEM) characterized ATR-FTIR spectroscopy, their characteristics confirmed. kinetic study revealed that (A) had greater release efficiency than enhanced effect at pH 5.8 7.4 associated cancer cell environments, rather 4.9 healthy environments. Therefore, carrier selected promising candidate for targeting therapy.

Язык: Английский

Процитировано

0
HMNPs@PDA-GQDs-FA as carries of gambogic acid for inhibiting VX2 tumor cells DOI
Yubing Yang, Wenwen Liu,

Xiangnong Liu

и другие.

Materials Chemistry and Physics, Год журнала: 2024, Номер unknown, С. 129957 - 129957

Опубликована: Сен. 1, 2024

Язык: Английский

Процитировано

0
pH-responsive Magnetic Nanocarriers for Chelator-free Bimodal (MRI/SPECT-CT) Image Guided Chemo-hyperthermia Therapy in Human Breast Carcinoma DOI

Bijaideep Dutta,

Neena G. Shetake,

Sourav Patra

и другие.

Journal of Materials Chemistry B, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Development of pH-Responsive magnetic nanocarriers for bimodal (MRI/SPECT-CT) image-guided chemo-thermal therapy in human breast carcinoma.

Язык: Английский

Процитировано

0
Recent progress and current status of surface engineered magnetic nanostructures in cancer theranostics DOI

Bijaideep Dutta,

K.C. Barick, P. A. Hassan

и другие.

Advances in Colloid and Interface Science, Год журнала: 2024, Номер 334, С. 103320 - 103320

Опубликована: Окт. 30, 2024

Язык: Английский

Процитировано

0
CPP Functionalized Nanoparticles DOI
Ülo Langel

Springer eBooks, Год журнала: 2023, Номер unknown, С. 469 - 541

Опубликована: Янв. 1, 2023

Язык: Английский

Процитировано

0